@article{Tacke:152286,
  author       = {Tacke, Frank and Zimmermann, Henning Wolfgang and Berres, Marie-Luise and Trautwein, Christian and Wasmuth, Hermann E.},
  title        = {Serum chemokine receptor {CXCR}3 ligands are associated with progression, organ dysfunction and complications of chronic liver diseases},
  journaltitle = {Liver international},
  year         = {2011},
  doi          = {10.1111/j.1478-3231.2011.02504.x},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {840--849},
  publisher    = {Blackwell},
  pubmed       = {pmid:21645215},
  reportid     = {RWTH-CONV-030784},
  url          = {https://publications.rwth-aachen.de/record/152286},
  volume       = {31},
}

@article{Babbar:782496,
  author       = {Babbar, Anshu and Hitch, Thomas C. A. and Pabst, Oliver and Clavel, Thomas and Hübel, Jessica and Eswaran, Sreepradha and Wagner, Norbert and Schippers, Angela},
  title        = {The Compromised Mucosal Immune System of β7 Integrin-Deficient Mice Has Only Minor Effects on the Fecal Microbiota in Homeostasis},
  journaltitle = {Frontiers in microbiology},
  year         = {2019},
  doi          = {10.3389/fmicb.2019.02284},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B02,CRC1382-Project B06,CRC1382-Project Q04,CRC1382-Project B02,CRC1382-Project B02},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {2284},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:31636620},
  reportid     = {RWTH-2020-01913},
  url          = {https://publications.rwth-aachen.de/record/782496},
  volume       = {10},
}

@article{Cullaro:834282,
  author       = {Cullaro, Giuseppe and Sharma, Rajani and Trebicka, Jonel and Cárdenas, Andrés and Verna, Elizabeth C.},
  title        = {Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes},
  journaltitle = {Liver transplantation},
  year         = {2019},
  doi          = {10.1002/lt.25678},
  keywords     = {,CRC1382-Project A09},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {283--293},
  publisher    = {Wiley},
  pubmed       = {pmid:31714011},
  reportid     = {RWTH-2021-09769},
  url          = {https://publications.rwth-aachen.de/record/834282},
  volume       = {26},
}

@article{Desalegn:786040,
  author       = {Desalegn, Girmay and Pabst, Oliver},
  title        = {Inflammation triggers immediate rather than progressive changes in monocyte differentiation in the small intestine},
  journaltitle = {Nature Communications},
  year         = {2019},
  doi          = {10.1038/s41467-019-11148-2},
  keywords     = {,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {3229},
  publisher    = {Nature Publishing Group UK},
  pubmed       = {pmid:31324779},
  reportid     = {RWTH-CONV-241347},
  url          = {https://publications.rwth-aachen.de/record/786040},
  volume       = {10},
}

@article{Loosen:781130,
  author       = {Loosen, Sven and Schulze-Hagen, Maximilian Franz and Bruners, Philipp and Tacke, Frank and Trautwein, Christian and Kuhl, Christiane K. and Lüdde, Tom and Roderburg, Christoph},
  title        = {Sarcopenia Is a Negative Prognostic Factor in Patients Undergoing Transarterial Chemoembolization ({TACE}) for Hepatic Malignancies},
  journaltitle = {Cancers},
  year         = {2019},
  doi          = {10.3390/cancers11101503},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {1503},
  publisher    = {MDPI},
  pubmed       = {pmid:31597337},
  reportid     = {RWTH-2020-01099},
  url          = {https://publications.rwth-aachen.de/record/781130},
  volume       = {11},
}

@article{Queck:815756,
  author       = {Queck, Alexander and Thomas, Dominique and Jansen, Christian and Schreiber, Yannick and Rüschenbaum, Sabrina and Praktiknjo, Michael and Schwarzkopf, Katharina Maria and Mücke, Marcus Maximilian and Schierwagen, Robert and Uschner, Frank Erhard and Meyer, Carsten and Clària, Joan and Zeuzem, Stefan and Geisslinger, Gerd and Trebicka, Jonel and Lange, Christian Markus},
  title        = {Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis},
  journaltitle = {PLOS ONE},
  year         = {2019},
  doi          = {10.1371/journal.pone.0222840},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09},
  location     = {San Francisco, California, US},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {e0222840},
  publisher    = {PLOS},
  pubmed       = {pmid:31644538},
  reportid     = {RWTH-2021-02820},
  url          = {https://publications.rwth-aachen.de/record/815756},
  volume       = {14},
}

@article{Sutti:784588,
  author          = {Sutti, Salvatore and Bruzzì, Stefania and Heymann, Felix and Liepelt, Anke and Krenkel, Oliver and Toscani, Alberto and Ramavath, Naresh and Cotella, Diego and Albano, Emanuele and Tacke, Frank},
  title           = {{CX}3{CR}1 Mediates the Development of Monocyte-Derived Dendritic Cells during Hepatic Inflammation},
  journaltitle    = {Cells},
  year            = {2019},
  doi             = {10.3390/cells8091099},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {9},
  pages           = {1099},
  publisher       = {MDPI},
  pubmed          = {pmid:31540356},
  reportid        = {RWTH-2020-02635},
  url             = {https://publications.rwth-aachen.de/record/784588},
  volume          = {8},
}

@article{Bartneck:803964,
  author       = {Bartneck, Matthias and Koppe, Christiane and Fech, Viktor and Warzecha, Klaudia Theresa and Kohlhepp, Marlene and Huss, Sebastian and Weiskirchen, Ralf and Trautwein, Christian and Lüdde, Tom and Tacke, Frank},
  title        = {Roles of {CCR}2 and {CCR}5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific {NEMO} Deletion},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2020},
  doi          = {10.1016/j.jcmgh.2020.08.012},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {327--347},
  publisher    = {Elsevier},
  pubmed       = {pmid:32896623},
  reportid     = {RWTH-CONV-242688},
  shortjournal = {CMGH},
  url          = {https://publications.rwth-aachen.de/record/803964},
  volume       = {11},
}

@article{Benz:813492,
  author       = {Benz, Fabian and Bogen, Andreas and Praktiknjo, Michael and Jansen, Christian and Meyer, Carsten and Wree, Alexander and Demir, Muenevver and Loosen, Sven and Vucur, Mihael and Schierwagen, Robert and Tacke, Frank and Trebicka, Jonel and Roderburg, Christoph},
  title        = {Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis},
  journaltitle = {PLOS ONE},
  year         = {2020},
  doi          = {10.1371/journal.pone.0231701},
  keywords     = {,CRC1382-Project A09,CRC1382-Project B05,CRC1382-Project A09},
  location     = {San Francisco, California, US},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {e0231701},
  publisher    = {PLOS},
  pubmed       = {pmid:32302330},
  reportid     = {RWTH-CONV-244453},
  url          = {https://publications.rwth-aachen.de/record/813492},
  volume       = {15},
}

@article{vanBest:793496,
  author       = {van Best, Niels and Rolle-Kampczyk, U. and Schaap, Frank G. and Basic, M. and Olde Damink, Steven W. M. and Bleich, A. and Savelkoul, P. and von Bergen, Martin and Penders, J. and Hornef, Mathias W.},
  title        = {Bile acids drive the newborn’s gut microbiota maturation},
  journaltitle = {Nature Communications},
  year         = {2020},
  doi          = {10.1038/s41467-020-17183-8},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project A07,CRC1382-Project A07,CRC1382-Project A05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {3692},
  publisher    = {Nature Publishing Group UK},
  pubmed       = {pmid:32703946},
  reportid     = {RWTH-2020-06966},
  url          = {https://publications.rwth-aachen.de/record/793496},
  volume       = {11},
}

@article{vanBest:812236,
  author       = {van Best, Niels and Trepels-Kottek, Sonja and Savelkoul, Paul and Orlikowsky, Thorsten and Hornef, Mathias W. and Penders, John},
  title        = {Influence of probiotic supplementation on the developing microbiota in human preterm neonates},
  journaltitle = {Gut microbes},
  year         = {2020},
  doi          = {10.1080/19490976.2020.1826747},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Austin, Tex.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1826747},
  publisher    = {Landes Bioscience},
  pubmed       = {pmid:33095113},
  reportid     = {RWTH-2021-01755},
  url          = {https://publications.rwth-aachen.de/record/812236},
  volume       = {12},
}

@article{Biancacci:813421,
  author       = {Biancacci, Ilaria and Sun, Qingxue and Möckel, Diana and Gremse, Felix and Rosenhain, Stefanie and Kießling, Fabian and Bartneck, Matthias and Hu, Qizhi and Thewissen, Marielle and Storm, Gert and Hennink, Wim E. and Shi, Yang and Rijcken, Cristianne J. F. and Lammers, Twan and Sofias, Alexandros Marios},
  title        = {Optical imaging of the whole-body to cellular biodistribution of clinical-stage {PEG}-b-p{HPMA}-based core-crosslinked polymeric micelles},
  journaltitle = {Journal of controlled release},
  year         = {2020},
  doi          = {10.1016/j.jconrel.2020.09.046},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {New York, NY and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {805--816},
  publisher    = {Elsevier},
  pubmed       = {pmid:33010332},
  reportid     = {RWTH-CONV-244383},
  url          = {https://publications.rwth-aachen.de/record/813421},
  volume       = {328},
}

@article{Bossert:788839,
  author       = {Bossert, Lukas C.},
  title        = {Mit »biber --tool« Bibliografieeinträge bearbeiten},
  journaltitle = {Die TEXnische Komödie},
  year         = {2020},
  doi          = {10.5281/zenodo.3784922},
  keywords     = {,CRC1382-Project Q04},
  location     = {Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {24--33},
  publisher    = {DANTE},
  reportid     = {RWTH-2020-04796},
  url          = {https://publications.rwth-aachen.de/record/788839},
  volume       = {2},
}

@article{Buendgens:803962,
  author       = {Buendgens, Lukas and Yagmur, Eray and Ginsberg, Axel and Weiskirchen, Ralf and Wirtz, Theresa and Jhaisha, Samira Abu and Eisert, Albrecht and Lüdde, Tom and Trautwein, Christian and Tacke, Frank and Koch, Alexander},
  title        = {Midregional Proadrenomedullin ({MR}pro{ADM}) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up},
  journaltitle = {Mediators of inflammation},
  year         = {2020},
  doi          = {10.1155/2020/7184803},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Sylvania, Ohio},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {7184803},
  publisher    = {Hindawi Publishing Corp.},
  pubmed       = {pmid:32831638},
  reportid     = {RWTH-CONV-242687},
  url          = {https://publications.rwth-aachen.de/record/803962},
  volume       = {2020},
}

@article{Cremonese:803969,
  author       = {Cremonese, Carla and Schierwagen, Robert and Uschner, Frank Erhard and Torres, Sandra and Tyc, Olaf and Ortiz, Cristina and Schulz, Martin and Queck, Alexander and Kristiansen, Glen and Bader, Michael and Sauerbruch, Tilman and Weiskirchen, Ralf and Walther, Thomas and Trebicka, Jonel and Klein, Sabine},
  title        = {Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease ({NAFLD}) With Portal Hypertension in {TGR}(m{REN}2)27 Rats},
  journaltitle = {International journal of molecular sciences},
  year         = {2020},
  doi          = {10.3390/ijms21093308},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09,CRC1382-Project A09},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {3308},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:32392802},
  reportid     = {RWTH-CONV-242685},
  url          = {https://publications.rwth-aachen.de/record/803969},
  volume       = {21},
}

@article{Drescher:789112,
  author          = {Drescher, Hannah K. and Schippers, Angela and Rosenhain, Stefanie and Gremse, Felix and Bongiovanni, Laura and de Bruin, Alain and Eswaran, Sreepradha and Gallage, Suchira U. and Pfister, Dominik and Szydlowska, Marta and Heikenwalder, Mathias and Weiskirchen, Sabine and Wagner, Norbert and Trautwein, Christian and Weiskirchen, Ralf and Kroy, Daniela C.},
  title           = {L-Selectin/{CD}62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men},
  journaltitle    = {Cells},
  year            = {2020},
  doi             = {10.3390/cells9051106},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B02,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project B02,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project B02},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {5},
  pages           = {1106},
  publisher       = {MDPI},
  pubmed          = {pmid:32365632},
  reportid        = {RWTH-2020-05002},
  url             = {https://publications.rwth-aachen.de/record/789112},
  volume          = {9},
}

@article{Echle:813402,
  author          = {Echle, Amelie and Grabsch, Heike Irmgard and Quirke, Philip and van den Brandt, Piet A. and West, Nicholas P. and Hutchins, Gordon G. A. and Heij, Lara R. and Tan, Xiuxiang and Richman, Susan D. and Krause, Jeremias and Alwers, Elizabeth and Jenniskens, Josien and Offermans, Kelly and Gray, Richard and Brenner, Hermann and Chang-Claude, Jenny and Trautwein, Christian and Pearson, Alexander T. and Boor, Peter and Lüdde, Tom and Gaisa, Nadine Therese and Hoffmeister, Michael and Kather, Jakob Nikolas},
  title           = {Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning},
  journaltitle    = {Gastroenterology},
  year            = {2020},
  doi             = {10.1053/j.gastro.2020.06.021},
  journalsubtitle = {Official publication of the American Gastroenterological Association},
  keywords        = {,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Philadelphia, Pa. and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {1406--1416.e11},
  publisher       = {Saunders},
  pubmed          = {pmid:32562722},
  reportid        = {RWTH-CONV-244366},
  url             = {https://publications.rwth-aachen.de/record/813402},
  volume          = {159},
}

@article{GanalVonarburg:793457,
  author       = {Ganal-Vonarburg, Stephanie C. and Hornef, Mathias W. and Macpherson, Andrew J.},
  title        = {Microbial-host molecular exchange and its functional consequences in early mammalian life},
  journaltitle = {Science / Science now},
  year         = {2020},
  doi          = {10.1126/science.aba0478},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6491},
  pages        = {604--607},
  publisher    = {American Association for the Advancement of Science},
  pubmed       = {pmid:32381716},
  reportid     = {RWTH-2020-06936},
  url          = {https://publications.rwth-aachen.de/record/793457},
  volume       = {368},
}

@article{Guillot:808892,
  author       = {Guillot, Adrien and Kohlhepp, Marlene S. and Bruneau, Alix and Heymann, Felix and Tacke, Frank},
  title        = {Deciphering the Immune Microenvironment on A Single Archival Formalin-Fixed Paraffin-Embedded Tissue Section by An Immediately Implementable Multiplex Fluorescence Immunostaining Protocol},
  journaltitle = {Cancers},
  year         = {2020},
  doi          = {10.3390/cancers12092449},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {2449},
  publisher    = {MDPI},
  reportid     = {RWTH-2020-12370},
  url          = {https://publications.rwth-aachen.de/record/808892},
  volume       = {12},
}

@article{Guillot:791928,
  author          = {Guillot, Adrien and Tacke, Frank},
  title           = {The Unexpected Role of Neutrophils for Resolving Liver Inflammation by Transmitting Micro{RNA}‐223 to Macrophages},
  journaltitle    = {Hepatology},
  year            = {2020},
  doi             = {10.1002/hep.30925},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05,CRC1382-Project B05},
  location        = {New York and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {749--751},
  publisher       = {Wiley Interscience},
  pubmed          = {pmid:31483871},
  reportid        = {RWTH-2020-05709},
  url             = {https://publications.rwth-aachen.de/record/791928},
  volume          = {71},
}

@article{Holmar:807156,
  author          = {Holmar, Jana and de la Puente-Secades, Sofía and Flöge, Jürgen and Noels, Heidi and Jankowski, Joachim and Orth-Alampour, Setareh},
  title           = {Uremic Toxins Affecting Cardiovascular Calcification},
  journaltitle    = {Cells},
  year            = {2020},
  doi             = {10.3390/cells9112428},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A04,CRC1382-Project A04},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {11},
  pages           = {2428},
  publisher       = {MDPI},
  pubmed          = {pmid:33172085},
  reportid        = {RWTH-2020-11157},
  subtitle        = {A Systematic Review},
  url             = {https://publications.rwth-aachen.de/record/807156},
  volume          = {9},
}

@article{Hornef:781397,
  author          = {Hornef, Mathias W. and Torow, Natalia},
  title           = {‘Layered immunity’ and the ‘neonatal window of opportunity’ - timed succession of non-redundant phases to establish mucosal host-microbial homeostasis after birth},
  journaltitle    = {Immunology},
  year            = {2020},
  doi             = {10.1111/imm.13149},
  journalsubtitle = {An official journal of the British Society for Immunology},
  keywords        = {,CRC1382-Project B01,CRC1382-Project Q03},
  location        = {Oxford and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {1},
  pages           = {15--25},
  publisher       = {Wiley-Blackwell},
  pubmed          = {pmid:31777069},
  reportid        = {RWTH-2020-01251},
  url             = {https://publications.rwth-aachen.de/record/781397},
  volume          = {159},
}

@article{Hundertmark:815766,
  author       = {Hundertmark, Jana and Tacke, Frank},
  title        = {How effective are nonalcoholic fatty liver disease models for drug discovery?},
  journaltitle = {Expert opinion on drug discovery},
  year         = {2020},
  doi          = {10.1080/17460441.2020.1776258},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {1237--1240},
  publisher    = {Taylor \& Francis Group},
  reportid     = {RWTH-2021-02829},
  url          = {https://publications.rwth-aachen.de/record/815766},
  volume       = {15},
}

@article{Kabbert:794137,
  author       = {Kabbert, Johanna and Benckert, Julia and Rollenske, Tim and Hitch, Thomas C. A. and Clavel, Thomas and Cerovic, Vuk and Wardemann, Hedda and Pabst, Oliver},
  title        = {High microbiota reactivity of adult human intestinal IgA requires somatic mutations},
  journaltitle = {Journal of experimental medicine},
  year         = {2020},
  doi          = {10.1084/jem.20200275},
  keywords     = {,CRC1382-Project B03,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B06,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {e20200275},
  publisher    = {Rockefeller Univ. Press},
  pubmed       = {pmid:32640466},
  reportid     = {RWTH-2020-07429},
  shortjournal = {JEM},
  url          = {https://publications.rwth-aachen.de/record/794137},
  volume       = {217},
}

@article{Kather:855673,
  author       = {Kather, Jakob Nikolas and Heij, Lara R. and Grabsch, Heike I. and Loeffler, Chiara and Echle, Amelie and Muti, Hannah Sophie and Krause, Jeremias and Niehues, Jan M. and Sommer, Kai A. J. and Bankhead, Peter and Kooreman, Loes F. S. and Schulte, Jefree J. and Cipriani, Nicole A. and Buelow, Roman D. and Boor, Peter and Ortiz-Brüchle, Nadina and Hanby, Andrew M. and Speirs, Valerie and Kochanny, Sara and Patnaik, Akash and Srisuwananukorn, Andrew and Brenner, Hermann and Hoffmeister, Michael and van den Brandt, Piet A. and Jäger, Dirk and Trautwein, Christian and Pearson, Alexander T. and Lüdde, Tom},
  title        = {Pan-cancer image-based detection of clinically actionable genetic alterations},
  journaltitle = {Nature cancer},
  year         = {2020},
  doi          = {10.1038/s43018-020-0087-6},
  keywords     = {,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {789--799},
  publisher    = {Nature Research},
  pubmed       = {pmid:33763651},
  reportid     = {RWTH-2022-10354},
  url          = {https://publications.rwth-aachen.de/record/855673},
  volume       = {1},
}

@article{Klein:791931,
  author       = {Klein, Leah Maria and Chang, Johannes and Gu, Wenyi and Manekeller, Steffen and Jansen, Christian and Lingohr, Philipp and Praktiknjo, Michael and Kalf, Jörg C. and Schulz, Martin and Spengler, Ulrich and Strassburg, Christian and Cárdenas, Andrés and Arroyo, Vicente and Trebicka, Jonel},
  title        = {The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions},
  journaltitle = {Liver transplantation},
  year         = {2020},
  doi          = {10.1002/lt.25675},
  keywords     = {,CRC1382-Project A09},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {227--237},
  publisher    = {Wiley},
  pubmed       = {pmid:31693788},
  reportid     = {RWTH-2020-05712},
  url          = {https://publications.rwth-aachen.de/record/791931},
  volume       = {26},
}

@article{LamasPaz:809360,
  author       = {Lamas-Paz, Arantza and Morán, Laura and Peng, Jin and Salinas, Beatriz and López-Alcántara, Nuria and Sydor, Svenja and Vilchez-Vargas, Ramiro and Asensio, Iris and Hao, Fengjie and Zheng, Kang and Martín-Adrados, Beatriz and Moreno, Laura and Cogolludo, Angel and Gómez del Moral, Manuel and Bechmann, Lars and Martínez-Naves, Eduardo and Vaquero, Javier and Bañares, Rafael and Nevzorova, Yulia A. and Cubero, Francisco Javier},
  title        = {Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury},
  journaltitle = {Frontiers in pharmacology},
  year         = {2020},
  doi          = {10.3389/fphar.2020.603771},
  keywords     = {,CRC1382-Project A02},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {603771},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:33408632},
  reportid     = {RWTH-2021-00007},
  url          = {https://publications.rwth-aachen.de/record/809360},
  volume       = {11},
}

@article{Lambrecht:828487,
  author       = {Lambrecht, Joeri and van Grunsven, Leo A. and Tacke, Frank},
  title        = {Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis},
  journaltitle = {Expert opinion on pharmacotherapy},
  year         = {2020},
  doi          = {10.1080/14656566.2020.1774553},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {13},
  pages        = {1637--1650},
  publisher    = {Routledge, Taylor \& Francis},
  reportid     = {RWTH-2021-09139},
  shortjournal = {EOP},
  url          = {https://publications.rwth-aachen.de/record/828487},
  volume       = {21},
}

@article{Lefere:788068,
  author       = {Lefere, Sander and Devisscher, Lindsey and Tacke, Frank},
  title        = {Targeting {CCR}2/5 in the treatment of nonalcoholic steatohepatitis ({NASH}) and fibrosis},
  journaltitle = {Expert opinion on investigational drugs},
  year         = {2020},
  doi          = {10.1080/13543784.2020.1718106},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {89--92},
  publisher    = {Routledge, Taylor \& Francis},
  pubmed       = {pmid:31952447},
  reportid     = {RWTH-2020-04416},
  subtitle     = {Opportunities and challenges},
  url          = {https://publications.rwth-aachen.de/record/788068},
  volume       = {29},
}

@article{Lefere:813502,
  author       = {Lefere, Sander and Püngel, Tobias and Hundertmark, Jana and Penners, Christian and Frank, Anna Katharina and Guillot, Adrien and de Muynck, Kevin and Heymann, Felix and Adarbes, Vanessa and Defrêne, Evelyne and Estivalet, Céline and Geerts, Anja and Devisscher, Lindsey and Wettstein, Guillaume and Tacke, Frank},
  title        = {Differential effects of selective- and pan-{PPAR} agonists on experimental steatohepatitis and hepatic macrophages},
  journaltitle = {Journal of hepatology},
  year         = {2020},
  doi          = {10.1016/j.jhep.2020.04.025},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {757--770},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:32360434},
  reportid     = {RWTH-CONV-244470},
  url          = {https://publications.rwth-aachen.de/record/813502},
  volume       = {73},
}

@article{Lenicek:807181,
  author          = {Lenicek, Martin and Olde Damink, Steven W. M. and Schaap, Frank G.},
  title           = {Gut Microbes Take It to the Next Level?},
  journaltitle    = {Hepatology},
  year            = {2020},
  doi             = {10.1002/hep.31455},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project A07,CRC1382-Project A07},
  location        = {New York and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {1483--1485},
  publisher       = {Wiley Interscience},
  pubmed          = {pmid:32648608},
  reportid        = {RWTH-2020-11172},
  subtitle        = {First Insights Into Farnesoid X Receptor Agonists of Microbial Origin},
  url             = {https://publications.rwth-aachen.de/record/807181},
  volume          = {72},
}

@article{Lesker:796359,
  author       = {Lesker, Till R. and Durairaj, Abilash C. and Gálvez, Eric J. C. and Lagkouvardos, Ilias and Baines, John F. and Clavel, Thomas and Sczyrba, Alexander and McHardy, Alice C. and Strowig, Till},
  title        = {An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome},
  journaltitle = {Cell reports},
  year         = {2020},
  doi          = {10.1016/j.celrep.2020.02.036},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {2909--2922.e6},
  publisher    = {Elsevier},
  pubmed       = {pmid:32130896},
  reportid     = {RWTH-2020-08943},
  url          = {https://publications.rwth-aachen.de/record/796359},
  volume       = {30},
}

@article{Liepelt:788069,
  author       = {Liepelt, Anke and Hohlstein, Philipp and Gussen, Hendrik and Xue, Jia and Aschenbrenner, Anna C. and Ulas, Thomas and Bündgens, Lukas and Warzecha, Klaudia Theresa and Bartneck, Matthias and Lüdde, Tom and Trautwein, Christian and Schultze, Joachim L. and Koch, Alexander and Tacke, Frank},
  title        = {Differential Gene Expression in Circulating {CD}14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2020},
  doi          = {10.3390/jcm9010127},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {127},
  publisher    = {MDPI},
  pubmed       = {pmid:31906585},
  reportid     = {RWTH-2020-04417},
  url          = {https://publications.rwth-aachen.de/record/788069},
  volume       = {9},
}

@article{Lurje:815761,
  author       = {Lurje, Isabella and Hammerich, Linda and Tacke, Frank},
  title        = {Dendritic Cell and T Cell Crosstalk in Liver Fibrogenesis and Hepatocarcinogenesis: Implications for Prevention and Therapy of Liver Cancer},
  journaltitle = {International journal of molecular sciences},
  year         = {2020},
  doi          = {10.3390/ijms21197378},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {19},
  pages        = {7378},
  publisher    = {Molecular Diversity Preservation International},
  reportid     = {RWTH-2021-02825},
  url          = {https://publications.rwth-aachen.de/record/815761},
  volume       = {21},
}

@article{Mendler:791935,
  author       = {Mendler, A. and Pierzchalski, A. and Bauer, M. and Röder, S. and Sattler, A. and Standl, M. and Borte, M. and von Bergen, Martin and Rolle-Kampczyk, U. and Herberth, G.},
  title        = {{MAIT} cell activation in adolescents is impacted by bile acid concentrations and body weight},
  journaltitle = {Clinical and experimental immunology},
  year         = {2020},
  doi          = {10.1111/cei.13423},
  keywords     = {,CRC1382-Project A05},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {199--213},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:32012235},
  reportid     = {RWTH-2020-05716},
  url          = {https://publications.rwth-aachen.de/record/791935},
  volume       = {200},
}

@article{Mossanen:788070,
  author       = {Mossanen, Jana C. and Jansen, Tobias U. and Pracht, Jessica and Liepelt, Anke and Bündgens, Lukas and Stoppe, Christian and Goetzenich, Andreas and Simon, Tim-Philipp and Autschbach, Rüdiger and Marx, Gernot and Tacke, Frank},
  title        = {Elevated circulating {CD}14++{CD}16+ intermediate monocytes are independently associated with extracardiac complications after cardiac surgery},
  journaltitle = {Scientific reports},
  year         = {2020},
  doi          = {10.1038/s41598-020-57700-9},
  keywords     = {,CRC1382-Project B05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {947},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  pubmed       = {pmid:31969629},
  reportid     = {RWTH-2020-04418},
  url          = {https://publications.rwth-aachen.de/record/788070},
  volume       = {10},
}

@article{Pabst:780352,
  author       = {Pabst, Oliver and Slack, Emma},
  title        = {IgA and the intestinal microbiota},
  journaltitle = {Mucosal immunology},
  year         = {2020},
  doi          = {10.1038/s41385-019-0227-4},
  keywords     = {,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {12--21},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:31740744},
  reportid     = {RWTH-2020-00580},
  subtitle     = {The importance of being specific},
  url          = {https://publications.rwth-aachen.de/record/780352},
  volume       = {13},
}

@article{Pereira:803881,
  author       = {Pereira, Fátima C. and Wasmund, Kenneth and Cobankovic, Iva and Jehmlich, Nico and Herbold, Craig W. and Lee, Kang Soo and Sziranyi, Barbara and Vesely, Cornelia and Decker, Thomas and Stocker, Roman and Warth, Benedikt and von Bergen, Martin and Wagner, Michael and Berry, David},
  title        = {Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization},
  journaltitle = {Nature Communications},
  year         = {2020},
  doi          = {10.1038/s41467-020-18928-1},
  keywords     = {,CRC1382-Project A05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {5104},
  publisher    = {Nature Publishing Group UK},
  reportid     = {RWTH-2020-09942},
  url          = {https://publications.rwth-aachen.de/record/803881},
  volume       = {11},
}

@article{Pieper:812434,
  author       = {Pieper, Robert and van Best, Niels and van Vorst, Kira and Ebner, Friederike and Reissmann, Monika and Hornef, Mathias W. and Fulde, Marcus},
  title        = {Toward a porcine in vivo model to analyze the pathogenesis of {TLR}5-dependent enteropathies},
  journaltitle = {Gut microbes},
  year         = {2020},
  doi          = {10.1080/19490976.2020.1782163},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Austin, Tex.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1782163},
  publisher    = {Landes Bioscience},
  pubmed       = {pmid:32715918},
  reportid     = {RWTH-CONV-243395},
  url          = {https://publications.rwth-aachen.de/record/812434},
  volume       = {12},
}

@article{Pngel:791898,
  author       = {Püngel, Tobias and De Vos, Steve and Hundertmark, Jana and Kohlhepp, Marlene and Guldiken, Nurdan and Pujuguet, Philippe and Auberval, Marielle and Marsais, Florence and Shoji, Kenji F. and Saniere, Laurent and Trautwein, Christian and Lüdde, Tom and Strnad, Pavel and Brys, Reginald and Clément-Lacroix, Philippe and Tacke, Frank},
  title        = {The medium-chain fatty acid receptor gpr84 mediates myeloid cell infiltration promoting steatohepatitis and fibrosis},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2020},
  doi          = {10.3390/jcm9041140},
  keywords     = {,CRC1382-Project A03,CRC1382-Project A01,CRC1382-Project A03,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {1140},
  publisher    = {MDPI},
  pubmed       = {pmid:32316235},
  reportid     = {RWTH-2020-05683},
  url          = {https://publications.rwth-aachen.de/record/791898},
  volume       = {9},
}

@article{Pngel:828593,
  author       = {Püngel, Tobias and Tacke, Frank},
  title        = {Editorial: prevalence, progression rates and mortality predictors of non-alcoholic fatty liver disease reflected by German statutory health insurance data},
  journaltitle = {Alimentary pharmacology \& therapeutics},
  year         = {2020},
  doi          = {10.1111/apt.16077},
  keywords     = {,CRC1382-Project B05},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1412--1413},
  publisher    = {Blackwell Science},
  pubmed       = {pmid:33105983},
  reportid     = {RWTH-2021-09218},
  url          = {https://publications.rwth-aachen.de/record/828593},
  volume       = {52},
}

@article{Queck:813493,
  author       = {Queck, Alexander and Bode, Hannah and Uschner, Frank E. and Brol, Maximilian J. and Graf, Christiana and Schulz, Martin and Jansen, Christian and Praktiknjo, Michael and Schierwagen, Robert and Klein, Sabine and Trautwein, Christian and Wasmuth, Hermann Elard and Berres, Marie-Luise and Trebicka, Jonel and Lehmann, Jennifer},
  title        = {Systemic {MCP}-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis},
  journaltitle = {Frontiers in immunology},
  year         = {2020},
  doi          = {10.3389/fimmu.2020.00354},
  keywords     = {,CRC1382-Project B04,CRC1382-Project A09,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A09},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {354},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:32218781},
  reportid     = {RWTH-CONV-244454},
  url          = {https://publications.rwth-aachen.de/record/813493},
  volume       = {11},
}

@article{Reimer:780555,
  author       = {Reimer, Katharina Charlotte and Wree, Alexander and Roderburg, Christoph and Tacke, Frank},
  title        = {New drugs for {NAFLD}},
  journaltitle = {Hepatology international},
  year         = {2020},
  doi          = {10.1007/s12072-019-10001-4},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {8--23},
  publisher    = {Springer},
  pubmed       = {pmid:31802390},
  reportid     = {RWTH-2020-00722},
  subtitle     = {Lessons from basic models to the clinic},
  url          = {https://publications.rwth-aachen.de/record/780555},
  volume       = {14},
}

@article{Riba:793498,
  author       = {Riba, Ambre and Hassani, Kasra and Walker, Alesia and van Best, Niels and von Zeschwitz, Dunja and Anslinger, Teresa and Sillner, Nina and Rosenhain, Stefanie and Eibach, Daniel and Maiga-Ascofaré, Oumou and Rolle-Kampczyk, Ulrike and Basic, Marijana and Binz, Anne and Mocek, Sabine and Sodeik, Beate and Bauerfeind, Rudolf and Mohs, Antje and Trautwein, Christian and Kießling, Fabian and May, Jürgen and Klingenspor, Martin and Gremse, Felix and Schmitt-Kopplin, Philippe and Bleich, André and Torow, Natalia and von Bergen, Martin and Hornef, Mathias W.},
  title        = {Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment},
  journaltitle = {Science translational medicine},
  year         = {2020},
  doi          = {10.1126/scitranslmed.aay7019},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A05},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {565},
  pages        = {eaay7019},
  publisher    = {AAAS},
  pubmed       = {pmid:33055245},
  reportid     = {RWTH-2020-06967},
  url          = {https://publications.rwth-aachen.de/record/793498},
  volume       = {12},
}

@article{Roderburg:788071,
  author       = {Roderburg, Christoph and Wree, Alexander and Demir, Münevver and Schmelzle, Moritz and Tacke, Frank},
  title        = {The role of the innate immune system in the development and treatment of hepatocellular carcinoma},
  journaltitle = {Hepatic Oncology},
  year         = {2020},
  doi          = {10.2217/hep-2019-0007},
  keywords     = {,CRC1382-Project B05},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {11 Seiten},
  publisher    = {Future Medicine},
  pubmed       = {pmid:32273975},
  reportid     = {RWTH-2020-04419},
  url          = {https://publications.rwth-aachen.de/record/788071},
  volume       = {7},
}

@article{Schierwagen:834280,
  author       = {Schierwagen, Robert and Dietrich, Peter and Klein, Sabine and Uschner, Frank Erhard and Ortiz, Cristina and Tyc, Olaf and Torres, Sandra and Hellerbrand, Claus and Sauerbruch, Tilman and Trebicka, Jonel},
  title        = {β-Arrestin2 is increased in liver fibrosis in humans and rodents},
  journaltitle = {Proceedings of the National Academy of Sciences of the United States of America},
  year         = {2020},
  doi          = {10.1073/pnas.2014337117},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09,CRC1382-Project A09},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {44},
  pages        = {27082--27084},
  publisher    = {National Acad. of Sciences},
  pubmed       = {pmid:33144522},
  reportid     = {RWTH-2021-09767},
  url          = {https://publications.rwth-aachen.de/record/834280},
  volume       = {117},
}

@article{Schierwagen:815762,
  author       = {Schierwagen, Robert and Uschner, Frank E. and Ortiz, Cristina and Torres, Sandra and Brol, Max J. and Tyc, Olaf and Gu, Wenyi and Grimm, Christian and Zeuzem, Stefan and Plamper, Andreas and Pfeifer, Philipp and Zimmer, Sebastian and Welsch, Christoph and Schaefer, Liliana and Rheinwalt, Karl P. and Clària, Joan and Arroyo, Vicente and Trebicka, Jonel and Klein, Sabine},
  title        = {The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease},
  journaltitle = {Frontiers in immunology},
  year         = {2020},
  doi          = {10.3389/fimmu.2020.01352},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09,CRC1382-Project A09},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1352},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2021-02826},
  url          = {https://publications.rwth-aachen.de/record/815762},
  volume       = {11},
}

@article{Schwarzkopf:834281,
  author       = {Schwarzkopf, Katharina Maria and Eberle, Larissa and Uschner, Frank Erhard and Klein, Sabine and Schierwagen, Robert and Mücke, Marcus Maximilian and Schaefer, Liliana and Clària, Joan and Zeuzem, Stefan and Hintermann, Edith and Christen, Urs and Lange, Christian Markus and Trebicka, Jonel and Welsch, Christoph},
  title        = {Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling?},
  journaltitle = {Journal of hepatology},
  year         = {2020},
  doi          = {10.1016/j.jhep.2020.05.012},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {980--982},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:32698966},
  reportid     = {RWTH-2021-09768},
  url          = {https://publications.rwth-aachen.de/record/834281},
  volume       = {73},
}

@article{Thiele:791933,
  author       = {Thiele, Maja and Hugger, Mie Balle and Kim, Yongsoo and Rautou, Pierre-Emmanuel and Elkrief, Laure and Jansen, Christian and Verlinden, Wim and Allegretti, Giulia and Israelsen, Mads and Stefanescu, Horia and Piscaglia, Fabio and García-Pagán, Juan Carlos and Franque, Sven and Berzigotti, Annalisa and Castera, Laurent and Jeong, Woo Kyoung and Trebicka, Jonel and Krag, Aleksander},
  title        = {2D shear wave liver elastography by aixplorer to detect portal hypertension in cirrhosis: an individual patient data meta-analysis},
  journaltitle = {Liver international},
  year         = {2020},
  doi          = {10.1111/liv.14439},
  keywords     = {,CRC1382-Project A09},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {1435--1446},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:32180327},
  reportid     = {RWTH-2020-05714},
  url          = {https://publications.rwth-aachen.de/record/791933},
  volume       = {40},
}

@article{Torres:787066,
  author       = {Torres, Sandra and Abdullah, Zeinab and Brol, Maximilian J. and Hellerbrand, Claus and Fernandez, Mercedes and Fiorotto, Romina and Klein, Sabine and Königshofer, Philipp and Liedtke, Christian and Lotersztajn, Sophie and Nevzorova, Yulia A. and Schierwagen, Robert and Reiberger, Thomas and Uschner, Frank Erhard and Tacke, Frank and Weiskirchen, Ralf and Trebicka, Jonel},
  title        = {Recent Advances in Practical Methods for Liver Cell Biology},
  journaltitle = {International journal of molecular sciences},
  year         = {2020},
  doi          = {10.3390/ijms21062027},
  keywords     = {,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project A09,CRC1382-Project B05,CRC1382-Project A09},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {2027},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:32188134},
  reportid     = {RWTH-2020-03874},
  subtitle     = {A Short Overview},
  url          = {https://publications.rwth-aachen.de/record/787066},
  volume       = {21},
}

@article{Wirtz:813391,
  author          = {Wirtz, Theresa and Buendgens, Lukas and Weiskirchen, Ralf and Loosen, Sven H. and Haehnsen, Nina and Puengel, Tobias and Abu Jhaisha, Samira and Brozat, Jonathan F. and Hohlstein, Philipp and Koek, Ger and Eisert, Albrecht and Mohr, Raphael and Roderburg, Christoph and Lüdde, Tom and Trautwein, Christian and Tacke, Frank and Koch, Alexander},
  title           = {Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients},
  journaltitle    = {Diagnostics},
  year            = {2020},
  doi             = {10.3390/diagnostics10110990},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {11},
  pages           = {990},
  publisher       = {MDPI},
  pubmed          = {pmid:33238644},
  reportid        = {RWTH-CONV-244354},
  url             = {https://publications.rwth-aachen.de/record/813391},
  volume          = {10},
}

@article{Wirtz:803971,
  author          = {Wirtz, Theresa and Loosen, Sven H. and Buendgens, Lukas and Kurt, Berkan and Abu Jhaisha, Samira and Hohlstein, Philipp and Brozat, Jonathan F. and Weiskirchen, Ralf and Lüdde, Tom and Tacke, Frank and Trautwein, Christian and Roderburg, Christoph and Koch, Alexander},
  title           = {Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients},
  journaltitle    = {Diagnostics},
  year            = {2020},
  doi             = {10.3390/diagnostics10080574},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {8},
  pages           = {574},
  publisher       = {MDPI},
  pubmed          = {pmid:32784522},
  reportid        = {RWTH-CONV-242698},
  url             = {https://publications.rwth-aachen.de/record/803971},
  volume          = {10},
}

@article{ZengBrouwers:815763,
  author       = {Zeng-Brouwers, Jinyang and Pandey, Sony and Trebicka, Jonel and Wygrecka, Malgorzata and Schaefer, Liliana},
  title        = {Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases},
  journaltitle = {Journal of histochemistry \& cytochemistry},
  year         = {2020},
  doi          = {10.1369/0022155420930303},
  keywords     = {,CRC1382-Project A09},
  location     = {Seattle, Wash.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {887--906},
  publisher    = {Histochemical Soc.},
  reportid     = {RWTH-2021-02827},
  url          = {https://publications.rwth-aachen.de/record/815763},
  volume       = {68},
}

@article{Baier:828360,
  author       = {Baier, Vanessa and Clayton, Olivia and Nudischer, Ramona and Cordes, Henrik and Schneider, Annika R. P. and Thiel, Christoph Werner Josef and Wittenberger, Timo and Moritz, Wolfgang and Blank, Lars Mathias and Neumann, Ulf Peter and Trautwein, Christian and Kelm, Jens and Schrooders, Yannick and Caiment, Florian and Gmuender, Hans and Roth, Adrian and Castell, José V. and Kleinjans, Jos and Küpfer, Lars Oliver},
  title        = {A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs},
  journaltitle = {Clinical pharmacology \& therapeutics},
  year         = {2021},
  doi          = {10.1002/cpt.2406},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A06,CRC1382-Project B08,CRC1382-Project A06,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {1293--1301},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:34462909},
  reportid     = {RWTH-2021-09100},
  shortjournal = {CPT},
  url          = {https://publications.rwth-aachen.de/record/828360},
  volume       = {110},
}

@article{Bednarsch:846344,
  author       = {Bednarsch, Jan and Czigany, Zoltan and Loosen, Sven and Heij, Lara and Ruckgaber, Lorenz and Maes, Henning and Krause, Jan-Pit and Reen, Matthias Werner and Toteva, Beata and Vosdellen, Theresa Katharina and Bruners, Philipp and Lang, Sven Arke and Ulmer, Tom Florian and Roderburg, Christoph and Lüdde, Tom and Neumann, Ulf Peter},
  title        = {Perioperative rifaximin is not associated with enhanced functional and volumetric recovery after major liver resection},
  journaltitle = {Scientific reports},
  year         = {2021},
  doi          = {10.1038/s41598-021-97442-w},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {17936},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  pubmed       = {pmid:34504196},
  reportid     = {RWTH-CONV-247756},
  url          = {https://publications.rwth-aachen.de/record/846344},
  volume       = {11},
}

@article{BenedUbieto:851417,
  author       = {Benedé-Ubieto, Raquel and Estévez-Vázquez, Olga and Guo, Feifei and Chen, Chaobo and Singh, Youvika and Nakaya, Helder I. and Gómez Del Moral, Manuel and Lamas-Paz, Arantza and Morán, Laura and López-Alcántara, Nuria and Reissing, Johanna and Bruns, Tony and Avila, Matías A. and Santamaría, Eva and Mazariegos, Marina S. and Woitok, Marius Maximilian and Haas, Ute and Zheng, Kang and Juárez, Ignacio and Martín-Villa, José Manuel and Asensio, Iris and Vaquero, Javier and Peligros, Maria Isabel and Argemi, Josepmaria and Bataller, Ramón and Ampuero, Javier and Romero Gómez, Manuel and Trautwein, Christian and Liedtke, Christian and Bañares, Rafael and Cubero, Francisco Javier and Nevzorova, Yulia A.},
  title        = {An Experimental {DUAL} Model of Advanced Liver Damage},
  journaltitle = {Hepatology communications},
  year         = {2021},
  doi          = {10.1002/hep4.1698},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {1051--1068},
  publisher    = {Wiley},
  pubmed       = {pmid:34141989},
  reportid     = {RWTH-CONV-248505},
  url          = {https://publications.rwth-aachen.de/record/851417},
  volume       = {5},
}

@article{Bruneau:855367,
  author       = {Bruneau, Alix and Hundertmark, Jana and Guillot, Adrien and Tacke, Frank},
  title        = {Molecular and Cellular Mediators of the Gut-Liver Axis in the Progression of Liver Diseases},
  journaltitle = {Frontiers in medicine},
  year         = {2021},
  doi          = {10.3389/fmed.2021.725390},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {725390},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2022-10184},
  url          = {https://publications.rwth-aachen.de/record/855367},
  volume       = {8},
}

@article{Detjen:855672,
  author       = {Detjen, Katharina M. and Otto, Raik and Giesecke, Yvonne and Geisler, Lukas and Riemer, Pamela and Jann, Henning and Grötzinger, Carsten and Sers, Christine and Pascher, Andreas and Lüdde, Tom and Leser, Ulf and Wiedenmann, Bertram and Sigal, Michael and Tacke, Frank and Roderburg, Christoph and Hammerich, Linda},
  title        = {Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms},
  journaltitle = {Cancers},
  year         = {2021},
  doi          = {10.3390/cancers13174463},
  keywords     = {,CRC1382-Project B05,CRC1382-Project A01,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {17},
  pages        = {4463},
  publisher    = {MDPI},
  pubmed       = {pmid:34503273},
  reportid     = {RWTH-2022-10353},
  url          = {https://publications.rwth-aachen.de/record/855672},
  volume       = {13},
}

@article{Echle:815758,
  author       = {Echle, Amelie and Rindtorff, Niklas Timon and Brinker, Titus Josef and Lüdde, Tom and Pearson, Alexander Thomas and Kather, Jakob Nikolas},
  title        = {Deep learning in cancer pathology: a new generation of clinical biomarkers},
  journaltitle = {British journal of cancer},
  year         = {2021},
  doi          = {10.1038/s41416-020-01122-x},
  keywords     = {,CRC1382-Project A01},
  location     = {Edinburgh},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {686--696},
  publisher    = {Nature Publ. Group},
  pubmed       = {pmid:33204028},
  reportid     = {RWTH-2021-02822},
  url          = {https://publications.rwth-aachen.de/record/815758},
  volume       = {124},
}

@article{EstvezVzquez:834526,
  author       = {Estévez-Vázquez, Olga and Benedé-Ubieto, Raquel and Guo, Feifei and Gómez-Santos, Beatriz and Aspichueta, Patricia and Reißing, Johanna and Bruns, Tony and Sanz-García, Carlos and Sydor, Svenja and Bechmann, Lars P. and Maranillo, Eva and Sañudo, José Ramón and Vázquez, María Teresa and Lamas-Paz, Arantza and Morán, Laura and Mazariegos, Marina S. and Ciudin, Andreea and Pericàs, Juan M. and Peligros, María Isabel and Vaquero, Javier and Martínez-Naves, Eduardo and Liedtke, Christian and Regueiro, José R. and Trautwein, Christian and Bañares, Rafael and Cubero, Francisco Javier and Nevzorova, Yulia A.},
  title        = {Fat},
  journaltitle = {Biomedicines},
  year         = {2021},
  doi          = {10.3390/biomedicines9101289},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {1289},
  publisher    = {MDPI},
  reportid     = {RWTH-2021-09968},
  subtitle     = {Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease ({MAFLD})},
  url          = {https://publications.rwth-aachen.de/record/834526},
  volume       = {9},
}

@article{Eswaran:823132,
  author       = {Eswaran, Sreepradha and Babbar, Anshu and Drescher, Hannah K. and Hitch, Thomas C. A. and Clavel, Thomas and Muschaweck, Moritz and Ritz, Thomas and Kroy, Daniela C. and Trautwein, Christian and Wagner, Norbert and Schippers, Angela},
  title        = {Upregulation of anti-oxidative stress response improves metabolic changes in l-selectin-deficient mice but does not prevent {NAFLD} progression or fecal microbiota shifts},
  journaltitle = {International journal of molecular sciences},
  year         = {2021},
  doi          = {10.3390/ijms22147314},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B02,CRC1382-Project B02,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project B02},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {14},
  pages        = {7314},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:34298930},
  reportid     = {RWTH-2021-07227},
  url          = {https://publications.rwth-aachen.de/record/823132},
  volume       = {22},
}

@article{Fulde:828376,
  author       = {Fulde, Marcus and van Vorst, Kira and Zhang, Kaiyi and Westermann, Alexander J. and Busche, Tobias and Huei, Yong Chiun and Welitschanski, Katharina and Froh, Isabell and Pägelow, Dennis and Plendl, Johanna and Pfarrer, Christiane and Kalinowski, Jörn and Vogel, Jörg and Valentin-Weigand, Peter and Hensel, Michael and Tedin, Karsten and Repnik, Urska and Hornef, Mathias W.},
  title        = {{SPI}2 T3{SS} effectors facilitate enterocyte apical to basolateral transmigration of Salmonella-containing vacuoles in vivo},
  journaltitle = {Gut microbes},
  year         = {2021},
  doi          = {10.1080/19490976.2021.1973836},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Austin, Tex.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1973836},
  publisher    = {Landes Bioscience},
  pubmed       = {pmid:34542008},
  reportid     = {RWTH-2021-09110},
  url          = {https://publications.rwth-aachen.de/record/828376},
  volume       = {13},
}

@article{Groe:848651,
  author       = {Große, K. and Ohm, D. and Würstle, S. and Brozat, J. F. and Schmid, R. M. and Trautwein, Christian and Stallmach, A. and Bruns, Tony and Reuken, Philipp A.},
  title        = {Clinical characteristics and outcome of patients with enterococcal liver abscess},
  journaltitle = {Scientific reports},
  year         = {2021},
  doi          = {10.1038/s41598-021-01620-9},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A06,CRC1382-Project A08},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {22265},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  pubmed       = {pmid:34782684},
  reportid     = {RWTH-2022-06190},
  url          = {https://publications.rwth-aachen.de/record/848651},
  volume       = {11},
}

@article{Gldiken:842993,
  author       = {Guldiken, Nurdan and Argemi, Josepmaria and Gurbuz, Berivan and Atkinson, Stephen R. and Oliverius, Martin and Fila, Petr and Hamesch, Karim and Bruns, Tony and Cabezas, Joaquín and Lozano, Juan J. and Mann, Jelena and Cao, Sheng and Mathurin, Philippe and Shah, Vijay H. and Trautwein, Christian and Thursz, Mark R. and Bataller, Ramon and Strnad, Pavel},
  title        = {Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases},
  journaltitle = {BMC medicine},
  year         = {2021},
  doi          = {10.1186/s12916-021-01917-6},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A03,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {39},
  publisher    = {BioMed Central},
  pubmed       = {pmid:33593348},
  reportid     = {RWTH-2022-02812},
  url          = {https://publications.rwth-aachen.de/record/842993},
  volume       = {19},
}

@article{Hausen:834321,
  author       = {Hausen, Daniela Adele and Bossert, Lukas C. and Trautwein-Bruns, Ute},
  title        = {Aufgaben- und Kompetenzspektrum der Data Stewards an der {RWTH} Aachen University},
  journaltitle = {Bausteine Forschungsdatenmanagement},
  year         = {2021},
  doi          = {10.17192/bfdm.2021.3.8352},
  keywords     = {,CRC1382-Project Q04},
  location     = {Marburg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {92--105},
  publisher    = {Philipps-Universität},
  reportid     = {RWTH-2021-09797},
  subtitle     = {Generell und explizit am Beispiel des Sonderforschungsbereichs 1382},
  url          = {https://publications.rwth-aachen.de/record/834321},
  volume       = {3},
}

@article{Heinrichs:811474,
  author          = {Heinrichs, Daniel and Brandt, Elisa Fabiana and Fischer, Petra and Köhncke, Janine and Wirtz, Theresa and Guldiken, Nurdan and Djudjaj, Sonja and Boor, Peter and Kroy, Daniela C. and Weiskirchen, Ralf and Bucala, Richard and Wasmuth, Hermann E. and Strnad, Pavel and Trautwein, Christian and Bernhagen, Jürgen and Berres, Marie-Luise},
  title           = {Unexpected Pro-Fibrotic Effect of {MIF} in Non-Alcoholic Steatohepatitis Is Linked to a Shift in {NKT} Cell Populations},
  journaltitle    = {Cells},
  year            = {2021},
  doi             = {10.3390/cells10020252},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B04,CRC1382-Project B04,CRC1382-Project A03,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {252},
  publisher       = {MDPI},
  pubmed          = {pmid:33525493},
  reportid        = {RWTH-2021-01211},
  url             = {https://publications.rwth-aachen.de/record/811474},
  volume          = {10},
}

@article{Henneke:828379,
  author       = {Henneke, Philipp and Kierdorf, Katrin and Hall, Lindsay J. and Sperandio, Markus and Hornef, Mathias W.},
  title        = {Perinatal development of innate immune topology},
  journaltitle = {eLife},
  year         = {2021},
  doi          = {10.7554/eLife.67793},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Cambridge},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {e67793},
  publisher    = {eLife Sciences Publications},
  pubmed       = {pmid:34032570},
  reportid     = {RWTH-2021-09113},
  url          = {https://publications.rwth-aachen.de/record/828379},
  volume       = {10},
}

@article{Hitch:819354,
  author       = {Hitch, Thomas C. A. and Riedel, Thomas and Oren, Aharon and Overmann, Jörg and Lawley, Trevor D. and Clavel, Thomas},
  title        = {Automated analysis of genomic sequences facilitates high-throughput and comprehensive description of bacteria},
  journaltitle = {ISME communications},
  year         = {2021},
  doi          = {10.1038/s43705-021-00017-z},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {16},
  publisher    = {Springer Nature},
  reportid     = {RWTH-2021-04989},
  url          = {https://publications.rwth-aachen.de/record/819354},
  volume       = {1},
}

@article{Innes:837765,
  author       = {Innes, Hamish and Nischalke, Hans Dieter and Guha, Indra Neil and Weiss, Karl Heinz and Irving, Will and Gotthardt, Daniel and Barnes, Eleanor and Fischer, Janett and Ansari, M. Azim and Rosendahl, Jonas and Lin, Shang-Kuan and Marot, Astrid and Pedergnana, Vincent and Casper, Markus and Benselin, Jennifer and Lammert, Frank and McLauchlan, John and Lutz, Philip L. and Hamill, Victoria and Mueller, Sebastian and Morling, Joanne R. and Semmler, Georg and Eyer, Florian and von Felden, Johann and Link, Alexander and Vogel, Arndt and Marquardt, Jens U. and Sulk, Stefan and Trebicka, Jonel and Valenti, Luca and Datz, Christian and Reiberger, Thomas and Schafmayer, Clemens and Berg, Thomas and Deltenre, Pierre and Hampe, Jochen and Stickel, Felix and Buch, Stephan},
  title        = {The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis},
  journaltitle = {Hepatology communications},
  year         = {2021},
  doi          = {10.1002/hep4.1886},
  keywords     = {,CRC1382-Project A09},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  publisher    = {Wiley},
  pubmed       = {pmid:34958182},
  reportid     = {RWTH-2022-00059},
  url          = {https://publications.rwth-aachen.de/record/837765},
}

@article{Iwakiri:834276,
  author       = {Iwakiri, Yasuko and Trebicka, Jonel},
  title        = {Portal hypertension in cirrhosis},
  journaltitle = {JHEP reports},
  year         = {2021},
  doi          = {10.1016/j.jhepr.2021.100316},
  keywords     = {,CRC1382-Project A09},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {100316},
  publisher    = {Elsevier},
  reportid     = {RWTH-2021-09763},
  subtitle     = {Pathophysiological mechanisms and therapy},
  url          = {https://publications.rwth-aachen.de/record/834276},
  volume       = {3},
}

@article{Jrdens:851563,
  author       = {Jördens, Markus Sebastian and Heinrichs, Lisa and Loosen, Sven H. and Wittig, Linda and Keitel, Verena and Schöler, David and Schulze-Hagen, Maximilian and Loberg, Christina and Antoch, Gerald and Knoefel, Wolfram Trudo and Lüdde, Tom and Fluegen, Georg and Roderburg, Christoph},
  title        = {Sarcopenia Predicts Cancer Mortality in Male but Not in Female Patients Undergoing Surgery for Cholangiocellular Carcinoma},
  journaltitle = {Cancers},
  year         = {2021},
  doi          = {10.3390/cancers13215359},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {21},
  pages        = {5359},
  publisher    = {MDPI},
  pubmed       = {pmid:34771524},
  reportid     = {RWTH-CONV-248651},
  url          = {https://publications.rwth-aachen.de/record/851563},
  volume       = {13},
}

@article{Koelfat:846351,
  author       = {Koelfat, Kiran V. K. and van Mierlo, Kim M. C. and Lodewick, Toine M. and Bloemen, Johanne G. and van der Kroft, Gregory and Amygdalos, Iakovos and Neumann, Ulf P. and Dejong, Cornelis H. C. and Jansen, Peter L. M. and Olde Damink, Steven W. M. and Schaap, Frank G.},
  title        = {Bile Salt and {FGF}19 Signaling in the Early Phase of Human Liver Regeneration},
  journaltitle = {Hepatology communications},
  year         = {2021},
  doi          = {10.1002/hep4.1728},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A07,CRC1382-Project A07},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1400--1411},
  publisher    = {Wiley},
  pubmed       = {pmid:34430784},
  reportid     = {RWTH-CONV-247763},
  url          = {https://publications.rwth-aachen.de/record/846351},
  volume       = {5},
}

@article{Kumar:820092,
  author       = {Kumar, Neeraj and Hitch, Thomas C. A. and Haller, Dirk and Lagkouvardos, Ilias and Clavel, Thomas},
  title        = {MiMiC: a bioinformatic approach for generation of synthetic communities from metagenomes},
  journaltitle = {Microbial biotechnology},
  year         = {2021},
  doi          = {10.1111/1751-7915.13845},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {1757--1770},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:34081399},
  reportid     = {RWTH-2021-05409},
  url          = {https://publications.rwth-aachen.de/record/820092},
  volume       = {14},
}

@article{Kurt:828359,
  author          = {Kurt, Berkan and Bündgens, Lukas and Wirtz, Theresa and Loosen, Sven H. and Schulze-Hagen, Maximilian and Truhn, Daniel and Brozat, Jonathan F. and Abu Jhaisha, Samira and Hohlstein, Philipp and Koek, Ger and Weiskirchen, Ralf and Trautwein, Christian and Tacke, Frank and Hamesch, Karim and Koch, Alexander},
  title           = {Serum Perilipin 2 ({PLIN}2) Predicts Multiple Organ Dysfunction in Critically Ill Patients},
  journaltitle    = {Biomedicines},
  year            = {2021},
  doi             = {10.3390/biomedicines9091210},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {9},
  pages           = {1210},
  publisher       = {MDPI},
  reportid        = {RWTH-2021-09099},
  url             = {https://publications.rwth-aachen.de/record/828359},
  volume          = {9},
}

@article{Lambrecht:828495,
  author       = {Lambrecht, Joeri and Porsch-Özçürümez, Mustafa and Best, Jan and Jost-Brinkmann, Fabian and Roderburg, Christoph and Demir, Münevver and Tacke, Frank and Mohr, Raphael},
  title        = {The {APAC} Score},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2021},
  doi          = {10.3390/jcm10153392},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {15},
  pages        = {3392},
  publisher    = {MDPI},
  pubmed       = {pmid:34362181},
  reportid     = {RWTH-2021-09144},
  subtitle     = {A Novel and Highly Performant Serological Tool for Early Diagnosis of Hepatocellular Carcinoma in Patients with Liver Cirrhosis},
  url          = {https://publications.rwth-aachen.de/record/828495},
  volume       = {10},
}

@article{Lambrecht:815757,
  author       = {Lambrecht, Joeri and Tacke, Frank},
  title        = {Controversies and Opportunities in the Use of Inflammatory Markers for Diagnosis or Risk Prediction in Fatty Liver Disease},
  journaltitle = {Frontiers in immunology},
  year         = {2021},
  doi          = {10.3389/fimmu.2020.634409},
  keywords     = {,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {634409},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2021-02821},
  url          = {https://publications.rwth-aachen.de/record/815757},
  volume       = {11},
}

@article{Loosen:851171,
  author       = {Loosen, Sven H and Gorgulho, Joao and Jördens, Markus S. and Schulze-Hagen, Maximilian and Beier, Fabian and Vucur, Mihael and Schneider, Anne Theres and Koppe, Christiane and Mertens, Alexander and Kather, Jakob N. and Tacke, Frank and Keitel, Verena and Brümmendorf, Tim Henrik and Roderburg, Christoph and Lüdde, Tom},
  title        = {Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy},
  journaltitle = {Frontiers in oncology},
  year         = {2021},
  doi          = {10.3389/fonc.2021.646883},
  keywords     = {,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {646883},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:33869041},
  reportid     = {RWTH-CONV-248259},
  url          = {https://publications.rwth-aachen.de/record/851171},
  volume       = {11},
}

@article{Loosen:846383,
  author       = {Loosen, Sven H. and Bock, Hans H. and Hellmich, Martin and Knoefel, Wolfram T. and Trautwein, Christian and Keitel, Verena and Bode, Johannes G. and Neumann, Ulf P. and Lüdde, Tom},
  title        = {Hospital Mortality and Current Trends in Liver Transplantation in Germany},
  journaltitle = {Deutsches Ärzteblatt international},
  year         = {2021},
  doi          = {10.3238/arztebl.m2021.0210},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Köln},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {29/30},
  pages        = {497--502},
  publisher    = {Dt. Ärzte-Verl.},
  pubmed       = {pmid:33888199},
  reportid     = {RWTH-CONV-247795},
  subtitle     = {A Systematic Analysis of Standardized Hospital Discharge Data, 2008–2017},
  url          = {https://publications.rwth-aachen.de/record/846383},
  volume       = {118},
}

@article{Loosen:846376,
  author       = {Loosen, Sven H. and van den Bosch, Vincent and Gorgulho, Joao and Schulze-Hagen, Maximilian and Kandler, Jennis and Jördens, Markus S. and Tacke, Frank and Loberg, Christina and Antoch, Gerald and Brümmendorf, Tim Henrik and Neumann, Ulf P. and Kuhl, Christiane K. and Lüdde, Tom and Roderburg, Christoph},
  title        = {Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2021},
  doi          = {10.3390/jcm10071361},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A04,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {1361},
  publisher    = {MDPI},
  pubmed       = {pmid:33806224},
  reportid     = {RWTH-CONV-247788},
  url          = {https://publications.rwth-aachen.de/record/846376},
  volume       = {10},
}

@article{Loosen:860351,
  author       = {Loosen, Sven H. and Paffenholz, Pia and Lüdde, Tom and Kostev, Karel and Roderburg, Christoph},
  title        = {Diverticular disease is associated with an increased incidence rate of depression and anxiety disorders},
  journaltitle = {International journal of colorectal disease},
  year         = {2021},
  doi          = {10.1007/s00384-021-03937-3},
  keywords     = {,CRC1382-Project A01},
  location     = {Berlin},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {2437--2443},
  publisher    = {Springer},
  pubmed       = {pmid:33937941},
  reportid     = {RWTH-2022-11345},
  url          = {https://publications.rwth-aachen.de/record/860351},
  volume       = {36},
}

@article{Loosen:846312,
  author          = {Loosen, Sven H. and Roderburg, Christoph and Alizai, Patrick H. and Roeth, Anjali A. and Schmitz, Sophia M. and Vucur, Mihael and Luedde, Mark and Schöler, David and Paffenholz, Pia and Tacke, Frank and Trautwein, Christian and Lüdde, Tom and Neumann, Ulf P. and Ulmer, Tom F.},
  title           = {Comparative Analysis of Circulating Biomarkers for Patients Undergoing Resection of Colorectal Liver Metastases},
  journaltitle    = {Diagnostics},
  year            = {2021},
  doi             = {10.3390/diagnostics11111999},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {11},
  pages           = {1999},
  publisher       = {MDPI},
  pubmed          = {pmid:34829346},
  reportid        = {RWTH-CONV-247724},
  url             = {https://publications.rwth-aachen.de/record/846312},
  volume          = {11},
}

@article{Luciani:828414,
  author       = {Luciani, Cécilia and Hager, Fabian Tobias and Cerovic, Vuk and Lelouard, Hugues},
  title        = {Dendritic cell functions in the inductive and effector sites of intestinal immunity},
  journaltitle = {Mucosal immunology},
  year         = {2021},
  doi          = {10.1038/s41385-021-00448-w},
  keywords     = {,CRC1382-Project B03},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {40--50},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2021-09127},
  url          = {https://publications.rwth-aachen.de/record/828414},
  volume       = {15},
}

@article{Misselwitz:807345,
  author          = {Misselwitz, Benjamin and Wyss, Annika and Raselli, Tina and Cerovic, Vuk and Sailer, Andreas W. and Krupka, Niklas and Ruiz, Florian and Pot, Caroline and Pabst, Oliver},
  title           = {The oxysterol receptor {GPR}183 in inflammatory bowel diseases},
  journaltitle    = {British journal of pharmacology},
  year            = {2021},
  doi             = {10.1111/bph.15311},
  journalsubtitle = {BJP online},
  keywords        = {,CRC1382-Project B03,CRC1382-Project B06,CRC1382-Project Q04},
  location        = {Malden, MA},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {16},
  pages           = {3140--3156},
  publisher       = {Wiley},
  pubmed          = {pmid:33145756},
  reportid        = {RWTH-2020-11291},
  url             = {https://publications.rwth-aachen.de/record/807345},
  volume          = {178},
}

@article{Monteiro:815754,
  author       = {Monteiro, Sofia and Grandt, Josephine and Uschner, Frank Erhard and Kimer, Nina and Madsen, Jan Lysgård and Schierwagen, Robert and Klein, Sabine and Welsch, Christoph and Schäfer, Liliana and Jansen, Christian and Claria, Joan and Alcaraz-Quiles, José and Arroyo, Vicente and Moreau, Richard and Fernandez, Javier and Bendtsen, Flemming and Mehta, Gautam and Gluud, Lise Lotte and Møller, Søren and Praktiknjo, Michael and Trebicka, Jonel},
  title        = {Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation},
  journaltitle = {Gut},
  year         = {2021},
  doi          = {10.1136/gutjnl-2019-320170},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {379--387},
  publisher    = {BMJ Publishing Group},
  reportid     = {RWTH-2021-02818},
  url          = {https://publications.rwth-aachen.de/record/815754},
  volume       = {70},
}

@article{Mller:846176,
  author       = {Müller, Katrin and Honcharova-Biletska, Hanna and Koppe, Christiane and Egger, Michèle and Chan, Lap Kwan and Schneider, Anne T. and Küsgens, Lena and Böhm, Friederike and Boege, Yannick and Healy, Marc E. and Schmitt, Johannes and Comtesse, Sarah and Castoldi, Mirco and Preisinger, Christian and Szydlowska, Marta and Focaccia, Enrico and Gaisa, Nadine and Loosen, Sven H. and Jörs, Simone and Tacke, Frank and Roderburg, Christoph and Keitel, Verena and Bode, Johannes G. and Boor, Peter and Davis, Roger J. and Longerich, Thomas and Geisler, Fabian and Heikenwalder, Mathias and Weber, Achim and Vucur, Mihael and Lüdde, Tom},
  title        = {{JNK} signaling prevents biliary cyst formation through a {CASPASE}-8-dependent function of {RIPK}1 during aging},
  journaltitle = {Proceedings of the National Academy of Sciences of the United States of America},
  year         = {2021},
  doi          = {10.1073/pnas.2007194118},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {e2007194118},
  publisher    = {National Acad. of Sciences},
  pubmed       = {pmid:33798093},
  reportid     = {RWTH-CONV-247589},
  url          = {https://publications.rwth-aachen.de/record/846176},
  volume       = {118},
}

@article{Muschaweck:834552,
  author       = {Muschaweck, Moritz and Kopplin, Lydia and Ticconi, Fabio and Schippers, Angela and Iljazovic, Aida and Gálvez, Eric J. C. and Abdallah, Ali T. and Wagner, Norbert and Costa, Ivan G. and Strowig, Till and Pabst, Oliver},
  title        = {Cognate recognition of microbial antigens defines constricted {CD}4$^{+}$ T cell receptor repertoires in the inflamed colon},
  journaltitle = {Immunity},
  year         = {2021},
  doi          = {10.1016/j.immuni.2021.08.014},
  keywords     = {,CRC1382-Project B06,CRC1382-Project Q04,CRC1382-Project B02,CRC1382-Project B02},
  location     = {[Cambridge, Mass.]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {2565--2577.e6},
  publisher    = {Cell Press},
  pubmed       = {pmid:34582747},
  reportid     = {RWTH-2021-09985},
  url          = {https://publications.rwth-aachen.de/record/834552},
  volume       = {54},
}

@article{Muti:845917,
  author       = {Muti, Hannah Sophie and Heij, Lara Rosaline and Keller, Gisela and Kohlruss, Meike and Langer, Rupert and Dislich, Bastian and Cheong, Jae-Ho and Kim, Young-Woo and Kim, Hyunki and Kook, Myeong-Cherl and Cunningham, David and Allum, William H. and Langley, Ruth E. and Nankivell, Matthew G. and Quirke, Philip and Hayden, Jeremy D. and West, Nicholas P. and Irvine, Andrew J. and Yoshikawa, Takaki and Oshima, Takashi and Huss, Ralf and Grosser, Bianca and Roviello, Franco and d'Ignazio, Alessia and Quaas, Alexander and Alakus, Hakan and Tan, Xiuxiang and Pearson, Alexander T. and Lüdde, Tom and Ebert, Matthias P. and Jäger, Dirk and Trautwein, Christian and Gaisa, Nadine Therese and Grabsch, Heike I. and Kather, Jakob Nikolas},
  title        = {Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer},
  journaltitle = {The lancet / Digital health},
  year         = {2021},
  doi          = {10.1016/S2589-7500(21)00133-3},
  keywords     = {,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {e654--e664},
  publisher    = {The Lancet},
  pubmed       = {pmid:34417147},
  reportid     = {RWTH-CONV-247332},
  subtitle     = {A retrospective multicentre cohort study},
  url          = {https://publications.rwth-aachen.de/record/845917},
  volume       = {3},
}

@article{Peiseler:828489,
  author          = {Peiseler, Moritz and Tacke, Frank},
  title           = {An Unexpected Line of Defense},
  journaltitle    = {Hepatology},
  year            = {2021},
  doi             = {10.1002/hep.31895},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05},
  location        = {New York and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {5},
  pages           = {2888--2890},
  publisher       = {Wiley Interscience},
  pubmed          = {pmid:33977566},
  reportid        = {RWTH-2021-09140},
  subtitle        = {Hepatoprotective Eosinophils in Ischemia‐Reperfusion Injury},
  url             = {https://publications.rwth-aachen.de/record/828489},
  volume          = {74},
}

@article{Peiseler:815753,
  author       = {Peiseler, Moritz and Tacke, Frank},
  title        = {Inflammatory Mechanisms Underlying Nonalcoholic Steatohepatitis and the Transition to Hepatocellular Carcinoma},
  journaltitle = {Cancers},
  year         = {2021},
  doi          = {10.3390/cancers13040730},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {730},
  publisher    = {MDPI},
  reportid     = {RWTH-2021-02817},
  url          = {https://publications.rwth-aachen.de/record/815753},
  volume       = {13},
}

@article{Prax:846068,
  author       = {Prax, Nicoletta and Wagner, Stefanie and Schardt, Jakob and Neuhaus, Klaus and Clavel, Thomas and Fuchs, Thilo M.},
  title        = {A diet-specific microbiota drives Salmonella Typhimurium to adapt its in vivo response to plant-derived substrates},
  journaltitle = {Animal microbiome},
  year         = {2021},
  doi          = {10.1186/s42523-021-00082-8},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {24},
  publisher    = {BioMed Central},
  pubmed       = {pmid:33731218},
  reportid     = {RWTH-CONV-247481},
  url          = {https://publications.rwth-aachen.de/record/846068},
  volume       = {3},
}

@article{Queck:828617,
  author       = {Queck, Alexander and Uschner, Frank E. and Ferstl, Philip G. and Schulz, Martin and Brol, Maximilian J. and Praktiknjo, Michael and Schierwagen, Robert and Klein, Sabine and Strassburg, Christian P. and Meyer, Carsten and Jansen, Christian and Berres, Marie-Luise and Trebicka, Jonel},
  title        = {Role of circulating angiogenin levels in portal hypertension and {TIPS}},
  journaltitle = {PLOS ONE},
  year         = {2021},
  doi          = {10.1371/journal.pone.0256473},
  keywords     = {,CRC1382-Project B04,CRC1382-Project A09,CRC1382-Project A09},
  location     = {San Francisco, California, US},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {e0256473},
  publisher    = {PLOS},
  reportid     = {RWTH-2021-09236},
  url          = {https://publications.rwth-aachen.de/record/828617},
  volume       = {16},
}

@article{Reitmeier:835050,
  author       = {Reitmeier, Sandra and Hitch, Thomas C. A. and Treichel, Nicole and Fikas, Nikolaos and Hausmann, Bela and Ramer-Tait, Amanda E. and Neuhaus, Klaus and Berry, David and Haller, Dirk and Lagkouvardos, Ilias and Clavel, Thomas},
  title        = {Handling of spurious sequences affects the outcome of high-throughput 16S r{RNA} gene amplicon profiling},
  journaltitle = {ISME communications},
  year         = {2021},
  doi          = {10.1038/s43705-021-00033-z},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project Q02},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {31},
  publisher    = {Springer Nature},
  reportid     = {RWTH-2021-10255},
  url          = {https://publications.rwth-aachen.de/record/835050},
  volume       = {1},
}

@article{Roderburg:846384,
  author       = {Roderburg, Christoph and Loosen, Sven H. and Bednarsch, Jan and Alizai, Patrick H. and Roeth, Anjali A. and Schmitz, Sophia M. and Vucur, Mihael and Luedde, Mark and Paffenholz, Pia and Tacke, Frank and Trautwein, Christian and Ulmer, Tom F. and Neumann, Ulf Peter and Lüdde, Tom},
  title        = {Levels of Circulating {PD}-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma},
  journaltitle = {International journal of molecular sciences},
  year         = {2021},
  doi          = {10.3390/ijms22126569},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {6569},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:34207359},
  reportid     = {RWTH-CONV-247796},
  url          = {https://publications.rwth-aachen.de/record/846384},
  volume       = {22},
}

@article{Roderburg:860336,
  author       = {Roderburg, Christoph and Loosen, Sven H. and Kunstein, Anselm and Mohr, Raphael and Jördens, Markus S. and Luedde, Mark and Kostev, Karel and Lüdde, Tom},
  title        = {Cancer Patients Have an Increased Incidence of Dementia: A Retrospective Cohort Study of 185,736 Outpatients in Germany},
  journaltitle = {Cancers},
  year         = {2021},
  doi          = {10.3390/cancers13092027},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {2027},
  publisher    = {MDPI},
  pubmed       = {pmid:33922235},
  reportid     = {RWTH-2022-11331},
  url          = {https://publications.rwth-aachen.de/record/860336},
  volume       = {13},
}

@article{Rolles:851153,
  author       = {Rolles, Benjamin and Gorgulho, Joao and Tometten, Mareike and Roderburg, Christoph and Vieri, Margherita and Abels, Anne and Vucur, Mihael and Heymann, Felix and Tacke, Frank and Brümmendorf, Tim Henrik and Lüdde, Tom and Beier, Fabian and Loosen, Sven H.},
  title        = {Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy},
  journaltitle = {Frontiers in oncology},
  year         = {2021},
  doi          = {10.3389/fonc.2021.729207},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {729207},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:34490122},
  reportid     = {RWTH-CONV-248241},
  url          = {https://publications.rwth-aachen.de/record/851153},
  volume       = {11},
}

@article{Roohani:828494,
  author       = {Roohani, Siyer and Tacke, Frank},
  title        = {Liver Injury and the Macrophage Issue},
  journaltitle = {International journal of molecular sciences},
  year         = {2021},
  doi          = {10.3390/ijms22147249},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {14},
  pages        = {7249},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:34298870},
  reportid     = {RWTH-2021-09143},
  subtitle     = {Molecular and Mechanistic Facts and Their Clinical Relevance},
  url          = {https://publications.rwth-aachen.de/record/828494},
  volume       = {22},
}

@article{Schippers:808794,
  author       = {Schippers, Angela and Hübel, Jessica and Heymann, Felix and Clahsen, Thomas and Eswaran, Sreepradha and Schlepütz, Sarah and Püllen, Robin and Gaßler, Nikolaus and Tenbrock, Klaus and Tacke, Frank and Wagner, Norbert},
  title        = {{MA}d{CAM}-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2021},
  doi          = {10.1016/j.jcmgh.2020.12.003},
  keywords     = {,CRC1382-Project B02,CRC1382-Project B02,CRC1382-Project B05,CRC1382-Project B02},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {1227--1250.el},
  publisher    = {Elsevier},
  pubmed       = {pmid:33316453},
  reportid     = {RWTH-2020-12305},
  shortjournal = {CMGH},
  url          = {https://publications.rwth-aachen.de/record/808794},
  volume       = {11},
}

@article{Schneider:848652,
  author       = {Schneider, Carolin Victoria and Fromme, Malin and Schneider, Kai Markus and Bruns, Tony and Strnad, Pavel},
  title        = {Mortality in Patients With Genetic and Environmental Risk of Liver Disease},
  journaltitle = {The American journal of gastroenterology},
  year         = {2021},
  doi          = {10.14309/ajg.0000000000001326},
  keywords     = {,CRC1382-Project B07,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03},
  location     = {Alphen aan den Rijn, The Netherlands},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1741--1745},
  publisher    = {Wolters Kluwer Health, Inc.},
  pubmed       = {pmid:34131090},
  reportid     = {RWTH-2022-06191},
  url          = {https://publications.rwth-aachen.de/record/848652},
  volume       = {116},
}

@article{Schneider:808392,
  author       = {Schneider, Carolin Victoria and Kleinjans, Moritz and Fromme, Malin and Schneider, Kai Markus and Strnad, Pavel},
  title        = {Phenome-wide association study in adult coeliac disease},
  journaltitle = {Alimentary pharmacology \& therapeutics},
  year         = {2021},
  doi          = {10.1111/apt.16206},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {510--518},
  publisher    = {Blackwell Science},
  pubmed       = {pmid:33280147},
  reportid     = {RWTH-2020-12030},
  subtitle     = {Role of {HLA} subtype},
  url          = {https://publications.rwth-aachen.de/record/808392},
  volume       = {53},
}

@article{Schneider:815759,
  author       = {Schneider, Kai Markus and Elfers, Carsten and Ghallab, Ahmed and Schneider, Carolin Victoria and Galvez, Eric J. C. and Mohs, Antje and Gui, Wenfang and Candels, Lena Susanna and Wirtz, Theresa and Zuehlke, Sebastian and Spiteller, Michael and Myllys, Maiju and Roulet, Alain and Ouzerdine, Amirouche and Lelouvier, Benjamin and Kilic, Konrad and Liao, Lijun and Nier, Anika and Latz, Eicke and Bergheim, Ina and Thaiss, Christoph A. and Hengstler, Jan G. and Strowig, Till and Trautwein, Christian},
  title        = {Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2021},
  doi          = {10.1016/j.jcmgh.2020.11.002},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A06,CRC1382-Project A08},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {909--933},
  publisher    = {Elsevier},
  pubmed       = {pmid:33189892},
  reportid     = {RWTH-2021-02823},
  shortjournal = {CMGH},
  url          = {https://publications.rwth-aachen.de/record/815759},
  volume       = {11},
}

@article{Schubert:848653,
  author       = {Schubert, Kristin and Karkossa, Isabel and Schor, Jana and Engelmann, Beatrice and Steinheuer, Lisa Maria and Bruns, Tony and Rolle-Kampczyk, Ulrike and Hackermüller, Jörg and von Bergen, Martin},
  title        = {A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation},
  journaltitle = {Frontiers in immunology},
  year         = {2021},
  doi          = {10.3389/fimmu.2021.616967},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {616967},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:34108957},
  reportid     = {RWTH-2022-06192},
  url          = {https://publications.rwth-aachen.de/record/848653},
  volume       = {12},
}

@article{SchulzeHagen:851422,
  author       = {Schulze-Hagen, Maximilian and Roderburg, Christoph and Wirtz, Theresa H. and Jördens, Markus S. and Bündgens, Lukas and Abu Jhaisha, Samira and Hohlstein, Philipp and Brozat, Jonathan Frederik and Bruners, Philipp and Loberg, Christina and Kuhl, Christiane K. and Trautwein, Christian and Tacke, Frank and Lüdde, Tom and Loosen, Sven H. and Koch, Alexander},
  title        = {Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2021},
  doi          = {10.3390/jcm10163741},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A01,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {16},
  pages        = {3741},
  publisher    = {MDPI},
  pubmed       = {pmid:34442036},
  reportid     = {RWTH-CONV-248510},
  url          = {https://publications.rwth-aachen.de/record/851422},
  volume       = {10},
}

@article{Seikrit:824679,
  author       = {Seikrit, Claudia and Pabst, Oliver},
  title        = {The immune landscape of IgA induction in the gut},
  journaltitle = {Seminars in immunopathology},
  year         = {2021},
  doi          = {10.1007/s00281-021-00879-4},
  keywords     = {,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {Berlin; Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {627--637},
  publisher    = {Springer},
  pubmed       = {pmid:34379174},
  reportid     = {RWTH-2021-07745},
  url          = {https://publications.rwth-aachen.de/record/824679},
  volume       = {43},
}

@article{Streidl:809963,
  author       = {Streidl, Theresa and Karkossa, Isabel and Segura Muñoz, Rafael R. and Eberl, Claudia and Zaufel, Alex and Plagge, Johannes and Schmaltz, Robert and Schubert, Kristin and Basic, Marijana and Schneider, Kai Markus and Afify, Mamdouh and Trautwein, Christian and Tolba, René H. and Stecher, Bärbel and Doden, Heidi L. and Ridlon, Jason M. and Ecker, Josef and Moustafa, Tarek and von Bergen, Martin and Ramer-Tait, Amanda E. and Clavel, Thomas},
  title        = {The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice},
  journaltitle = {Gut microbes},
  year         = {2021},
  doi          = {10.1080/19490976.2020.1854008},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A05},
  location     = {Austin, Tex.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1--21},
  publisher    = {Landes Bioscience},
  pubmed       = {pmid:33382950},
  reportid     = {RWTH-2021-00279},
  url          = {https://publications.rwth-aachen.de/record/809963},
  volume       = {13},
}

@article{Tacke:828492,
  author       = {Tacke, Frank and Weiskirchen, Ralf},
  title        = {Non-alcoholic fatty liver disease ({NAFLD})/non-alcoholic steatohepatitis ({NASH})-related liver fibrosis},
  journaltitle = {Annals of translational medicine},
  year         = {2021},
  doi          = {10.21037/atm-20-4354},
  keywords     = {,CRC1382-Project B05},
  location     = {Shatin, NT},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {729},
  publisher    = {AME Publishing Company},
  pubmed       = {pmid:33987427},
  reportid     = {RWTH-2021-09141},
  shortjournal = {ATM},
  subtitle     = {Mechanisms, treatment and prevention},
  url          = {https://publications.rwth-aachen.de/record/828492},
  volume       = {9},
}

@article{Torres:834274,
  author       = {Torres, Sandra and Brol, Maximilian J. and Magdaleno, Fernando and Schierwagen, Robert and Uschner, Frank E. and Klein, Sabine and Ortiz, Cristina and Tyc, Olaf and Bachtler, Nadine and Stunden, James and Bertheloot, Damien and Kitanovic, Ana and Sanchez, Brian and Schrum, Jacob and Roush, William R. and Franchi, Luigi and Byth, Kate and Latz, Eicke and Trebicka, Jonel},
  title        = {The Specific {NLRP}3 Antagonist {IFM}-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis},
  journaltitle = {Frontiers in molecular biosciences},
  year         = {2021},
  doi          = {10.3389/fmolb.2021.715765},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09,CRC1382-Project A09},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {715765},
  publisher    = {Frontiers},
  reportid     = {RWTH-2021-09761},
  url          = {https://publications.rwth-aachen.de/record/834274},
  volume       = {8},
}

@article{Trebicka:834279,
  author       = {Trebicka, Jonel and Bork, Peer and Krag, Aleksander and Arumugam, Manimozhiyan},
  title        = {Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure},
  journaltitle = {Nature reviews / Gastroenterology \& hepatology},
  year         = {2021},
  doi          = {10.1038/s41575-020-00376-3},
  keywords     = {,CRC1382-Project A09},
  location     = {Basingstoke},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {167--180},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2021-09766},
  url          = {https://publications.rwth-aachen.de/record/834279},
  volume       = {18},
}

@article{Trebicka:834278,
  author       = {Trebicka, Jonel and Macnaughtan, Jane and Schnabl, Bernd and Shawcross, Debbie L. and Bajaj, Jasmohan S.},
  title        = {The microbiota in cirrhosis and its role in hepatic decompensation},
  journaltitle = {Journal of hepatology},
  year         = {2021},
  doi          = {10.1016/j.jhep.2020.11.013},
  keywords     = {,CRC1382-Project A09},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {Supplement 1},
  pages        = {S67--S81},
  publisher    = {Elsevier Science},
  reportid     = {RWTH-2021-09765},
  url          = {https://publications.rwth-aachen.de/record/834278},
  volume       = {75},
}

@article{Voss:834553,
  author       = {Voss, Jessica and Schneider, Carolin Victoria and Kleinjans, Moritz and Bruns, Tony and Trautwein, Christian and Strnad, Pavel},
  title        = {Hepatobiliary phenotype of individuals with chronic intestinal disorders},
  journaltitle = {Scientific reports},
  year         = {2021},
  doi          = {10.1038/s41598-021-98843-7},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {19954},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  reportid     = {RWTH-2021-09986},
  url          = {https://publications.rwth-aachen.de/record/834553},
  volume       = {11},
}

@article{Wagner:828378,
  author       = {Wagner, Camille and Torow, Natalia and Hornef, Mathias W. and Lelouard, Hugues},
  title        = {Spatial and temporal key steps in early-life intestinal immune system development and education},
  journaltitle = {The FEBS journal},
  year         = {2021},
  doi          = {10.1111/febs.16047},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {Oxford and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {16},
  pages        = {4731--4757},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:34076962},
  reportid     = {RWTH-2021-09112},
  url          = {https://publications.rwth-aachen.de/record/828378},
  volume       = {289},
}

@article{Wen:815760,
  author       = {Wen, Yankai and Lambrecht, Joeri and Ju, Cynthia and Tacke, Frank},
  title        = {Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities},
  journaltitle = {Cellular \& molecular immunology},
  year         = {2021},
  doi          = {10.1038/s41423-020-00558-8},
  keywords     = {,CRC1382-Project B05},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {45--56},
  publisher    = {Nature Publ. Group},
  reportid     = {RWTH-2021-02824},
  url          = {https://publications.rwth-aachen.de/record/815760},
  volume       = {18},
}

@article{Wirtz:811445,
  author       = {Wirtz, Theresa and Reuken, Philipp A. and Jansen, Christian and Fischer, Petra and Bergmann, Irina and Backhaus, Christina and Emontzpohl, Christoph and Reißing, Johanna and Brandt, Elisa Fabiana and Koenen, M. Teresa and Schneider, Kai Markus and Schierwagen, Robert and Brol, Maximilian J. and Chang, Johannes and Zimmermann, Henning W. and Köse-Vogel, Nilay and Eggermann, Thomas and Kurth, Ingo and Stoppe, Christian and Bucala, Richard and Bernhagen, Jürgen and Praktiknjo, Michael and Stallmach, Andreas and Trautwein, Christian and Trebicka, Jonel and Bruns, Tony and Berres, Marie-Luise},
  title        = {Balance between macrophage migration inhibitory factor and s{CD}74 predicts outcome in patients with acute decompensation of cirrhosis},
  journaltitle = {JHEP reports},
  year         = {2021},
  doi          = {10.1016/j.jhepr.2020.100221},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B04,CRC1382-Project B07,CRC1382-Project B09,CRC1382-Project A09,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A09},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {100221},
  publisher    = {Elsevier},
  pubmed       = {pmid:33659891},
  reportid     = {RWTH-2021-01189},
  url          = {https://publications.rwth-aachen.de/record/811445},
  volume       = {3},
}

@article{Wirtz:828618,
  author       = {Wirtz, Theresa and Saal, Alena and Bergmann, Irina and Fischer, Petra and Heinrichs, Daniel and Brandt, Elisa Fabiana and Koenen, Maria Teresa and Djudjaj, Sonja and Schneider, Kai Markus and Boor, Peter and Bucala, Richard and Weiskirchen, Ralf and Bernhagen, Jürgen and Trautwein, Christian and Berres, Marie-Luise},
  title        = {Macrophage migration inhibitory factor exerts pro‐proliferative and anti‐apoptotic effects via {CD}74 in murine hepatocellular carcinoma},
  journaltitle = {British journal of pharmacology},
  year         = {2021},
  doi          = {10.1111/bph.15622},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B04,CRC1382-Project B09,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Malden, MA},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {22},
  pages        = {4452--4467},
  publisher    = {Wiley},
  pubmed       = {pmid:34250589},
  reportid     = {RWTH-2021-09237},
  url          = {https://publications.rwth-aachen.de/record/828618},
  volume       = {178},
}

@article{Zuo:834142,
  author       = {Zuo, Simin and Al Rawashdeh, Wa’el and Rosenhain, Stefanie and Magnuska, Zuzanna and Gyamfuah, Yamoah Grace and Kießling, Fabian and Gremse, Felix},
  title        = {Mixing Matrix-corrected Whole-body Pharmacokinetic Modeling Using Longitudinal Micro-computed Tomography and Fluorescence-mediated Tomography},
  journaltitle = {Molecular imaging \& biology},
  year         = {2021},
  doi          = {10.1007/s11307-021-01623-y},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {Cham},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {963--974},
  publisher    = {Springer Nature Switzerland},
  pubmed       = {pmid:34231106},
  reportid     = {RWTH-2021-09681},
  url          = {https://publications.rwth-aachen.de/record/834142},
  volume       = {23},
}

@article{Afrizal:854345,
  author       = {Afrizal, Afrizal and Jennings, Susan A. V. and Hitch, Thomas C. A. and Riedel, Thomas and Basic, Marijana and Panyot, Atscharah and Treichel, Nicole and Hager, Fabian Tobias and Wong, Erin Oi-Yan and Wolter, Birger and Viehof, Alina and von Strempel, Alexandra and Eberl, Claudia and Buhl, Eva Miriam and Abt, Birte and Bleich, André and Tolba, René H. and Blank, Lars Mathias and Navarre, William W. and Kießling, Fabian and Horz, Hans-Peter and Torow, Natalia and Cerovic, Vuk and Stecher, Bärbel and Strowig, Till and Overmann, Jörg and Clavel, Thomas},
  title        = {Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities},
  journaltitle = {Cell host and microbe},
  year         = {2022},
  doi          = {10.1016/j.chom.2022.09.011},
  keywords     = {,CRC1382-Project A06,CRC1382-Project B03,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project Q01,CRC1382-Project Q02,CRC1382-Project A05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {1630--1645.e25},
  publisher    = {Elsevier},
  reportid     = {RWTH-2022-09486},
  url          = {https://publications.rwth-aachen.de/record/854345},
  volume       = {30},
}

@article{Atkinson:842994,
  author       = {Atkinson, Stephen Rahul and Aly, Mahmoud and Remih, Katharina and Tyson, Luke David and Guldiken, Nurdan and Goldin, Robert and Quaglia, Alberto and Thursz, Mark and Strnad, Pavel},
  title        = {Serum keratin 19 ({CYFRA}21-1) is a prognostic biomarker in severe alcoholic hepatitis},
  journaltitle = {Liver international},
  year         = {2022},
  doi          = {10.1111/liv.15218},
  keywords     = {,CRC1382-Project A03,CRC1382-Project A03},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {1049--1057},
  publisher    = {Wiley-Blackwell},
  reportid     = {RWTH-2022-02813},
  url          = {https://publications.rwth-aachen.de/record/842994},
  volume       = {42},
}

@article{Ay:842081,
  author          = {Ay, Ümran and Lenicek, Martin and Classen, Arno and Olde Damink, Steven W. M. and Bolm, Carsten and Schaap, Frank G.},
  title           = {New Kids on the Block},
  journaltitle    = {Metabolites},
  year            = {2022},
  doi             = {10.3390/metabo12020176},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A07,CRC1382-Project A07,CRC1382-Project A07},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {176},
  publisher       = {MDPI},
  reportid        = {RWTH-2022-02206},
  subtitle        = {Bile Salt Conjugates of Microbial Origin},
  url             = {https://publications.rwth-aachen.de/record/842081},
  volume          = {12},
}

@article{Bednarsch:847208,
  author       = {Bednarsch, Jan and Czigany, Zoltan and Heij, Lara R. and Amygdalos, Iakovos and Heise, Daniel and Bruners, Philip and Ulmer, Tom F. and Neumann, Ulf Peter and Lang, Sven A.},
  title        = {The role of re-resection in recurrent hepatocellular carcinoma},
  journaltitle = {Langenbeck's archives of surgery},
  year         = {2022},
  doi          = {10.1007/s00423-022-02545-1},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {2381--2391},
  publisher    = {Springer},
  reportid     = {RWTH-2022-05151},
  url          = {https://publications.rwth-aachen.de/record/847208},
  volume       = {407},
}

@article{Bellais:841321,
  author       = {Bellais, Samuel and Nehlich, Mélanie and Ania, Maryne and Duquenoy, Aurore and Mazier, Wilfrid and van den Engh, Ger and Baijer, Jan and Treichel, Nicole and Clavel, Thomas and Belotserkovsky, Ilia and Thomas, Vincent},
  title        = {Species-targeted sorting and cultivation of commensal bacteria from the gut microbiome using flow cytometry under anaerobic conditions},
  journaltitle = {Microbiome},
  year         = {2022},
  doi          = {10.1186/s40168-021-01206-7},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project Q02},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {24},
  publisher    = {Biomed Central},
  pubmed       = {pmid:35115054},
  reportid     = {RWTH-2022-01629},
  url          = {https://publications.rwth-aachen.de/record/841321},
  volume       = {10},
}

@article{Bhargava:855075,
  author       = {Bhargava, Shruti and Merckelbach, Erik and Noels, Heidi and Vohra, Ashima and Jankowski, Joachim},
  title        = {Homeostasis in the Gut Microbiota in Chronic Kidney Disease},
  journaltitle = {Toxins},
  year         = {2022},
  doi          = {10.3390/toxins14100648},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {648},
  publisher    = {MDPI},
  reportid     = {RWTH-2022-09971},
  url          = {https://publications.rwth-aachen.de/record/855075},
  volume       = {14},
}

@article{Biancacci:839980,
  author       = {Biancacci, Ilaria and De Lorenzi, Federica and Theek, Benjamin and Bai, Xiangyang and May, Jan-Niklas and Consolino, Lorena and Baues, Maike and Moeckel, Diana and Gremse, Felix and Stillfried, Saskia and El Shafei, Asmaa and Benderski, Karina and Azadkhah Shalmani, Armin and Wang, Alec and Momoh, Jeffrey and Peña, Quim and Buhl, Eva Miriam and Buyel, Johannes Felix and Hennink, Wim and Kießling, Fabian and Metselaar, Josbert and Shi, Yang and Lammers, Twan},
  title        = {Monitoring {EPR} Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles},
  journaltitle = {Advanced science},
  year         = {2022},
  doi          = {10.1002/advs.202103745},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {Weinheim},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {2103745},
  publisher    = {Wiley-VCH},
  reportid     = {RWTH-2022-00963},
  url          = {https://publications.rwth-aachen.de/record/839980},
}

@article{Brandt:861915,
  author       = {Brandt, Elisa F. and Baues, Maike and Wirtz, Theresa H. and May, Jan-Niklas and Fischer, Petra and Beckers, Anika and Schüre, Björn-Carsten and Sahin, Hacer and Trautwein, Christian and Lammers, Twan and Berres, Marie-Luise},
  title        = {Chemokine {CXCL}10 Modulates the Tumor Microenvironment of Fibrosis-Associated Hepatocellular Carcinoma},
  journaltitle = {International journal of molecular sciences},
  year         = {2022},
  doi          = {10.3390/ijms23158112},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B04,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {15},
  pages        = {8112},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:35897689},
  reportid     = {RWTH-CONV-249887},
  url          = {https://publications.rwth-aachen.de/record/861915},
  volume       = {23},
}

@article{Brozat:844848,
  author       = {Brozat, Jonathan F. and Brandt, Elisa Fabiana and Stark, Myriam and Fischer, Petra and Wirtz, Theresa and Flaßhove, Alexander and Rodenhausen, Aaron N. and Vajen, Tanja and Heinzmann, Alexandra C. A. and Schmitz, Sophia Marie-Therese and Abu Jhaisha, Samira and Röth, Anjali Anna Joy and Koenen, Rory R. and Sahin, Hacer and Trautwein, Christian and Berres, Marie-Luise},
  title        = {{JAM}‐A is a multifaceted regulator in hepatic fibrogenesis, supporting {LSEC} integrity and stellate cell quiescence},
  journaltitle = {Liver international},
  year         = {2022},
  doi          = {10.1111/liv.15187},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B04,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {1185--1203},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:35129269},
  reportid     = {RWTH-2022-04260},
  url          = {https://publications.rwth-aachen.de/record/844848},
  volume       = {42},
}

@article{Brozat:848649,
  author       = {Brozat, Jonathan F. and Hanses, Frank and Haelberger, Martina and Stecher, Melanie and Dreher, Michael and Tometten, Lukas and Ruethrich, Maria M. and Vehreschild, Janne J. and Trautwein, Christian and Borgmann, Stefan and Vehreschild, Maria J. G. T. and Jakob, Carolin E. M. and Stallmach, Andreas and Wille, Kai and Hellwig, Kerstin and Isberner, Nora and Reuken, Philipp A. and Geisler, Fabian and Nattermann, Jacob and Bruns, Tony and study group, LEOSS},
  title        = {{COVID}‐19 mortality in cirrhosis is determined by cirrhosis‐associated comorbidities and extrahepatic organ failure: Results from the multinational {LEOSS} registry},
  journaltitle = {United european gastroenterology journal},
  year         = {2022},
  doi          = {10.1002/ueg2.12232},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {409--424},
  publisher    = {Wiley},
  pubmed       = {pmid:35482663},
  reportid     = {RWTH-2022-06188},
  url          = {https://publications.rwth-aachen.de/record/848649},
  volume       = {10},
}

@article{Bruneau:855366,
  author       = {Bruneau, Alix and Guillot, Adrien and Tacke, Frank},
  title        = {Macrophages in cholangiopathies},
  journaltitle = {Current opinion in gastroenterology},
  year         = {2022},
  doi          = {10.1097/MOG.0000000000000814},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Philadelphia, Pa},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {114--120},
  publisher    = {Lippincott Williams \& Wilkins},
  pubmed       = {pmid:35098932},
  reportid     = {RWTH-2022-10183},
  url          = {https://publications.rwth-aachen.de/record/855366},
  volume       = {38},
}

@article{Candels:849815,
  author       = {Candels, Lena Susanna and Becker, Svea and Trautwein, Christian},
  title        = {{PLA}2G7: a new player in shaping energy metabolism and lifespan},
  journaltitle = {Signal transduction and targeted therapy},
  year         = {2022},
  doi          = {10.1038/s41392-022-01052-5},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {195},
  publisher    = {Macmillan Publishers, part of Springer Nature},
  reportid     = {RWTH-2022-07048},
  url          = {https://publications.rwth-aachen.de/record/849815},
  volume       = {7},
}

@article{Clavel:836462,
  author       = {Clavel, Thomas and Horz, Hans-Peter and Segata, Nicola and Vehreschild, Maria J. G. T.},
  title        = {Next steps after 15 stimulating years of human gut microbiome research},
  journaltitle = {Microbial biotechnology},
  year         = {2022},
  doi          = {10.1111/1751-7915.13970},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {164--175},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:34818454},
  reportid     = {RWTH-2021-11328},
  url          = {https://publications.rwth-aachen.de/record/836462},
  volume       = {15},
}

@article{Colyn:848139,
  author       = {Colyn, Leticia and Alvarez-Sola, Gloria and Latasa, M. Ujue and Uriarte, Iker and Herranz, Jose M. and Arechederra, Maria and Vlachogiannis, George and Rae, Colin and Pineda-Lucena, Antonio and Casadei-Gardini, Andrea and Pedica, Federica and Aldrighetti, Luca and López-López, Angeles and López-Gonzálvez, Angeles and Barbas, Coral and Ciordia, Sergio and Van Liempd, Sebastiaan M. and Falcón-Pérez, Juan M. and Urman, Jesus and Sangro, Bruno and Vicent, Silve and Iraburu, Maria J. and Prosper, Felipe and Nelson, Leonard J. and Banales, Jesus M. and Martinez-Chantar, Maria Luz and Marin, Jose J. G. and Braconi, Chiara and Trautwein, Christian and Corrales, Fernando J. and Cubero, F. Javier and Berasain, Carmen and Fernandez-Barrena, Maite G. and Avila, Matias A.},
  title        = {New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and {KRAS} co-opted epigenetic mediators driving metabolic reprogramming},
  journaltitle = {Journal of experimental \& clinical cancer research},
  year         = {2022},
  doi          = {10.1186/s13046-022-02386-2},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {183},
  publisher    = {Springer},
  pubmed       = {pmid:35619118},
  reportid     = {RWTH-2022-05786},
  url          = {https://publications.rwth-aachen.de/record/848139},
  volume       = {41},
}

@article{Fries:848142,
  author          = {Fries, Charlotte M. and Haange, Sven-Bastiaan and Rolle-Kampczyk, Ulrike and Till, Andreas and Lammert, Mathis and Grasser, Linda and Medawar, Evelyn and Dietrich, Arne and Horstmann, Annette and von Bergen, Martin and Fenske, Wiebke K.},
  title           = {Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery},
  journaltitle    = {Metabolites},
  year            = {2022},
  doi             = {10.3390/metabo12050417},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A05},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {5},
  pages           = {417},
  publisher       = {MDPI},
  pubmed          = {pmid:35629921},
  reportid        = {RWTH-2022-05789},
  url             = {https://publications.rwth-aachen.de/record/848142},
  volume          = {12},
}

@article{Fromme:861926,
  author       = {Fromme, Malin and Schneider, Carolin Victoria and Schlapbach, Christoph and Cazzaniga, Simone and Trautwein, Christian and Rader, Dan J. and Borradori, Luca and Strnad, Pavel},
  title        = {Comorbidities in lichen planus by phenome‐wide association study in two biobank population cohorts},
  journaltitle = {British journal of dermatology},
  year         = {2022},
  doi          = {10.1111/bjd.21762},
  keywords     = {,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {722--729},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:35819183},
  reportid     = {RWTH-CONV-249897},
  url          = {https://publications.rwth-aachen.de/record/861926},
  volume       = {187},
}

@article{Gardey:844492,
  author       = {Gardey, Elena and Sobotta, Fabian H. and Quickert, Stefanie and Bruns, Tony and Brendel, Johannes C. and Stallmach, Andreas},
  title        = {{ROS}-Sensitive Polymer Micelles for Selective Degradation in Primary Human Monocytes from Patients with Active {IBD}},
  journaltitle = {Macromolecular bioscience},
  year         = {2022},
  doi          = {10.1002/mabi.202100482},
  keywords     = {,CRC1382-Project B07},
  location     = {Weinheim},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {2100482},
  publisher    = {Wiley-VCH},
  pubmed       = {pmid:35068059},
  reportid     = {RWTH-2022-03962},
  shortjournal = {MBS},
  url          = {https://publications.rwth-aachen.de/record/844492},
  volume       = {22},
}

@article{Ghallab:855677,
  author       = {Ghallab, Ahmed and Hassan, Reham and Hofmann, Ute and Friebel, Adrian and Hobloss, Zaynab and Brackhagen, Lisa and Begher-Tibbe, Brigitte and Myllys, Maiju and Reinders, Joerg and Overbeck, Nina and Sezgin, Selahaddin and Zühlke, Sebastian and Seddek, Abdel-latif and Murad, Walaa and Brecklinghaus, Tim and Kappenberg, Franziska and Rahnenführer, Jörg and González, Daniela and Goldring, Christopher and Copple, Ian M. and Marchan, Rosemarie and Longerich, Thomas and Vucur, Mihael and Lüdde, Tom and Urban, Stephan and Canbay, Ali and Schreiter, Thomas and Trauner, Michael and Akakpo, Jephte Y. and Olyaee, Mojtaba and Curry, Steven C. and Sowa, Jan-Peter and Jaeschke, Hartmut and Hoehme, Stefan and Hengstler, Jan G.},
  title        = {Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity},
  journaltitle = {Journal of hepatology},
  year         = {2022},
  doi          = {10.1016/j.jhep.2022.01.020},
  keywords     = {,CRC1382-Project A01},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {71--83},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:35131407},
  reportid     = {RWTH-2022-10358},
  url          = {https://publications.rwth-aachen.de/record/855677},
  volume       = {77},
}

@article{Grube:853586,
  author       = {Grube, Julia and Woitok, Marius Maximilian and Mohs, Antje and Erschfeld, Stephanie and Lynen, Celina and Trautwein, Christian and Otto, Tobias},
  title        = {{ACSL}4-dependent ferroptosis does not represent a tumor-suppressive mechanism but {ACSL}4 rather promotes liver cancer progression},
  journaltitle = {Cell death \& disease},
  year         = {2022},
  doi          = {10.1038/s41419-022-05137-5},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {704},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:35963845},
  reportid     = {RWTH-2022-08947},
  url          = {https://publications.rwth-aachen.de/record/853586},
  volume       = {13},
}

@article{Guo:851958,
  author       = {Guo, Feifei and Estévez-Vázquez, Olga and Benedé-Ubieto, Raquel and Maya-Miles, Douglas and Zheng, Kang and Gallego-Durán, Rocío and Rojas, Ángela and Ampuero, Javier and Romero-Gómez, Manuel and Philip, Kaye and Egbuniwe, Isioma U. and Chen, Chaobo and Simon, Jorge and Delgado, Teresa C. and Martínez-Chantar, María Luz and Sun, Jie and Reißing, Johanna and Bruns, Tony and Lamas-Paz, Arantza and Moral, Manuel Gómez Del and Woitok, Marius Maximilian and Vaquero, Javier and Regueiro, José R. and Liedtke, Christian and Trautwein, Christian and Bañares, Rafael and Cubero, Francisco Javier and Nevzorova, Yulia A.},
  title        = {A Shortcut from Metabolic-Associated Fatty Liver Disease ({MAFLD}) to Hepatocellular Carcinoma ({HCC}): c-{MYC} a Promising Target for Preventative Strategies and Individualized Therapy},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14010192},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {192},
  publisher    = {MDPI},
  pubmed       = {pmid:35008356},
  reportid     = {RWTH-CONV-249046},
  url          = {https://publications.rwth-aachen.de/record/851958},
  volume       = {14},
}

@article{Haange:849341,
  author          = {Haange, Sven-Bastiaan and Till, Andreas and Bergh, Per-Olof and Fauler, Günter and Gigl, Michael and Löfgren-Sandblom, Anita and Schaap, Frank G. and Clavel, Thomas and Trautwein, Christian and Fenske, Wiebke and Kleigrewe, Karin and Marschall, Hanns-Ulrich and Olde Damink, Steven W. M. and Moustafa, Tarek and von Bergen, Martin and Rolle-Kampczyk, Ulrike},
  title           = {Ring Trial on Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and Reproducibility},
  journaltitle    = {Metabolites},
  year            = {2022},
  doi             = {10.3390/metabo12070583},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A07,CRC1382-Project A07,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A05},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {7},
  pages           = {583},
  publisher       = {MDPI},
  pubmed          = {pmid:35888707},
  reportid        = {RWTH-2022-06738},
  url             = {https://publications.rwth-aachen.de/record/849341},
  volume          = {12},
}

@article{Hitch:855027,
  author       = {Hitch, Thomas C. A. and Hall, Lindsay J. and Walsh, Sarah Kate and Leventhal, Gabriel E. and Slack, Emma and de Wouters, Tomas and Walter, Jens and Clavel, Thomas},
  title        = {Microbiome-based interventions to modulate gut ecology and the immune system},
  journaltitle = {Mucosal immunology},
  year         = {2022},
  doi          = {10.1038/s41385-022-00564-1},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1095--1113},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2022-09939},
  url          = {https://publications.rwth-aachen.de/record/855027},
  volume       = {15},
}

@article{Kleinjans:852859,
  author       = {Kleinjans, Moritz and Schneider, Carolin Victoria and Bruns, Tony and Strnad, Pavel},
  title        = {Phenome of coeliac disease vs. inflammatory bowel disease},
  journaltitle = {Scientific reports},
  year         = {2022},
  doi          = {10.1038/s41598-022-18593-y},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {14572},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  reportid     = {RWTH-2022-08414},
  url          = {https://publications.rwth-aachen.de/record/852859},
  volume       = {12},
}

@article{Krieg:860347,
  author       = {Krieg, Sarah and Essing, Tobias and Krieg, Andreas and Roderburg, Christoph and Lüdde, Tom and Loosen, Sven H.},
  title        = {Recent Trends and In-Hospital Mortality of Transarterial Chemoembolization ({TACE}) in Germany: A Systematic Analysis of Hospital Discharge Data between 2010 and 2019},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14092088},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {2088},
  publisher    = {MDPI},
  pubmed       = {pmid:35565218},
  reportid     = {RWTH-2022-11341},
  url          = {https://publications.rwth-aachen.de/record/860347},
  volume       = {14},
}

@article{Labiano:855675,
  author       = {Labiano, Ibone and Agirre-Lizaso, Aloña and Olaizola, Paula and Echebarria, Anne and Huici-Izagirre, Maider and Olaizola, Irene and Esparza-Baquer, Aitor and Sharif, Omar and Hijona, Elizabeth and Milkiewicz, Piotr and Milkiewicz, Malgorzata and González-Romero, Francisco and Aspichueta, Patricia and Monte, Maria J. and Marin, Jose J. G. and Vucur, Mihael and Lüdde, Tom and Marzioni, Marco and Mann, Derek A. and Bujanda, Luis and Rodrigues, Pedro M. and Banales, Jesus M. and Perugorria, Maria J.},
  title        = {{TREM}-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation},
  journaltitle = {Journal of hepatology},
  year         = {2022},
  doi          = {10.1016/j.jhep.2022.05.044},
  keywords     = {,CRC1382-Project A01},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {991--1004},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:35750136},
  reportid     = {RWTH-2022-10356},
  url          = {https://publications.rwth-aachen.de/record/855675},
  volume       = {77},
}

@article{Laschtowitz:1010393,
  author          = {Laschtowitz, Alena and Tacke, Frank},
  title           = {Many roads lead to Rome: The {FGF}4–{AMP}‐activated protein kinase–Caspase 6 signal axis in {NAFLD} and {NASH}},
  journaltitle    = {Hepatology},
  year            = {2022},
  doi             = {10.1002/hep.32454},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {911--913},
  publisher       = {Wolters Kluwer Health},
  reportid        = {RWTH-2025-04074},
  url             = {https://publications.rwth-aachen.de/record/1010393},
  volume          = {76},
}

@article{Liu:852317,
  author       = {Liu, Dong and Heij, Lara and Czigany, Zoltan and Dahl, Edgar and Den Dulk, Marcel and Lang, Sven and Ulmer, Tom Florian and Neumann, Ulf Peter and Bednarsch, Jan},
  title        = {The prognostic value of neutrophil-to-lymphocyte ratio in cholangiocarcinoma},
  journaltitle = {Scientific reports},
  year         = {2022},
  doi          = {10.1038/s41598-022-16727-w},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {12691},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  pubmed       = {pmid:35879385},
  reportid     = {RWTH-2022-07982},
  subtitle     = {A systematic review and meta-analysis},
  url          = {https://publications.rwth-aachen.de/record/852317},
  volume       = {12},
}

@article{Liu:844276,
  author       = {Liu, Dong and Heij, Lara Rosaline and Czigany, Zoltan and Dahl, Edgar and Lang, Sven Arke and Ulmer, Tom Florian and Lüdde, Tom and Neumann, Ulf Peter and Bednarsch, Jan},
  title        = {The role of tumor-infiltrating lymphocytes in cholangiocarcinoma},
  journaltitle = {Journal of experimental \& clinical cancer research},
  year         = {2022},
  doi          = {10.1186/s13046-022-02340-2},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {127},
  publisher    = {Springer},
  reportid     = {RWTH-2022-03788},
  url          = {https://publications.rwth-aachen.de/record/844276},
  volume       = {41},
}

@article{Loosen:860344,
  author       = {Loosen, Sven H. and Essing, Tobias and Jördens, Markus and Koch, Alexander and Tacke, Frank and Knoefel, Wolfram T. and Bode, Johannes and Roderburg, Christoph and Lüdde, Tom},
  title        = {Current epidemiological trends and in-hospital mortality of acute pancreatitis in Germany: a systematic analysis of standardized hospital discharge data between 2008 and 2017},
  journaltitle = {Zeitschrift für Gastroenterologie},
  year         = {2022},
  doi          = {10.1055/a-1682-7621},
  keywords     = {,CRC1382-Project A01,CRC1382-Project B05},
  location     = {Stuttgart and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {310--319},
  publisher    = {Thieme},
  pubmed       = {pmid:34820807},
  reportid     = {RWTH-2022-11339},
  url          = {https://publications.rwth-aachen.de/record/860344},
  volume       = {60},
}

@article{Loosen:860338,
  author       = {Loosen, Sven H. and Halpaap, Justus Florian and Labuhn, Simon and Bednarsch, Jan and Alizai, Patrick Hamid and Roeth, Anjali A. and Lang, Sven A. and Vucur, Mihael and Kather, Jakob N. and Knoefel, Wolfram T. and Ulmer, Tom Florian and Neumann, Ulf Peter and Roderburg, Christoph and Lüdde, Tom},
  title        = {Golgi Protein 73 ({GP}73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14184428},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {18},
  pages        = {4428},
  publisher    = {MDPI},
  pubmed       = {pmid:36139589},
  reportid     = {RWTH-2022-11333},
  url          = {https://publications.rwth-aachen.de/record/860338},
  volume       = {14},
}

@article{Loosen:860346,
  author          = {Loosen, Sven H. and Jensen, Björn-Erik Ole and Tanislav, Christian and Lüdde, Tom and Roderburg, Christoph and Kostev, Karel},
  title           = {Obesity and lipid metabolism disorders determine the risk for development of long {COVID} syndrome: a cross-sectional study from 50,402 {COVID}-19 patients},
  journaltitle    = {Infection},
  year            = {2022},
  doi             = {10.1007/s15010-022-01784-0},
  journalsubtitle = {A journal of infectious disease},
  keywords        = {,CRC1382-Project A01},
  location        = {München},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {5},
  pages           = {1165--1170},
  publisher       = {Urban \& Vogel},
  pubmed          = {pmid:35355237},
  reportid        = {RWTH-2022-11340},
  url             = {https://publications.rwth-aachen.de/record/860346},
  volume          = {50},
}

@article{Loosen:860341,
  author       = {Loosen, Sven H. and Kostev, Karel and Jördens, Markus S. and Lüdde, Tom and Roderburg, Christoph},
  title        = {Overlap between irritable bowel syndrome and common gastrointestinal diagnoses: a retrospective cohort study of 29,553 outpatients in Germany},
  journaltitle = {BMC gastroenterology},
  year         = {2022},
  doi          = {10.1186/s12876-022-02118-y},
  keywords     = {,CRC1382-Project A01},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {48},
  publisher    = {BioMed Central},
  pubmed       = {pmid:35123405},
  reportid     = {RWTH-2022-11336},
  url          = {https://publications.rwth-aachen.de/record/860341},
  volume       = {22},
}

@article{Loosen:860343,
  author       = {Loosen, Sven H. and Roderburg, Christoph and Jördens, Markus S. and Fluegen, Georg and Lüdde, Tom and Kostev, Karel},
  title        = {Overweight and Obesity Determine the Risk for Gastrointestinal Cancer in a Sex-Dependent Manner: A Retrospective Cohort Study of 287,357 Outpatients in Germany},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14040931},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {931},
  publisher    = {MDPI},
  pubmed       = {pmid:35205678},
  reportid     = {RWTH-2022-11338},
  url          = {https://publications.rwth-aachen.de/record/860343},
  volume       = {14},
}

@article{Loosen:860348,
  author       = {Loosen, Sven H. and Ulmer, Tom Florian and Labuhn, Simon and Bednarsch, Jan and Lang, Sven and Alizai, Patrick Hamid and Schneider, Anne Theres and Vucur, Mihael and Neumann, Ulf Peter and Lüdde, Tom and Roderburg, Christoph},
  title        = {Serum Levels of {CXCL}13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14174073},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {17},
  pages        = {4073},
  publisher    = {MDPI},
  pubmed       = {pmid:36077611},
  reportid     = {RWTH-2022-11342},
  url          = {https://publications.rwth-aachen.de/record/860348},
  volume       = {14},
}

@article{Murthy:838779,
  author       = {Murthy, Supriya and Karkossa, Isabel and Schmidt, Caroline and Hoffmann, Anne and Hagemann, Tobias and Rothe, Kathrin and Seifert, Olga and Anderegg, Ulf and von Bergen, Martin and Schubert, Kristin and Rossol, Manuela},
  title        = {Danger signal extracellular calcium initiates differentiation of monocytes into {SPP}1/osteopontin-producing macrophages},
  journaltitle = {Cell death \& disease},
  year         = {2022},
  doi          = {10.1038/s41419-022-04507-3},
  keywords     = {,CRC1382-Project A05},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {53},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:35022393},
  reportid     = {RWTH-2022-00755},
  url          = {https://publications.rwth-aachen.de/record/838779},
  volume       = {13},
}

@article{Pabst:836427,
  author       = {Pabst, Oliver and Izcue, Ana Maria},
  title        = {Secretory IgA},
  journaltitle = {Nature reviews / Gastroenterology \& hepatology},
  year         = {2022},
  doi          = {10.1038/s41575-021-00563-w},
  keywords     = {,CRC1382-Project B08,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {Basingstoke},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {149--150},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2021-11302},
  subtitle     = {Controlling the gut microbiota},
  url          = {https://publications.rwth-aachen.de/record/836427},
  volume       = {19},
}

@article{Pedersen:854665,
  author          = {Pedersen, Kristian Jensen and Haange, Sven-Bastiaan and Žížalová, Kateřina and Viehof, Alina and Clavel, Thomas and Leniček, Martin and Engelmann, Beatrice and Wick, Lukas Y. and Schaap, Frank G. and Jehmlich, Nico and Rolle-Kampczyk, Ulrike and von Bergen, Martin},
  title           = {Eggerthella lenta {DSM} 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation of Bile Acids},
  journaltitle    = {Microorganisms},
  year            = {2022},
  doi             = {10.3390/microorganisms10102025},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A07,CRC1382-Project A05,CRC1382-Project A05},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {10},
  pages           = {2025},
  publisher       = {MDPI},
  pubmed          = {pmid:36296301},
  reportid        = {RWTH-2022-09702},
  url             = {https://publications.rwth-aachen.de/record/854665},
  volume          = {10},
}

@article{Peiseler:1010343,
  author       = {Peiseler, Moritz and Schwabe, Robert and Hampe, Jochen and Kubes, Paul and Heikenwälder, Mathias and Tacke, Frank},
  title        = {Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits},
  journaltitle = {Journal of hepatology},
  year         = {2022},
  doi          = {10.1016/j.jhep.2022.06.012},
  keywords     = {,CRC1382-Project B05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {1136--1160},
  publisher    = {Elsevier Science},
  reportid     = {RWTH-2025-04031},
  url          = {https://publications.rwth-aachen.de/record/1010343},
  volume       = {77},
}

@article{Puengel:854666,
  author       = {Puengel, Tobias and Lefere, Sander and Hundertmark, Jana and Kohlhepp, Marlene and Penners, Christian and Van de Velde, Frederique and Lapauw, Bruno and Hoorens, Anne and Devisscher, Lindsey and Geerts, Anja and Boehm, Stephanie and Zhao, Qihong and Krupinski, John and Charles, Edgar D. and Zinker, Bradley and Tacke, Frank},
  title        = {Combined Therapy with a {CCR}2/{CCR}5 Antagonist and {FGF}21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis},
  journaltitle = {International journal of molecular sciences},
  year         = {2022},
  doi          = {10.3390/ijms23126696},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {6696},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:35743140},
  reportid     = {RWTH-2022-09703},
  url          = {https://publications.rwth-aachen.de/record/854666},
  volume       = {23},
}

@article{Puengel:1010345,
  author       = {Puengel, Tobias and Liu, Hanyang and Guillot, Adrien and Heymann, Felix and Tacke, Frank and Peiseler, Moritz},
  title        = {Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease},
  journaltitle = {International journal of molecular sciences},
  year         = {2022},
  doi          = {10.3390/ijms23052668},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {2668},
  publisher    = {Molecular Diversity Preservation International},
  reportid     = {RWTH-2025-04032},
  url          = {https://publications.rwth-aachen.de/record/1010345},
  volume       = {23},
}

@article{Puengel:839874,
  author          = {Puengel, Tobias and Weber, Beate and Wirtz, Theresa and Buendgens, Lukas and Loosen, Sven H. and Geisler, Lukas and Özdirik, Burcin and Hamesch, Karim and Jhaisha, Samira Abu and Brozat, Jonathan F. and Hohlstein, Philipp and Eisert, Albrecht and Yagmur, Eray and Trautwein, Christian and Tacke, Frank and Koch, Alexander},
  title           = {Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (s{RANKL}) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients},
  journaltitle    = {Diagnostics},
  year            = {2022},
  doi             = {10.3390/diagnostics12010062},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {1},
  pages           = {62},
  publisher       = {MDPI},
  pubmed          = {pmid:35054232},
  reportid        = {RWTH-2022-00904},
  url             = {https://publications.rwth-aachen.de/record/839874},
  volume          = {12},
}

@article{Quickert:848650,
  author       = {Quickert, Stefanie and Würstle, Silvia and Reuken, Philipp A. and Hagel, Stefan and Schneider, Jochen and Schmid, Roland M. and Neugebauer, Sophie and Stallmach, Andreas and Bruns, Tony},
  title        = {Real-World Effectiveness of Piperacillin/Tazobactam with and without Linezolid for Spontaneous Bacterial Peritonitis},
  journaltitle = {Digestive diseases},
  year         = {2022},
  doi          = {10.1159/000522259},
  keywords     = {,CRC1382-Project B07},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {777--786},
  publisher    = {Karger},
  reportid     = {RWTH-2022-06189},
  url          = {https://publications.rwth-aachen.de/record/848650},
  volume       = {40},
}

@article{Reuken:849793,
  author       = {Reuken, Philipp A. and Brozat, Jonathan F. and Quickert, Stefanie and Ibidapo-obe, Oluwatomi and Reißing, Johanna and Franz, Anika and Stengel, Sven and Teichgräber, Ulf K.-M. and Kiehntopf, Michael and Trautwein, Christian and Stallmach, Andreas and Koch, Alexander and Bruns, Tony},
  title        = {Soluble mannose receptor {CD}206 and von Willebrand factor are early biomarkers to identify patients at risk for severe or necrotizing acute pancreatitis},
  journaltitle = {Journal of Intensive Care},
  year         = {2022},
  doi          = {10.1186/s40560-022-00619-2},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {28},
  publisher    = {BioMed Central},
  pubmed       = {pmid:35690841},
  reportid     = {RWTH-2022-07031},
  url          = {https://publications.rwth-aachen.de/record/849793},
  volume       = {10},
}

@article{Richter:854987,
  author       = {Richter, Beate and Zafarnia, Sarah and Gremse, Felix and Kießling, Fabian and Scheuerlein, Hubert and Settmacher, Utz and Dahmen, Uta},
  title        = {Corrosion Cast and 3D Reconstruction of the Murine Biliary Tree After Biliary Obstruction},
  journaltitle = {Journal of Clinical and Experimental Hepatology},
  year         = {2022},
  doi          = {10.1016/j.jceh.2021.12.008},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {755--766},
  publisher    = {Elsevier},
  reportid     = {RWTH-2022-09907},
  subtitle     = {Quantitative Assessment and Comparison With 2D Histology},
  url          = {https://publications.rwth-aachen.de/record/854987},
  volume       = {12},
}

@article{Roderburg:860340,
  author       = {Roderburg, Christoph and Essing, Tobias and Kehmann, Linde and Krieg, Sarah and Labuhn, Simon and Kandler, Jennis and Lüdde, Tom and Loosen, Sven H.},
  title        = {Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14164038},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {16},
  pages        = {4038},
  publisher    = {MDPI},
  pubmed       = {pmid:36011031},
  reportid     = {RWTH-2022-11335},
  url          = {https://publications.rwth-aachen.de/record/860340},
  volume       = {14},
}

@article{Schneider:855007,
  author       = {Schneider, Annika R. P. and Schneider, Carolin Victoria and Schneider, Kai Markus and Baier, Vanessa and Schaper, Steffen and Diedrich, Christian and Coboeken, Katrin and Mayer, Hannah and Gu, Wenyi and Trebicka, Jonel and Blank, Lars Mathias and Burghaus, Rolf and Lippert, Joerg and Rader, Daniel J. and Thaiss, Christoph A. and Schlender, Jan-Frederik and Trautwein, Christian and Küpfer, Lars},
  title        = {Early prediction of decompensation ({EPOD}) score: Non-invasive determination of cirrhosis decompensation risk},
  journaltitle = {Liver international},
  year         = {2022},
  doi          = {10.1111/liv.15161},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A06,CRC1382-Project B09,CRC1382-Project A06,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A09},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {640--650},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:35007409},
  reportid     = {RWTH-2022-09924},
  url          = {https://publications.rwth-aachen.de/record/855007},
  volume       = {42},
}

@article{Schler:860350,
  author       = {Schöler, David and Kostev, Karel and Demir, Münevver and Luedde, Mark and Konrad, Marcel and Lüdde, Tom and Roderburg, Christoph and Loosen, Sven H.},
  title        = {An Elevated {FIB}-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany},
  journaltitle = {Journal of Clinical Medicine},
  year         = {2022},
  doi          = {10.3390/jcm11082214},
  keywords     = {,CRC1382-Project A01},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {2214},
  publisher    = {MDPI},
  pubmed       = {pmid:35456304},
  reportid     = {RWTH-2022-11344},
  url          = {https://publications.rwth-aachen.de/record/860350},
  volume       = {11},
}

@article{Strnad:855006,
  author       = {Strnad, Pavel and Mandorfer, Mattias and Choudhury, Gourab and Griffiths, William and Trautwein, Christian and Loomba, Rohit and Schluep, Thomas and Chang, Ting and Yi, Min and Given, Bruce D. and Hamilton, James C. and San Martin, Javier and Teckman, Jeffery H.},
  title        = {Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency},
  journaltitle = {The New England journal of medicine},
  year         = {2022},
  doi          = {10.1056/NEJMoa2205416},
  keywords     = {,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Waltham, Mass.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {514--524},
  publisher    = {MMS},
  pubmed       = {pmid:35748699},
  reportid     = {RWTH-2022-09923},
  url          = {https://publications.rwth-aachen.de/record/855006},
  volume       = {387},
}

@article{Thamm:850726,
  author       = {Thamm, Mirko and Rosenhain, Stefanie and Leonardic, Kevin and Höfter, Andreas and Kießling, Fabian and Osl, Franz and Pöschinger, Thomas and Gremse, Felix},
  title        = {Intrinsic Respiratory Gating for Simultaneous Multi-Mouse μ{CT} Imaging to Assess Liver Tumors},
  journaltitle = {Frontiers in medicine},
  year         = {2022},
  doi          = {10.3389/fmed.2022.878966},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {878966},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2022-07678},
  url          = {https://publications.rwth-aachen.de/record/850726},
  volume       = {9},
}

@article{Vonderlin:1010347,
  author       = {Vonderlin, Joscha and Tacke, Frank},
  title        = {A complex triad determining metabolic health: diet, host, and microbiome interaction},
  journaltitle = {The American journal of clinical nutrition},
  year         = {2022},
  doi          = {10.1093/ajcn/nqac180},
  keywords     = {,CRC1382-Project B05},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {848--850},
  publisher    = {Elsevier},
  reportid     = {RWTH-2025-04033},
  url          = {https://publications.rwth-aachen.de/record/1010347},
  volume       = {116},
}

@article{Wang:856972,
  author       = {Wang, Guanwu and Heij, Lara Rosaline and Liu, Dong and Dahl, Edgar and Lang, Sven Arke and Ulmer, Tom Florian and Lüdde, Tom and Neumann, Ulf Peter and Bednarsch, Jan},
  title        = {The Role of Single-Nucleotide Polymorphisms in Cholangiocarcinoma: A Systematic Review},
  journaltitle = {Cancers},
  year         = {2022},
  doi          = {10.3390/cancers14235969},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {23},
  pages        = {5969},
  publisher    = {MDPI},
  reportid     = {RWTH-2022-11284},
  url          = {https://publications.rwth-aachen.de/record/856972},
  volume       = {14},
}

@article{Wirth:1010349,
  author       = {Wirth, Eva K. and Puengel, Tobias and Spranger, Joachim and Tacke, Frank},
  title        = {Thyroid hormones as a disease modifier and therapeutic target in nonalcoholic steatohepatitis},
  journaltitle = {Expert review of endocrinology \& metabolism},
  year         = {2022},
  doi          = {10.1080/17446651.2022.2110864},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {425--434},
  publisher    = {Taylor \& Francis},
  reportid     = {RWTH-2025-04035},
  url          = {https://publications.rwth-aachen.de/record/1010349},
  volume       = {17},
}

@article{Yagmur:860407,
  author          = {Yagmur, Eray and Abu Jhaisha, Samira and Bündgens, Lukas and Sapundzhieva, Nadezhda and Brozat, Jonathan Frederik and Hohlstein, Philipp and Pollmanns, Maike and Koek, Ger H. and Weiskirchen, Ralf and Trautwein, Christian and Tacke, Frank and Wirtz, Theresa and Koch, Alexander},
  title           = {Clusterin Plasma Concentrations Are Decreased in Sepsis and Inversely Correlated with Established Markers of Inflammation},
  journaltitle    = {Diagnostics},
  year            = {2022},
  doi             = {10.3390/diagnostics12123010},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {12},
  pages           = {3010},
  publisher       = {MDPI},
  pubmed          = {pmid:36553017},
  reportid        = {RWTH-2022-11381},
  url             = {https://publications.rwth-aachen.de/record/860407},
  volume          = {12},
}

@inbook{Hundertmark:855241,
  author    = {Hundertmark, Jana and Berger, Hilmar and Tacke, Frank},
  title     = {Single Cell {RNA} Sequencing in {NASH}},
  year      = {2022},
  booktitle = {Non-Alcoholic steatohepatitis : methods and protocols / edited by Devanand Sarkar},
  doi       = {10.1007/978-1-0716-2128-8_15},
  keywords  = {,CRC1382-Project B05},
  location  = {New York, NY},
  note      = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages     = {181--202},
  publisher = {Humana Press},
  reportid  = {RWTH-2022-10103},
  series    = {Methods in molecular biology},
  url       = {https://publications.rwth-aachen.de/record/855241},
  volume    = {2455},
}

@misc{vonBergen:1027089,
  author   = {von Bergen, Martin},
  title    = {Danger signal initiates differentiation of monocytes into osteopontin‑producing macrophages {II} (human)},
  year     = {2022},
  keywords = {,CRC1382-Project A05},
  note     = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  reportid = {RWTH-2026-01203},
  url      = {https://publications.rwth-aachen.de/record/1027089},
}

@misc{vonBergen:1027092,
  author   = {von Bergen, Martin},
  title    = {Danger signal initiates differentiation of monocytes into osteopontin‑producing macrophages {III} (human)},
  year     = {2022},
  keywords = {,CRC1382-Project A05},
  note     = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  reportid = {RWTH-2026-01206},
  url      = {https://publications.rwth-aachen.de/record/1027092},
}

@misc{vonBergen:1027094,
  author   = {von Bergen, Martin},
  title    = {Project {PXD}026888},
  year     = {2022},
  keywords = {,CRC1382-Project A05},
  note     = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  reportid = {RWTH-2026-01208},
  url      = {https://publications.rwth-aachen.de/record/1027094},
}

@thesis{Leufgen:854036,
  author      = {Leufgen, Andrea},
  title       = {Intestinal and hepatic dendritic cells in the induction of tolerogenic responses},
  year        = {2022},
  abstract    = {Gut and liver build a functional entity, the so-called gut-liver axis, and act in concert to provide immunity and maintain tolerance to the gut microbiota as well as food derived antigens. Immune cells of the gut come into contact with luminal antigen through the epithelial layer, while the liver is exposed to oral antigen via portal vein blood. To perpetuate an overall tolerogenic status, two types of immune cells are of particular importance. Dendritic cells (DCs) are the main antigen presenting cells and therefore indispensable in both priming of protective immunity and maintaining immune tolerance to harmless antigen by inducing FoxP3+ regulatory T cells (Treg). In the steady state small intestine (SI), DCs induce unresponsiveness to orally delivered antigen, a mechanism referred to as oral tolerance. The liver also plays a role in tolerance induction and failure of oral tolerance can lead to inflammatory disorders such as food allergies or inflammatory bowel disease (IBD). In this thesis, we aimed to determine how DCs from gut and liver contribute to the induction of systemic tolerance. To address this, we examined if DCs of SI, colon and liver are able to pick up orally delivered antigen, migrate to draining lymph nodes (LNs) and activate T cells to become Treg. Furthermore we aimed to clarify how these Treg contribute to system-wide tolerance after oral antigen exposure by examining the homing patterns of newly activated T cells. We find that DCs from all three organs of the gut-liver axis are able to pick up oral antigen, subsequently migrate in lymph and present the antigen in draining LNs. While steady state DCs from SI, colon and liver showed overall phenotypic and transcriptomic similarity, they nevertheless exhibited several important differences, notably in directing the homing and differentiation of T cells. We found SI DCs to be most efficient in metabolising vitamin A derivatives which enhances their capacity to induce the retinoic acid (RA) dependent gut-homing factors CC type motif chemokine receptor (CCR) 9 and integrin alpha 4 beta 7 (Intα4β7) on newly activated T cells. Moreover, DCs migrating from the steady state SI, colon and liver were able to induce distinct T cell responses within the inductive compartment of the draining LNs. We established a photoconversion-based experimental model of in vivo T cell tracking and use it to demonstrate that oral administration of cognate antigen leads to T cell migration to distinct organs, dependent on the inductive LN compartment. Interestingly, our data shows that T cells primed in the SI-draining mesenteric LN (sMLN) subsequently migrate to SI, but also to colon and liver. In contrast, T cells activated in colon-draining MLN (cMLN) or liver-draining LNs (ldLNs) migrate exclusively to colon and liver, but not the SI. Notably, T cell homing correlated to a site-specific expression of chemotactic receptors. Thus, recently activated T cells that had migrated to the SI, colon and liver expressed high levels of CCR9, G protein coupled receptor (GPR) 15 and CXC-type motif chemokine receptor (CXCR) 3 respectively, suggesting a directed migration process to specific tissues orchestrated during T cell differentiation. Further studies will be necessary to characterise the molecular mechanisms that are responsible for the differential induction of chemokine receptor expression as well as delineate the relative contribution of the migrating DCs and the LN microenvironment in this process. However, in addition to directed homing, we found that a large proportion of T cells activated by oral antigen adopted a LN-resident phenotype. While their function or mechanisms of induction are unknown, one possibility is that these cells may be strategically positioned to prevent future adverse T cell priming and help maintain tolerance. In summary, our work contributes to a deeper understanding of the functionality of DCs and T cells within the gut-liver axis and extends the knowledge of how a tolerogenic environment is maintained, underlining the importance of a system-wide distribution of induced regulatory T cells after oral antigen exposure for future antigen encounters. Our data may aid in the development of new therapeutic strategies of for inflammatory disorders such as IBD or food allergies by characterising specific homing patterns of newly activated regulatory T cells after oral antigen exposure.},
  doi         = {10.18154/RWTH-2022-09262},
  institution = {RWTH Aachen University},
  location    = {Aachen},
  namea       = {Pabst, Oliver and Clavel, Thomas},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen,Diagramme},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2022-09262},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/854036},
}

@article{Asare:983108,
  author       = {Asare, Paul Tetteh and Lee, Chi-Hsien and Hürlimann, Vera and Teo, Youzheng and Cuénod, Aline and Akduman, Nermin and Gekeler, Cordula and Afrizal, Afrizal and Corthesy, Myriam and Kohout, Claire and Thomas, Vincent and de Wouters, Tomas and Greub, Gilbert and Clavel, Thomas and Pamer, Eric G. and Egli, Adrian and Maier, Lisa and Vonaesch, Pascale},
  title        = {A {MALDI}-{TOF} {MS} library for rapid identification of human commensal gut bacteria from the class Clostridia},
  journaltitle = {Frontiers in microbiology},
  year         = {2023},
  doi          = {10.3389/fmicb.2023.1104707},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1104707},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:36896425},
  reportid     = {RWTH-CONV-253184},
  url          = {https://publications.rwth-aachen.de/record/983108},
  volume       = {14},
}

@article{Bachtler:982736,
  author       = {Bachtler, Nadine and Torres, Sandra and Ortiz, Cristina and Schierwagen, Robert and Tyc, Olaf and Hieber, Christoph and Berres, Marie-Luise and Meier, Caroline and Kraus, Nico and Zeuzem, Stefan and Nijmeijer, Bart and Pronk, Sebas and Trebicka, Jonel and Klein, Sabine},
  title        = {The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells},
  journaltitle = {PLOS ONE},
  year         = {2023},
  doi          = {10.1371/journal.pone.0270288},
  keywords     = {,CRC1382-Project B04,CRC1382-Project A09,CRC1382-Project A09,CRC1382-Project A09},
  location     = {San Francisco, Falifornia, US},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1--15},
  publisher    = {Public Library of Science},
  pubmed       = {pmid:36719899},
  reportid     = {RWTH-CONV-252809},
  url          = {https://publications.rwth-aachen.de/record/982736},
  volume       = {18},
}

@article{Becker:982715,
  author          = {Becker, Svea and Momoh, Jeffrey and Biancacci, Ilaria and Möckel, Diana and Wang, Qingbi and May, Jan-Niklas and Su, Huan and Candels, Lena Susanna and Berres, Marie-Luise and Kießling, Fabian and Hatting, Maximilian and Lammers, Twan and Trautwein, Christian},
  title           = {Intermittent Fasting Primes the Tumor Microenvironment and Improves Nanomedicine Delivery in Hepatocellular Carcinoma},
  journaltitle    = {Small},
  year            = {2023},
  doi             = {10.1002/smll.202208042},
  journalsubtitle = {Nano micro},
  keywords        = {,CRC1382-Project B04,CRC1382-Project A08,CRC1382-Project Q01,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Weinheim},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {43},
  pages           = {2208042},
  publisher       = {Wiley-VCH},
  pubmed          = {pmid:37376850},
  reportid        = {RWTH-CONV-252778},
  url             = {https://publications.rwth-aachen.de/record/982715},
  volume          = {19},
}

@article{Cai:1010353,
  author       = {Cai, Xiurong and Tacke, Frank and Guillot, Adrien and Liu, Hanyang},
  title        = {Cholangiokines: undervalued modulators in the hepatic microenvironment},
  journaltitle = {Frontiers in immunology},
  year         = {2023},
  doi          = {10.3389/fimmu.2023.1192840},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1192840},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2025-04038},
  url          = {https://publications.rwth-aachen.de/record/1010353},
  volume       = {14},
}

@article{Chang:888760,
  author       = {Chang, Xinwei and Korenblik, Remon and Olij, Bram and Knapen, Robrecht R. M. M. and van der Leij, Christiaan and Heise, Daniel and den Dulk, Marcel and Neumann, Ulf Peter and Schaap, Frank G. and van Dam, Ronald M. and Olde Damink, Steven W. M.},
  title        = {Influence of cholestasis on portal vein embolization-induced hypertrophy of the future liver remnant},
  journaltitle = {Langenbeck's archives of surgery},
  year         = {2023},
  doi          = {10.1007/s00423-023-02784-w},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A07,CRC1382-Project A07},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {54},
  publisher    = {Springer},
  pubmed       = {pmid:36680689},
  reportid     = {RWTH-2023-00784},
  url          = {https://publications.rwth-aachen.de/record/888760},
  volume       = {408},
}

@article{Eschrich:1010361,
  author       = {Eschrich, Johannes and Kobus, Zuzanna and Geisel, Dominik and Halskov, Sebastian and Roßner, Florian and Roderburg, Christoph and Mohr, Raphael and Tacke, Frank},
  title        = {The Diagnostic Approach towards Combined Hepatocellular-Cholangiocarcinoma—State of the Art and Future Perspectives},
  journaltitle = {Cancers},
  year         = {2023},
  doi          = {10.3390/cancers15010301},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {301},
  publisher    = {MDPI},
  reportid     = {RWTH-2025-04045},
  url          = {https://publications.rwth-aachen.de/record/1010361},
  volume       = {15},
}

@article{Essing:954429,
  author       = {Essing, Tobias and Bock, Hans and Wieland, Björn and Fluegen, Georg and Bednarsch, Jan and Bode, Johannes G. and Neumann, Ulf Peter and Roderburg, Christoph and Loosen, Sven H. and Lüdde, Tom},
  title        = {Clinical determinants of hospital mortality in liver failure},
  journaltitle = {Zeitschrift für Gastroenterologie},
  year         = {2023},
  doi          = {10.1055/a-2016-9061},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Stuttgart and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {1472--1483},
  publisher    = {Thieme},
  pubmed       = {pmid:36972596},
  reportid     = {RWTH-2023-03198},
  subtitle     = {A comprehensive analysis of 62,717 patients},
  url          = {https://publications.rwth-aachen.de/record/954429},
  volume       = {61},
}

@article{Fidelle:977042,
  author       = {Fidelle, Marine and Rauber, Conrad and Alves Costa Silva, Carolina and Tian, Ai-Ling and Lahmar, Imran and de La Varende, Anne-Laure Mallard and Zhao, Liwei and Thelemaque, Cassandra and Lebhar, Isabelle and Messaoudene, Meriem and Pizzato, Eugenie and Birebent, Roxanne and Mbogning Fonkou, Maxime Descartes and Zoppi, Silvia and Reni, Anna and Dalban, Cécile and Leduc, Marion and Ferrere, Gladys and Durand, Sylvère and Ly, Pierre and Silvin, Aymeric and Mulder, Kevin and Dutertre, Charles-Antoine and Ginhoux, Florent and Yonekura, Satoru and Roberti, Maria Paula and Tidjani-Alou, Maryam and Terrisse, Safae and Chen, Jianzhou and Kepp, Oliver and Schippers, Angela and Wagner, Norbert and Suárez-Gosálvez, Javier and Kobold, Sebastian and Fahrner, Jean-Eudes and Richard, Corentin and Bosq, Jacques and Lordello, Leonardo and Vitali, Giacomo and Galleron, Nathalie and Quinquis, Benoît and Le Chatelier, Emmanuelle and Blanchard, Lucas and Girard, Jean-Philippe and Jarry, Anne and Gervois, Nadine and Godefroy, Emmanuelle and Labarrière, Nathalie and Koschny, Ronald and Daillère, Romain and Besse, Benjamin and Truntzer, Caroline and Ghiringhelli, François and Coatnoan, Nicolas and Mhanna, Vanessa and Klatzmann, David and Drubay, Damien and Albiges, Laurence and Thomas, Andrew Maltez and Segata, Nicola and Danlos, François-Xavier and Marabelle, Aurélien and Routy, Bertrand and Derosa, Lisa and Kroemer, Guido and Zitvogel, Laurence},
  title        = {A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers},
  journaltitle = {Science / Science now},
  year         = {2023},
  doi          = {10.1126/science.abo2296},
  keywords     = {,CRC1382-Project B02,CRC1382-Project B02},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6649},
  pages        = {eabo2296},
  publisher    = {American Association for the Advancement of Science},
  pubmed       = {pmid:37289890},
  reportid     = {RWTH-2024-00552},
  url          = {https://publications.rwth-aachen.de/record/977042},
  volume       = {380},
}

@article{Franz:982725,
  author       = {Franz, Anika and Reuken, Philipp A. and Guliyeva, Sura and Rose, Michael and Boden, Katharina and Stallmach, Andreas and Bruns, Tony},
  title        = {Early ribavirin for hepatitis E virus infection in patients receiving immunosuppressive therapy},
  journaltitle = {The journal of international medical research},
  year         = {2023},
  doi          = {10.1177/03000605231187941},
  keywords     = {,CRC1382-Project B07},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {[1]--13},
  publisher    = {Sage},
  pubmed       = {pmid:37523153},
  reportid     = {RWTH-CONV-252788},
  subtitle     = {A retrospective, observational study},
  url          = {https://publications.rwth-aachen.de/record/982725},
  volume       = {51},
}

@article{Ghait:982712,
  author       = {Ghait, Mohamed and Duduskar, Shivalee N. and Rooney, Michael and Häfner, Norman and Reng, Laura and Göhrig, Bianca and Reuken, Philipp A. and Bloos, Frank and Bauer, Michael and Sponholz, Christoph and Bruns, Tony and Rubio, Ignacio},
  title        = {The non-canonical inflammasome activators Caspase-4 and Caspase-5 are differentially regulated during immunosuppression-associated organ damage},
  journaltitle = {Frontiers in immunology},
  year         = {2023},
  doi          = {10.3389/fimmu.2023.1239474},
  keywords     = {,CRC1382-Project B07},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1--13},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:38106412},
  reportid     = {RWTH-CONV-252775},
  url          = {https://publications.rwth-aachen.de/record/982712},
  volume       = {14},
}

@article{Gui:959867,
  author       = {Gui, Wenfang and Hole, Mikal Jacob and Molinaro, Antonio and Edlund, Karolina and Jørgensen, Kristin K. and Su, Huan and Begher-Tibbe, Brigitte and Gaßler, Nikolaus and Schneider, Carolin Victoria and Muthukumarasamy, Uthayakumar and Mohs, Antje and Liao, Lijun and Jaeger, Julius and Mertens, Christian J. and Bergheim, Ina and Strowig, Till and Hengstler, Jan G. and Hov, Johannes R. and Marschall, Hanns-Ulrich and Trautwein, Christian and Schneider, Kai Markus},
  title        = {Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis},
  journaltitle = {Nature Communications},
  year         = {2023},
  doi          = {10.1038/s41467-023-38840-8},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A06,CRC1382-Project A08},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {3304},
  publisher    = {Nature Publishing Group UK},
  reportid     = {RWTH-2023-05879},
  url          = {https://publications.rwth-aachen.de/record/959867},
  volume       = {14},
}

@article{Guillaume:889189,
  author       = {Guillaume, Joel and Leufgen, Andrea and Hager, Fabian Tobias and Pabst, Oliver and Cerovic, Vuk},
  title        = {{MHCII} expression on gut macrophages supports T cell homeostasis and is regulated by microbiota and ontogeny},
  journaltitle = {Scientific reports},
  year         = {2023},
  doi          = {10.1038/s41598-023-28554-8},
  keywords     = {,CRC1382-Project B03,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {1509},
  publisher    = {Macmillan Publishers Limited, part of Springer Nature},
  pubmed       = {pmid:36707699},
  reportid     = {RWTH-2023-01011},
  url          = {https://publications.rwth-aachen.de/record/889189},
  volume       = {13},
}

@article{Guillot:918232,
  author          = {Guillot, Adrien and Winkler, Marc and Silva Afonso, Milessa and Aggarwal, Abhishek and Lopez, David and Berger, Hilmar and Kohlhepp, Marlene S. and Liu, Hanyang and Özdirik, Burcin and Eschrich, Johannes and Ma, Jing and Peiseler, Moritz and Heymann, Felix and Pendem, Swetha and Mahadevan, Sangeetha and Gao, Bin and Diehl, Lauri and Gupta, Ruchi and Tacke, Frank},
  title           = {Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression},
  journaltitle    = {Hepatology},
  year            = {2023},
  doi             = {10.1097/HEP.0000000000000270},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {1},
  pages           = {150--166},
  publisher       = {Wolters Kluwer Health},
  reportid        = {RWTH-2023-01195},
  url             = {https://publications.rwth-aachen.de/record/918232},
  volume          = {78},
}

@article{Gurbuz:863057,
  author       = {Gurbuz, Berivan and Guldiken, Nurdan and Reuken, Philipp and Fu, Lei and Remih, Katharina and Preisinger, Christian and Brůha, Radan and Leníček, Martin and Petrtýl, Jaromír and Reißing, Johanna and Aly, Mahmoud and Fromme, Malin and Zhou, Biaohuan and Karkossa, Isabel and Schubert, Kristin and von Bergen, Martin and Stallmach, Andreas and Bruns, Tony and Strnad, Pavel},
  title        = {Biomarkers of hepatocellular synthesis in patients with decompensated cirrhosis},
  journaltitle = {Hepatology international},
  year         = {2023},
  doi          = {10.1007/s12072-022-10473-x},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A03,CRC1382-Project A03,CRC1382-Project A05},
  location     = {New York, NY and Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {698--708},
  publisher    = {Springer},
  pubmed       = {pmid:36652164},
  reportid     = {RWTH-2023-00705},
  url          = {https://publications.rwth-aachen.de/record/863057},
  volume       = {17},
}

@article{Hammerich:959097,
  author       = {Hammerich, Linda and Shevchenko, Yaroslava and Knorr, Jana and Werner, Wiebke and Bruneau, Alix and Tacke, Frank},
  title        = {Resolving 31 colors on a standard 3‐laser full spectrum flow cytometer for immune monitoring of human blood samples},
  journaltitle = {Cytometry / B},
  year         = {2023},
  doi          = {10.1002/cyto.b.22126},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {367--373},
  publisher    = {Wiley-Liss},
  pubmed       = {pmid:37209003},
  reportid     = {RWTH-2023-05568},
  url          = {https://publications.rwth-aachen.de/record/959097},
  volume       = {104},
}

@article{Hammerich:1010375,
  author       = {Hammerich, Linda and Tacke, Frank},
  title        = {Hepatic inflammatory responses in liver fibrosis},
  journaltitle = {Nature reviews / Gastroenterology \& hepatology},
  year         = {2023},
  doi          = {10.1038/s41575-023-00807-x},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Basingstoke},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {633--646},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2025-04057},
  url          = {https://publications.rwth-aachen.de/record/1010375},
  volume       = {20},
}

@article{Heymann:982836,
  author       = {Heymann, Felix and Mossanen, Jana Christina and Peiseler, Moritz and Niemietz, Patricia Maria and Araujo David, Bruna and Krenkel, Oliver and Liepelt, Anke and Batista Carneiro, Matheus and Kohlhepp, Marlene S. and Kubes, Paul and Tacke, Frank},
  title        = {Hepatic C-X-C chemokine receptor type 6–expressing innate lymphocytes limit detrimental myeloid hyperactivation in acute liver injury},
  journaltitle = {Hepatology communications},
  year         = {2023},
  doi          = {10.1097/HC9.0000000000000102},
  keywords     = {,CRC1382-Project B05},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {e0102},
  publisher    = {Wolters Kluwer Health},
  pubmed       = {pmid:36972392},
  reportid     = {RWTH-CONV-252914},
  url          = {https://publications.rwth-aachen.de/record/982836},
  volume       = {7},
}

@article{Hohlstein:953717,
  author          = {Hohlstein, Philipp and Brozat, Jonathan Frederik and Schuler, Julia and Abu Jhaisha, Samira and Pollmanns, Maike and Bündgens, Lukas and Wirtz, Theresa and Yagmur, Eray and Hamesch, Karim and Weiskirchen, Ralf and Tacke, Frank and Trautwein, Christian and Koch, Alexander},
  title           = {Secreted Frizzled Related Protein 5 ({SFRP}5) Serum Levels Are Decreased in Critical Illness and Sepsis and Are Associated with Short-Term Mortality},
  journaltitle    = {Biomedicines},
  year            = {2023},
  doi             = {10.3390/biomedicines11020313},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {313},
  publisher       = {MDPI},
  pubmed          = {pmid:36830849},
  reportid        = {RWTH-CONV-251232},
  url             = {https://publications.rwth-aachen.de/record/953717},
  volume          = {11},
}

@article{IbidapoObe:982723,
  author       = {Ibidapo-Obe, Oluwatomi and Bruns, Tony},
  title        = {Tissue-resident and innate-like T cells in patients with advanced chronic liver disease},
  journaltitle = {JHEP reports},
  year         = {2023},
  doi          = {10.1016/j.jhepr.2023.100812},
  keywords     = {,CRC1382-Project B07},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {100812},
  publisher    = {Elsevier},
  pubmed       = {pmid:37691689},
  reportid     = {RWTH-CONV-252803},
  url          = {https://publications.rwth-aachen.de/record/982723},
  volume       = {5},
}

@article{Kaur:1010363,
  author       = {Kaur, Savneet and Kidambi, Srivatsan and Ortega-Ribera, Martí and Thuy, Le Thi Thanh and Nieto, Natalia and Cogger, Victoria C. and Xie, Wei-Fen and Tacke, Frank and Gracia-Sancho, Jordi},
  title        = {In Vitro Models for the Study of Liver Biology and Diseases: Advances and Limitations},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2023},
  doi          = {10.1016/j.jcmgh.2022.11.008},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {559--571},
  publisher    = {Elsevier},
  reportid     = {RWTH-2025-04047},
  url          = {https://publications.rwth-aachen.de/record/1010363},
  volume       = {15},
}

@article{Kelley:1030370,
  author       = {Kelley, Robin Kate and Ueno, Makoto and Yoo, Changhoon and Finn, Richard S. and Furuse, Junji and Ren, Zhenggang and Yau, Thomas and Klümpen, Heinz-Josef and Chan, Stephen L. and Ozaka, Masato and Verslype, Chris and Bouattour, Mohamed and Park, Joon Oh and Barajas, Olga and Pelzer, Uwe and Valle, Juan W. and Yu, Li and Malhotra, Usha and Siegel, Abby B. and Edeline, Julien and Vogel, Arndt and Akce, Mehmet and Ales Diaz, Inmaculada and Alves, Gustavo and Anand, Sumitra and Arslan, Cagatay and Asselah, Jamil and Assenat, Eric and Aubin, Francine and Bai, Li-Yuan and Bai, Yuxian and Barajas, Olga and Bates, Susan and Begbie, Stephen and Ben-Aharon, Irit and Beri, Nina and Berres, Marie-Luise and Blanc, Jean-Frederic and Borbath, Ivan and Bordonaro, Robert and Bouattour, Mohamed and Brandi, Giovanni and Burgoyne, Adam and Butthongkomvong, Kritiya and Camandaroba, Marcos and Cao, Ke and Carballido, Marcela and Chan, Stephan Lam and Chen, Jen-Shi and Chen, Ming-Huang and Chen, Xiaoming and Cheng, Ashley and Chiu, Tai-Jan and Choi, Hye Jin and Chon, Hong Jae and Collignon, Joelle and Cubillo Gracian, Antonio and Davis, Sarah and de Carvalho, Ricardo Saraiva and de Groot, D. J. A. and Demols, Anne and De Vos, Judith and Diab, Maria and Easaw, Jacob and Eatock, Martin and Edeline, Julien and Elias, Rawad and Eskens, Fredericus and Falcone, Alfredo and Fernandez, Plinio and Finn, Richard and Franke, Fabio and Furukawa, Masayuki and Furuse, Junji and Gbolahan, Olumide and Geboes, Karen and Geneser, Keri-Lee and Geng, Zhimin and Geva, Ravit and Gillmore, Roopinder and Goetze, Thorsten and Gou, Hongfeng and Grasselli, Julieta and Gu, Shanzhi and Gumus, Mahmut and Haj Mohammad, Nadia and Hao, Chunyi and Harputluoglu, Hakan and Hatoum, Hassan and Heinemann, Volker and Ho, Wang Kwong and Hsu, Chiun and Hubert, Ayala and Hwang, Juneul and Inanc, Mevlude and Iseas, Soledad and Jeyasingam, Vaishnavi and Jimenez Fonseca, Paula and Joubert, Warren and Juengsamarn, Jitlada and Kaen, Diego and Kanai, Masashi and Kasper-Virchow, Stefan and Kazemi, Ghazaleh and Kelleher, Fergal and Kelley, Robin and Kim, Jin Won and Kim, Jong Gwang and Kinupe Abrahao, Ana Beatriz and Klumpen, Heinz and Kochenderfer, Mark and Kose, Fatih and Lam, Ho Ching and Lee, Choong-kun and Lee, Hyun Woo and Lee, Margaret and Lee, Myung Ah and Lee, Wai Man Sarah and Le Sourd, Samuel and Li, Dongliang and Li, Wei and Liang, Houjie and Liang, Tingbo and Lim, Chun Sen and Lingerfelt, Brian and Lopez, Charles and Low, John and Macarulla Mercade, Teresa and Malka, David and Mao, Yimin and Masi, Gianluca and McCune, Steven and McDermott, Ray and McWhirter, Elaine and Mendez, Guillermo and Milella, Michele and Mizuno, Nobumasa and Mizutani, Tomonori and Moniz, Camila and Morales, Luisa and Munoz Martin, Andres Jesús and Nervi, Bruno and Ngamphaiboon, Nuttapong and Oh, Sang Cheul and Oksuzoglu, Berna and Outlaw, Darryl and Ozaka, Masato and Ozguroglu, Mustafa and Ozyilkan, Ozgur and Painemal, Claudio and Pan, Yueyin and Park, Joon Oh and Pelzer, Uwe and Peng, Chuang and Petorin, Caroline and Pezet, Denis and Power, Derek and Qin, Shukui and Ren, Zhenggang and Roohullah, Aflah and Ryu, Hyewon and Salman, Pamela and Sasaki, Mitsuhito and Sasidharan, Rita and Satoh, Taroh and Schulze, Kornelius and Scott-Brown, Martin and Segovia, Ruben and Seufferlein, Thomas and Siena, Salvatore and Sinapi, Isabelle and Smolenschi, Cristina and Song, Tianqiang and Sookprasert, Aumkhae and Soparattanapaisarn, Nopadol and Starling, Naureen and Stein, Stacey and Stemmer, Salomon and Su, Haichuan and Sugimoto, Rie and Suksombooncharoen, Thatthan and Tam, Vincent and Tan, Ai Lian and Tan, Chih Kiang and Tanasanvimon, Suebpong and Tonini, Giuseppe and Tortora, Giampaolo and Tsuji, Akihito and Ueno, Makoto and Uribe, Rodrigo and Venerito, Marino and Verdaguer Mata, Helena and Verslype, Chris and Victorino, Ana Paula and Vogel, Arndt and Wade, James and Waldschmidt, Dirk Thomas and Wang, Lu and Wan Isahk, Wan Zamaniah and Wasan, Harpeet and Weschenfelder, Rui and Wong, Chun Yin and Wong, Yoke Fui and Yalcin, Suayib and Yanez Weber, Patricio and Yang, Xuezhong and Yasui, Hisateru and Yau, Thomas and Yazici, Ozan and Yen, Chia-Jui and Ying, Jieer and Yoo, Changhoon and Yu, Wenchang and Zhao, Haitao},
  title        = {Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer ({KEYNOTE}-966): a randomised, double-blind, placebo-controlled, phase 3 trial},
  journaltitle = {The lancet},
  year         = {2023},
  doi          = {10.1016/S0140-6736(23)00727-4},
  keywords     = {,CRC1382-Project B04},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10391},
  pages        = {1853--1865},
  publisher    = {Elsevier},
  reportid     = {RWTH-2026-02964},
  url          = {https://publications.rwth-aachen.de/record/1030370},
  volume       = {401},
}

@article{Kister:974578,
  author       = {Kister, Bastian and Viehof, Alina and Rolle-Kampczyk, Ulrike and Schwentker, Annika and Treichel, Nicole and Jennings, Susan A. V. and Wirtz, Theresa and Blank, Lars Mathias and Hornef, Mathias W. and von Bergen, Martin and Clavel, Thomas and Küpfer, Lars},
  title        = {A physiologically based model of bile acid metabolism in mice},
  journaltitle = {iScience},
  year         = {2023},
  doi          = {10.1016/j.isci.2023.107922},
  keywords     = {,CRC1382-Project A06,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project A06,CRC1382-Project B01,CRC1382-Project Q02,CRC1382-Project A05,CRC1382-Project A05},
  location     = {Amsterdam and Boston and London and New York and Oxford and Paris and Philadelphia and San Diego and St. Louis},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {107922},
  publisher    = {Elsevier},
  pubmed       = {pmid:37817939},
  reportid     = {RWTH-2023-11446},
  url          = {https://publications.rwth-aachen.de/record/974578},
  volume       = {26},
}

@article{Kohlhepp:957144,
  author       = {Kohlhepp, Marlene Sophia and Liu, Hanyang and Tacke, Frank and Guillot, Adrien},
  title        = {The contradictory roles of macrophages in non-alcoholic fatty liver disease and primary liver cancer—Challenges and opportunities},
  journaltitle = {Frontiers in molecular biosciences},
  year         = {2023},
  doi          = {10.3389/fmolb.2023.1129831},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1129831},
  publisher    = {Frontiers},
  pubmed       = {pmid:36845555},
  reportid     = {RWTH-2023-04604},
  url          = {https://publications.rwth-aachen.de/record/957144},
  volume       = {10},
}

@article{Krieg:860349,
  author       = {Krieg, Sarah and Roderburg, Christoph and Krieg, Andreas and Lüdde, Tom and Loosen, Sven H. and Kostev, Karel},
  title        = {The association between body height and cancer: a retrospective analysis of 784,192 outpatients in Germany},
  journaltitle = {Journal of cancer research and clinical oncology},
  year         = {2023},
  doi          = {10.1007/s00432-022-04335-0},
  keywords     = {,CRC1382-Project A01},
  location     = {Berlin},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {4275--4282},
  publisher    = {Springer},
  pubmed       = {pmid:36066621},
  reportid     = {RWTH-2022-11343},
  url          = {https://publications.rwth-aachen.de/record/860349},
  volume       = {149},
}

@article{Lan:968282,
  author       = {Lan, Tian and Guillot, Adrien and Tacke, Frank},
  title        = {Somatic mutant clone screening: scan for novel {NASH} target genes in mouse liver},
  journaltitle = {Signal transduction and targeted therapy},
  year         = {2023},
  doi          = {10.1038/s41392-023-01572-8},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {319},
  publisher    = {Macmillan Publishers, part of Springer Nature},
  pubmed       = {pmid:37620333},
  reportid     = {RWTH-2023-08553},
  url          = {https://publications.rwth-aachen.de/record/968282},
  volume       = {8},
}

@article{Laschtowitz:1010365,
  author       = {Laschtowitz, Alena and Lambrecht, Joeri and Puengel, Tobias and Tacke, Frank and Mohr, Raphael},
  title        = {Serum {CXCL}5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression},
  journaltitle = {International journal of molecular sciences},
  year         = {2023},
  doi          = {10.3390/ijms24065295},
  keywords     = {,CRC1382-Project B05},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {5295},
  publisher    = {Molecular Diversity Preservation International},
  reportid     = {RWTH-2025-04049},
  url          = {https://publications.rwth-aachen.de/record/1010365},
  volume       = {24},
}

@article{Loosen:860342,
  author       = {Loosen, Sven H. and Schöler, David and Luedde, Mark and Eschrich, Johannes and Lüdde, Tom and Kostev, Karel and Roderburg, Christoph},
  title        = {Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany},
  journaltitle = {Journal of cancer research and clinical oncology},
  year         = {2023},
  doi          = {10.1007/s00432-022-04198-5},
  keywords     = {,CRC1382-Project A01},
  location     = {Berlin},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {3081--3087},
  publisher    = {Springer},
  pubmed       = {pmid:35867204},
  reportid     = {RWTH-2022-11337},
  url          = {https://publications.rwth-aachen.de/record/860342},
  volume       = {149},
}

@article{Ncube:982722,
  author       = {Ncube, Audrey and Bewersdorf, Lisa and Spitzhorn, Lucas-Sebastian and Loerch, Christiane and Bohndorf, Martina and Graffmann, Nina and May, Lea and Amzou, Samira and Fromme, Malin and Wruck, Wasco and Strnad, Pavel and Adjaye, James},
  title        = {Generation of two Alpha-I antitrypsin deficiency patient-derived induced pluripotent stem cell lines {ISRM}-{AATD}-i{PSC}-1 ({HHUUKD}i011-A) and {ISRM}-{AATD}-i{PSC}-2 ({HHUUKD}i012-A)},
  journaltitle = {Stem cell research},
  year         = {2023},
  doi          = {10.1016/j.scr.2023.103171},
  keywords     = {,CRC1382-Project A03},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {[1]--5},
  publisher    = {Elsevier},
  pubmed       = {pmid:37506509},
  reportid     = {RWTH-CONV-252802},
  url          = {https://publications.rwth-aachen.de/record/982722},
  volume       = {71},
}

@article{Otto:960308,
  author       = {Otto, Carlos Constantin and Wang, Guanwu and Mantas, Anna and Heise, Daniel and Bruners, Philipp and Lang, Sven and Ulmer, Tom Florian and Neumann, Ulf Peter and Heij, Lara Rosaline and Bednarsch, Jan},
  title        = {Time to surgery is not an oncological risk factor in {HCC} patients undergoing liver resection},
  journaltitle = {Langenbeck's archives of surgery},
  year         = {2023},
  doi          = {10.1007/s00423-023-02922-4},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {187},
  publisher    = {Springer},
  pubmed       = {pmid:37160788},
  reportid     = {RWTH-2023-06163},
  url          = {https://publications.rwth-aachen.de/record/960308},
  volume       = {408},
}

@article{Otto:967877,
  author       = {Otto, Julia and Verwaayen, Anna and Penners, Christian and Hundertmark, Jana and Lin, Cheng and Kallen, Carina and Paffen, Daniela and Otto, Tobias and Berger, Hilmar and Tacke, Frank and Weiskirchen, Ralf and Nevzorova, Yulia A. and Bartneck, Matthias and Trautwein, Christian and Sonntag, Roland and Liedtke, Christian},
  title        = {Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice},
  journaltitle = {Cell death \& disease},
  year         = {2023},
  doi          = {10.1038/s41419-023-06077-4},
  keywords     = {,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {549},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:37620309},
  reportid     = {RWTH-2023-08294},
  url          = {https://publications.rwth-aachen.de/record/967877},
  volume       = {14},
}

@article{zdirik:1010367,
  author       = {Özdirik, Burcin and Scherf, Maria and Brumercek, Ana and Nicklaus, Jule M. and Kruis, Tassilo and Haber, Philipp K. and Pratschke, Johann and Tacke, Frank and Sigal, Michael},
  title        = {Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival},
  journaltitle = {Hepatology communications},
  year         = {2023},
  doi          = {10.1097/HC9.0000000000000156},
  keywords     = {,CRC1382-Project B05},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {e0156},
  publisher    = {Wolters Kluwer Health},
  reportid     = {RWTH-2025-04050},
  url          = {https://publications.rwth-aachen.de/record/1010367},
  volume       = {7},
}

@article{Pabst:960187,
  author       = {Pabst, Oliver and Hornef, Mathias W. and Schaap, Frank G. and Cerovic, Vuk and Clavel, Thomas and Bruns, Tony},
  title        = {Gut–liver axis: barriers and functional circuits},
  journaltitle = {Nature reviews / Gastroenterology \& hepatology},
  year         = {2023},
  doi          = {10.1038/s41575-023-00771-6},
  keywords     = {,CRC1382-Project B07,CRC1382-Project B03,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project B06,CRC1382-Project Q04,CRC1382-Project A07},
  location     = {Basingstoke},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {447--461},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:37085614},
  reportid     = {RWTH-2023-06079},
  url          = {https://publications.rwth-aachen.de/record/960187},
  volume       = {20},
}

@article{Pabst:962138,
  author       = {Pabst, Oliver and Nowosad, Carla R.},
  title        = {B cells and the intestinal microbiome in time, space and place},
  journaltitle = {Seminars in immunology},
  year         = {2023},
  doi          = {10.1016/j.smim.2023.101806},
  keywords     = {,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {101806},
  publisher    = {Academic Press},
  pubmed       = {pmid:37473559},
  reportid     = {RWTH-2023-07211},
  url          = {https://publications.rwth-aachen.de/record/962138},
  volume       = {69},
}

@article{Puengel:1010370,
  author       = {Puengel, Tobias and Tacke, Frank},
  title        = {Efruxifermin, an investigational treatment for fibrotic or cirrhotic nonalcoholic steatohepatitis ({NASH})},
  journaltitle = {Expert opinion on investigational drugs},
  year         = {2023},
  doi          = {10.1080/13543784.2023.2230115},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {451--461},
  publisher    = {Routledge, Taylor \& Francis},
  reportid     = {RWTH-2025-04052},
  url          = {https://publications.rwth-aachen.de/record/1010370},
  volume       = {32},
}

@article{Queck:889195,
  author       = {Queck, Alexander and Schwierz, Louise and Gu, Wenyi and Ferstl, Philip G. and Jansen, Christian and Uschner, Frank E. and Praktiknjo, Michael and Chang, Johannes and Brol, Maximilian J. and Schepis, Filippo and Merli, Manuela and Strassburg, Christian P. and Lehmann, Jennifer and Meyer, Carsten and Trebicka, Jonel},
  title        = {Targeted decrease of portal hepatic pressure gradient improves ascites control after {TIPS}},
  journaltitle = {Hepatology},
  year         = {2023},
  doi          = {10.1002/hep.32676},
  keywords     = {,CRC1382-Project A09},
  location     = {New York and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {466--475},
  publisher    = {Wiley Interscience},
  pubmed       = {pmid:35869810},
  reportid     = {RWTH-2023-01016},
  url          = {https://publications.rwth-aachen.de/record/889195},
  volume       = {77},
}

@article{Ramadori:968008,
  author       = {Ramadori, Pierluigi and Woitok, Marius Maximilian and Estévez-Vázquez, Olga and Benedé-Ubieto, Raquel and Leal-Lassalle, Hector and Lamas-Paz, Arantza and Guo, Feifei and Fabre, Jeanne and Otto, Julia and Verwaayen, Anna and Reißing, Johanna and Bruns, Tony and Erschfeld, Stephanie and Haas, Ute and Paffen, Daniela and Nelson, Leonard J. and Vaquero, Javier and Bañares, Rafael and Trautwein, Christian and Cubero, Francisco Javier and Liedtke, Christian and Nevzorova, Yulia A.},
  title        = {Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease},
  journaltitle = {Biochimica et biophysica acta / Molecular basis of disease},
  year         = {2023},
  doi          = {10.1016/j.bbadis.2023.166646},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {166646},
  publisher    = {Elsevier},
  pubmed       = {pmid:36736843},
  reportid     = {RWTH-2023-08386},
  url          = {https://publications.rwth-aachen.de/record/968008},
  volume       = {1869},
}

@article{Rezvani:1010371,
  author       = {Rezvani, Milad and Vallier, Ludovic and Guillot, Adrien},
  title        = {Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and Limitations},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2023},
  doi          = {10.1016/j.jcmgh.2023.01.014},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {1135--1145},
  publisher    = {Elsevier},
  reportid     = {RWTH-2025-04053},
  url          = {https://publications.rwth-aachen.de/record/1010371},
  volume       = {15},
}

@article{Roderburg:860352,
  author       = {Roderburg, Christoph and Loosen, Sven H. and Joerdens, Markus S. and Demir, Münevver and Lüdde, Tom and Kostev, Karel},
  title        = {Antibiotic therapy is associated with an increased incidence of cancer},
  journaltitle = {Journal of cancer research and clinical oncology},
  year         = {2023},
  doi          = {10.1007/s00432-022-03998-z},
  keywords     = {,CRC1382-Project A01},
  location     = {Berlin and Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {1285--1293},
  publisher    = {Springer},
  pubmed       = {pmid:35441344},
  reportid     = {RWTH-2022-11346},
  url          = {https://publications.rwth-aachen.de/record/860352},
  volume       = {149},
}

@article{Ruiz:960928,
  author       = {Ruiz, Mathias and Lacaille, Florence and Schrader, Christina and Pons, Monica and Socha, Piotr and Krag, Aleksander and Sturm, Ekkehard and Bouchecareilh, Marion and Strnad, Pavel},
  title        = {Pediatric and Adult Liver Disease in Alpha-1 Antitrypsin Deficiency},
  journaltitle = {Seminars in liver disease},
  year         = {2023},
  doi          = {10.1055/a-2122-7674},
  keywords     = {,CRC1382-Project A03},
  location     = {Stuttgart and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {258--2666},
  publisher    = {Thieme},
  pubmed       = {pmid:37402396},
  reportid     = {RWTH-2023-06519},
  url          = {https://publications.rwth-aachen.de/record/960928},
  volume       = {43},
}

@article{Schraven:976458,
  author       = {Schraven, Sarah and Brück, Ramona and Rosenhain, Stefanie and Lemainque, Teresa and Heines, David and Noormohammadian, Hormoz and Pabst, Oliver and Lederle, Wiltrud and Gremse, Felix and Kießling, Fabian},
  title        = {{CT}- and {MRI}-Aided Fluorescence Tomography Reconstructions for Biodistribution Analysis},
  journaltitle = {Investigative radiology},
  year         = {2023},
  doi          = {10.1097/RLI.0000000000001052},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project B06,CRC1382-Project B06,CRC1382-Project Q04,CRC1382-Project Q01},
  location     = {Philadelphia, Pa.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {504--512},
  publisher    = {Lippincott Williams \& Wilkins},
  pubmed       = {pmid:38038691},
  reportid     = {RWTH-2024-00249},
  url          = {https://publications.rwth-aachen.de/record/976458},
  volume       = {59},
}

@article{Schraven:957383,
  author       = {Schraven, Sarah and Rosenhain, Stefanie and Brueck, Ramona and Wiechmann, Tim Marvin and Pola, Robert and Etrych, Tomáš and Lederle, Wiltrud and Lammers, Twan and Gremse, Felix and Kießling, Fabian},
  title        = {Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake},
  journaltitle = {Nanomedicine},
  year         = {2023},
  doi          = {10.1016/j.nano.2023.102650},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {102650},
  publisher    = {Elsevier},
  pubmed       = {pmid:36623712},
  reportid     = {RWTH-CONV-251429},
  url          = {https://publications.rwth-aachen.de/record/957383},
  volume       = {48},
}

@article{Soppert:860818,
  author       = {Soppert, Josefin and Brandt, Elisa Fabiana and Heussen, Nicole Maria and Barzakova, Emona and Blank, Lars Mathias and Küpfer, Lars and Hornef, Mathias W. and Trebicka, Jonel and Jankowski, Joachim and Berres, Marie-Luise and Noels, Heidi},
  title        = {Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease: a systematic review and meta-analysis},
  journaltitle = {Clinical Gastroenterology and Hepatology},
  year         = {2023},
  doi          = {10.1016/j.cgh.2022.11.030},
  keywords     = {,CRC1382-Project B04,CRC1382-Project A06,CRC1382-Project B04,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project A04,CRC1382-Project A06,CRC1382-Project A04,CRC1382-Project A04,CRC1382-Project A09},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {2746--2758},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:36470528},
  reportid     = {RWTH-CONV-249753},
  url          = {https://publications.rwth-aachen.de/record/860818},
  volume       = {21},
}

@article{Strnad:982720,
  author       = {Strnad, Pavel and San Martin, Javier},
  title        = {{RNA}i therapeutics for diseases involving protein aggregation: fazirsiran for alpha-1 antitrypsin deficiency-associated liver disease},
  journaltitle = {Expert opinion on investigational drugs},
  year         = {2023},
  doi          = {10.1080/13543784.2023.2239707},
  keywords     = {,CRC1382-Project A03},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {571--581},
  pubmed       = {pmid:37470509},
  reportid     = {RWTH-CONV-252800},
  url          = {https://publications.rwth-aachen.de/record/982720},
  volume       = {32},
}

@article{Su:957971,
  author       = {Su, Huan and Haque, Madhuri and Becker, Svea and Edlund, Karolina and Duda, Julia and Wang, Qingbi and Reißing, Johanna and Marschall, Hanns-Ulrich and Candels, Lena Susanna and Mohamed, Mohamed Ramadan Mohamed and Sjöland, Wilhelm and Liao, Lijun and Drexler, Stephan A. and Strowig, Till and Rahnenführer, Jörg and Hengstler, Jan G. and Hatting, Maximilian and Trautwein, Christian},
  title        = {Long‐term hypercaloric diet exacerbates metabolic liver disease in {PNPLA}3 I148M animals},
  journaltitle = {Liver international},
  year         = {2023},
  doi          = {10.1111/liv.15587},
  keywords     = {,CRC1382-Project A08,CRC1382-Project A08,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1699--1713},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:37073116},
  reportid     = {RWTH-2023-05048},
  url          = {https://publications.rwth-aachen.de/record/957971},
  volume       = {43},
}

@article{Tacke:1010372,
  author       = {Tacke, Frank and Puengel, Tobias and Loomba, Rohit and Friedman, Scott L.},
  title        = {An integrated view of anti-inflammatory and antifibrotic targets for the treatment of {NASH}},
  journaltitle = {Journal of hepatology},
  year         = {2023},
  doi          = {10.1016/j.jhep.2023.03.038},
  keywords     = {,CRC1382-Project B05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {552--566},
  publisher    = {Elsevier Science},
  reportid     = {RWTH-2025-04054},
  url          = {https://publications.rwth-aachen.de/record/1010372},
  volume       = {79},
}

@article{Tilg:1010373,
  author       = {Tilg, Herbert and Adolph, Timon E. and Tacke, Frank},
  title        = {Therapeutic modulation of the liver immune microenvironment},
  journaltitle = {Hepatology},
  year         = {2023},
  doi          = {10.1097/HEP.0000000000000386},
  keywords     = {,CRC1382-Project B05},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {1581--1601},
  publisher    = {Wolters Kluwer Health},
  reportid     = {RWTH-2025-04055},
  url          = {https://publications.rwth-aachen.de/record/1010373},
  volume       = {78},
}

@article{Torow:953437,
  author       = {Torow, Natalia and Hand, Timothy W. and Hornef, Mathias W.},
  title        = {Programmed and environmental determinants driving neonatal mucosal immune development},
  journaltitle = {Immunity},
  year         = {2023},
  doi          = {10.1016/j.immuni.2023.02.013},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {[Cambridge, Mass.]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {485--499},
  publisher    = {Cell Press},
  reportid     = {RWTH-2023-02634},
  url          = {https://publications.rwth-aachen.de/record/953437},
  volume       = {56},
}

@article{Torow:958070,
  author       = {Torow, Natalia and Li, Ronghui and Hitch, Thomas C. A. and Mingels, Clemens and Al Bounny, Shahed and van Best, Niels and Stange, Eva-Lena and Simons, Britta and Maié, Tiago and Rüttger, Lennart and Gubbi, Narasimha Murthy Keshava Prasad and Abbott, Darryl Adelaide and Benabid, Adam and Gadermayr, Michael and Runge, Solveig and Treichel, Nicole and Merhof, Dorit and Rosshart, Stephan Patrick and Jehmlich, Nico and Hand, Timothy Wesley and von Bergen, Martin and Heymann, Felix and Pabst, Oliver and Clavel, Thomas and Tacke, Frank and Lelouard, Hugues and Costa, Ivan G. and Hornef, Mathias W.},
  title        = {M cell maturation and c{DC} activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch},
  journaltitle = {Immunity},
  year         = {2023},
  doi          = {10.1016/j.immuni.2023.04.002},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project B06,CRC1382-Project Q04,CRC1382-Project B05,CRC1382-Project Q02,CRC1382-Project A05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {1220--1238,e1--e7},
  publisher    = {Elsevier},
  reportid     = {RWTH-2023-05098},
  url          = {https://publications.rwth-aachen.de/record/958070},
  volume       = {56},
}

@article{Torres:861913,
  author          = {Torres, Sandra and Ortiz, Cristina and Bachtler, Nadine and Gu, Wenyi and Grünewald, Leon D. and Kraus, Nico and Schierwagen, Robert and Hieber, Christoph and Meier, Caroline and Tyc, Olaf and Joseph Brol, Maximilian and Uschner, Frank Erhard and Nijmeijer, Bart and Welsch, Christoph and Berres, Marie-Luise and Garcia-Ruiz, Carmen and Fernandez-Checa, Jose Carlos and Trautwein, Christian and Vogl, Thomas J. and Zeuzem, Stefan and Trebicka, Jonel and Klein, Sabine},
  title           = {Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis},
  journaltitle    = {Hepatology},
  year            = {2023},
  doi             = {10.1002/hep.32746},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B04,CRC1382-Project A09,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A09,CRC1382-Project A09},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {1228--1240},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:35993369},
  reportid        = {RWTH-CONV-249885},
  url             = {https://publications.rwth-aachen.de/record/861913},
  volume          = {77},
}

@article{Trebicka:856871,
  author       = {Trebicka, Jonel and Zarbock, Alexander},
  title        = {Editorial: terlipressin in patients with acute-on-chronic liver failure grade 3—too late?},
  journaltitle = {Alimentary pharmacology \& therapeutics},
  year         = {2023},
  doi          = {10.1111/apt.17244},
  keywords     = {,CRC1382-Project A09},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {177--178},
  publisher    = {Blackwell Science},
  reportid     = {RWTH-2022-11190},
  url          = {https://publications.rwth-aachen.de/record/856871},
  volume       = {57},
}

@article{Volkert:982734,
  author          = {Volkert, Ines and Fromme, Malin and Schneider, Carolin Victoria and Candels, Lena Susanna and Lindhauer, Cecilia Helen Victoria and Su, Huan and Thorhauge, Katrine and Pons, Monica and Mohamed, Mohamed Ramadan Mohamed and Schneider, Kai Markus and Strnad, Pavel and Trautwein, Christian},
  title           = {Impact of {PNPLA}3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression},
  journaltitle    = {Hepatology},
  year            = {2023},
  doi             = {10.1097/HEP.0000000000000574},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {898--911},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:37625151},
  reportid        = {RWTH-CONV-252815},
  url             = {https://publications.rwth-aachen.de/record/982734},
  volume          = {79},
}

@article{Vonderlin:1010374,
  author       = {Vonderlin, Joscha and Chavakis, Triantafyllos and Sieweke, Michael and Tacke, Frank},
  title        = {The Multifaceted Roles of Macrophages in {NAFLD} Pathogenesis},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2023},
  doi          = {10.1016/j.jcmgh.2023.03.002},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {1311--1324},
  publisher    = {Elsevier},
  reportid     = {RWTH-2025-04056},
  url          = {https://publications.rwth-aachen.de/record/1010374},
  volume       = {15},
}

@thesis{Eswaran:977168,
  author      = {Eswaran, Sreepradha},
  title       = {Role of adhesion molecules and oxidative stress in the development of western-style diet-induced metabolic syndrome and non-alcoholic fatty liver disease},
  year        = {2023},
  abstract    = {Primary non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of the metabolic syndrome (MetS) and is accompanied by meta inflammation, increased oxidative stress, a weakening of the gut barrier, and an imbalance in the intestinal microbiota. The detrimental consequences of NAFLD, including atherosclerosis, type II diabetes, liver fibrosis, liver cirrhosis, and liver cancer, affect more than 600 million adults worldwide. So far, no specific pharmacological interventions are available for the treatment of NAFLD and treatment is focussed on weight loss and anti-diabetic and cholesterol-lowering medications. Immune cell homing is critical for tissue-specific immune responses and unregulated immune cell infiltration has been implicated in different inflammatory diseases. Current literature points to a strong influence of different immune cell populations in worsening NAFLD in a multi-organ-driven manner, involving the adipose tissue, liver and intestine. Understanding the molecular signals utilized by these cell populations and their migratory mechanisms to exit circulation and enter organs will support the development of therapeutic interventions. Immune cell migration is achieved primarily through the selective expression of adhesion molecules and chemokine receptors which allow immune cells to bind their endothelial ligands within the vasculature of effector organs. The aim of this thesis was to better define the contribution of adhesion molecules β7 integrin, Mucosal address in cell adhesion molecule (MAdCAM-1) and L-selectin and the impact of an anti-oxidative stress response to western-style diet (WD)-induced NAFLD in mice. To address these issues (part 1 of this thesis) lymphopenic recombination activation gene-2 (RAG-2)-deficient, RAG-2/β7 integrin-double-deficient and RAG-2/MAdCAM-1-double-deficient mice were compared in steady-state conditions and following different lengths of WD-treatment. In addition, adoptive cell transfers were performed to define the capacity and function of β7 integrin-expressing monocytes. In RAG-2-deficient mice, the absence of β7 integrin protected from WD-induced weight gain and insulin resistance (IR). The improved metabolic phenotype was accompanied by an increase in the relative abundance of the gut-barrier-promoting genus Akkermansia in the intestinal microbiota and by reduced gut epithelial barrier disruption. The absence of the MetS in RAG-2/β7 integrin-double-deficient mice was associated with a reduced colonic infiltration of monocytes. Moreover, β7 integrin-deficient CD115+ monocytes showed a reduced capacity to migrate into the epididymal white adipose tissue (EWAT) and intestine when compared to the respective wild type (WT) monocytes in competitive transfer experiments. In addition, they were comparatively less potent in inducing MetS in C-C chemokine receptor type (CCR-2)-deficient mice. To sum up, these results reveal a previously underappreciated role for β7 integrin in regulating monocyte migration during the development of intestinal low-grade inflammation and MetS in mice. In the second part of the thesis, the combined protective effects of abrogated immune cell migration and upregulated hepatocyte anti-oxidative stress responses for the progression of NAFLD were analysed. This was achieved by using a double-knockout mouse model with a complete L-selectin deletion and an additional hepatocyte-specific Kelch-like ECH-associated protein (Keap)1 deletion (Lsel−/−Keap1Δhepa). Keap1 acts as a negative regulator of nuclear factor erythroid 2-related factor (Nrf-2), the master regulator of the oxidative stress response. L-selectin-deficient mice, as well as Keap-1-deficient mice show an improved outcome of WD-induced NAFLD. By subjecting L-selectin-deficient and Lsel−/−Keap1Δhepa mice to WD-induced NAFLD it turned out that an additional deletion of Keap1 improved features of the MetS like WD-induced weight gain and IR and liver damage in L-selectin-deficient mice but did not completely protect from inflammation and metabolic dysregulation. Overall, these findings point to the importance of adhesion molecule-mediated monocyte migration and oxidative stress responses in driving NAFLD progression, which might be important for the development of new therapies.},
  doi         = {10.18154/RWTH-2024-00623},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project A06,CRC1382-Project B02,CRC1382-Project B02},
  location    = {Aachen},
  namea       = {Blank, Lars Mathias and Wagner, Norbert},
  nameatype   = {supervisor},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2024-00623},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/977168},
}

@thesis{Schwentker:889044,
  author      = {Schwentker, Annika},
  title       = {Enterohepatic cooperation in the postnatal establishment of immune homeostasis},
  year        = {2023},
  abstract    = {Adaption to extra-uterine life after birth represents a challenging task for the host. At this time of high energy demand, nutrition changes from parental to enteral. This requires efficient mucosal absorption of dietary nutrients and might explain the transiently enhanced permeability of the gut mucosa for macromolecules known to cease during what has been termed gut closure. Moreover, the neonatal immune system must adapt to rapid bacterial colonization, especially of the intestinal mucosa, and sudden exposure to microbial stimuli. Gut-absorbed molecules via the portal vein first pass the liver, an organ shifting from a hematopoietic to a metabolic organ in mice only after birth, before entering the systemic circulation. The mechanisms that facilitate efficient nutrient absorption but prevent an inappropriate immune activation by gut-derived microbial stimuli have so far remained ill-defined and are the focus of my work. I could show that oral administration of macromolecular tracers and immune stimuli such as lipopolysaccharide (LPS) to neonate but not adult mice leads to internalization by enterocytes in the distal small intestine and increased serum levels. Since macromolecular internalization by enterocytes was restricted to the distal small intestinal epithelium, characterized in neonates by the presence of supranuclear vacuoles (SNVs) and expression of the endocytic adaptor Disabled homolog 2 (Dab2), I tested the hypothesis of a Dab2-dependent enterocyte internalization and translocation process. Intestinal epithelial cell specific Dab2 knockout mice exhibited reduced protein and fluorescein isothiocyanate (FITC) dextran internalization by enterocytes. However, the translocation of FITC dextran and the internalization and translocation of LPS was unaffected. In contrast, using polarized intestinal epithelial stem cell organoid cultures on transwell filters, I could identify the contribution of the fatty acid translocase CD36, which is highly expressed in the neonatal small intestinal epithelium, for LPS translocation. Furthermore, I could identify increased expression and secretion of the LPS detoxifying enzyme acyloxyacyl hydrolase (AOAH) by the neonatal intestinal epithelium as a potential compensatory mechanism for the elevated LPS exposure. Flow cytometry and quantitative polymerase chain reaction (qPCR) analysis of liver tissue revealed enlarged hepatic immune cell populations in the neonatal liver and enhanced transcriptional activation in neonate but not adult mice upon oral LPS administration. Hepatic cytokine expression was influenced by oral supplementation of the LPS antitoxin Pep19-2.5, altered myeloid differentiation primary response 88 (MyD88) signaling or feeding. Together, my results highlight the complexity of intestinal macromolecular transport during early life, identify a pathway of LPS translocation and characterize a potential compensatory mechanism to prevent inappropriate immune activation to gut-derived LPS. Furthermore, my work helps to explain the previously described immune stimulation during early life and provides the basis for future studies on the long-term consequences for immune homeostasis.},
  doi         = {10.18154/RWTH-2023-00928},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project A06,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project B01},
  location    = {Aachen},
  namea       = {Hornef, Mathias W. and Pabst, Oliver and Blank, Lars Mathias},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen,Diagramme},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2023-00928},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/889044},
}

@article{AbuJhaisha:981990,
  author          = {Abu Jhaisha, Samira and Hohlstein, Philipp and Yagmur, Eray and Köller, Vera and Pollmanns, Maike and Adams, Jule K. and Wirtz, Theresa and Brozat, Jonathan Frederik and Bündgens, Lukas and Hamesch, Karim and Weiskirchen, Ralf and Tacke, Frank and Trautwein, Christian and Koch, Alexander},
  title           = {Soluble Semaphorin 4D Serum Concentrations Are Elevated in Critically Ill Patients with Liver Cirrhosis and Correlate with Aminotransferases},
  journaltitle    = {Diagnostics},
  year            = {2024},
  doi             = {10.3390/diagnostics14040370},
  journalsubtitle = {Open access journal},
  keywords        = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Basel},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {4},
  pages           = {370},
  publisher       = {MDPI},
  pubmed          = {pmid:38396409},
  reportid        = {RWTH-CONV-252066},
  url             = {https://publications.rwth-aachen.de/record/981990},
  volume          = {14},
}

@article{Ay:1007169,
  author       = {Ay, Ümran and Leníček, Martin and Haider, Raphael S. and Classen, Arno and van Eijk, Hans and Koelfat, Kiran V. K. and van der Kroft, Gregory and Neumann, Ulf Peter and Hoffmann, Carsten and Bolm, Carsten and Olde Damink, Steven W. M. and Schaap, Frank G.},
  title        = {Microbially conjugated bile salts found in human bile activate the bile salt receptors {TGR}5 and {FXR}},
  journaltitle = {Hepatology communications},
  year         = {2024},
  doi          = {10.1097/HC9.0000000000000383},
  keywords     = {,CRC1382-Project A07,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A07,CRC1382-Project A07},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {e0383},
  publisher    = {Wolters Kluwer Health},
  pubmed       = {pmid:38517202},
  reportid     = {RWTH-CONV-253523},
  url          = {https://publications.rwth-aachen.de/record/1007169},
  volume       = {8},
}

@article{Bagarolo:988173,
  author       = {Bagarolo, Giulia Ilaria and Bhargava, Shruti and Schierwagen, Robert and Gu, Wenyi and Jankowski, Vera and Soppert, Josefin and Barzakova, Emona and Cascone, Federica and Tyc, Olaf and Kuhl, Christiane K. and Noels, Heidi and Trebicka, Jonel and Jankowski, Joachim},
  title        = {Alterations of the peptidomic composition of peripheral plasma after portal hypertension correction by transjugular intrahepatic portosystemic shunt},
  journaltitle = {npj gut and liver},
  year         = {2024},
  doi          = {10.1038/s44355-024-00001-z},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04,CRC1382-Project A04,CRC1382-Project A09,CRC1382-Project A04,CRC1382-Project A09,CRC1382-Project A09},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {2},
  publisher    = {Springer Nature},
  reportid     = {RWTH-2024-06050},
  url          = {https://publications.rwth-aachen.de/record/988173},
  volume       = {1},
}

@article{Bartimoccia:980393,
  author       = {Bartimoccia, Simona and Praktiknjo, Michael and Nocella, Cristina and Schierwagen, Robert and Cammisotto, Vittoria and Jansen, Christian and Cristiano, Luca and Castellani, Valentina and Chang, Johannes and Carnevale, Roberto and Maiucci, Sofia and Uschner, Frank Erhard and Pignatelli, Pasquale and Brol, Maximilian Joseph and Trebicka, Jonel and Violi, Francesco},
  title        = {Association between endotoxemia and blood no in the portal circulation of cirrhotic patients: results of a pilot study},
  journaltitle = {Internal and emergency medicine},
  year         = {2024},
  doi          = {10.1007/s11739-024-03534-6},
  keywords     = {,CRC1382-Project A09,CRC1382-Project A09},
  location     = {Milan},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {713--720},
  publisher    = {Springer Milan},
  reportid     = {RWTH-2024-02233},
  url          = {https://publications.rwth-aachen.de/record/980393},
  volume       = {19},
}

@article{Baskaya:984570,
  author       = {Baskaya, Ferhan and Lemainque, Teresa and Klinkhammer, Barbara M. and Koletnik, Susanne and von Stillfried, Saskia and Talbot, Steven R. and Boor, Peter and Schulz, Volkmar Adolf and Lederle, Wiltrud and Kießling, Fabian},
  title        = {Pathophysiologic Mapping of Chronic Liver Diseases With Longitudinal Multiparametric {MRI} in Animal Models},
  journaltitle = {Investigative radiology},
  year         = {2024},
  doi          = {10.1097/RLI.0000000000001075},
  keywords     = {,CRC1382-Project Q01,CRC1382-Project Q01},
  location     = {Philadelphia, Pa.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {699--710},
  publisher    = {Lippincott Williams \& Wilkins},
  pubmed       = {pmid:38598653},
  reportid     = {RWTH-2024-04127},
  url          = {https://publications.rwth-aachen.de/record/984570},
  volume       = {59},
}

@article{Brozat:990059,
  author       = {Brozat, Jonathan Frederik and Harbalioğlu, Neval and Hohlstein, Philipp and Abu Jhaisha, Samira and Pollmanns, Maike and Adams, Jule K. and Wirtz, Theresa and Hamesch, Karim and Yagmur, Eray and Weiskirchen, Ralf and Tacke, Frank and Trautwein, Christian and Koch, Alexander},
  title        = {Elevated Serum {KIM}-1 in Sepsis Correlates with Kidney Dysfunction and the Severity of Multi-Organ Critical Illness},
  journaltitle = {International journal of molecular sciences},
  year         = {2024},
  doi          = {10.3390/ijms25115819},
  keywords     = {,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {5819},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:38892009},
  reportid     = {RWTH-2024-07108},
  url          = {https://publications.rwth-aachen.de/record/990059},
  volume       = {25},
}

@article{Burra:1010376,
  author       = {Burra, Patrizia and Zanetto, Alberto and Schnabl, Bernd and Reiberger, Thomas and Montano-Loza, Aldo J. and Asselta, Rosanna and Karlsen, Tom Hemming and Tacke, Frank},
  title        = {Hepatic immune regulation and sex disparities},
  journaltitle = {Nature reviews / Gastroenterology \& hepatology},
  year         = {2024},
  doi          = {10.1038/s41575-024-00974-5},
  keywords     = {,CRC1382-Project B05},
  location     = {Basingstoke},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {869--884},
  publisher    = {Nature Publishing Group},
  pubmed       = {pmid:39237606},
  reportid     = {RWTH-2025-04058},
  url          = {https://publications.rwth-aachen.de/record/1010376},
  volume       = {21},
}

@article{Cerovic:993712,
  author       = {Cerovic, Vuk and Pabst, Oliver and Mowat, Allan McI},
  title        = {The renaissance of oral tolerance: merging tradition and new insights},
  journaltitle = {Nature reviews / Immunology},
  year         = {2024},
  doi          = {10.1038/s41577-024-01077-7},
  keywords     = {,CRC1382-Project B03,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {42--56},
  publisher    = {Nature Publ. Group},
  reportid     = {RWTH-2024-08938},
  url          = {https://publications.rwth-aachen.de/record/993712},
  volume       = {25},
}

@article{Chen:1010377,
  author       = {Chen, Shuai and Zeng, Qinghe and Cai, Xiurong and Xue, Jiaming and Yin, Guo and Song, Peng and Tang, Liming and Klein, Christophe and Tacke, Frank and Guillot, Adrien and Liu, Hanyang},
  title        = {Multiomics analyses decipher intricate changes in the cellular and metabolic landscape of steatotic livers upon dietary restriction and sleeve gastrectomy},
  journaltitle = {International journal of biological sciences},
  year         = {2024},
  doi          = {10.7150/ijbs.98362},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Lake Haven, N.S.W. and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {4438--4457},
  publisher    = {Ivyspring International Publ.},
  pubmed       = {pmid:39247824},
  reportid     = {RWTH-2025-04059},
  url          = {https://publications.rwth-aachen.de/record/1010377},
  volume       = {20},
}

@article{Dai:992092,
  author       = {Dai, Yusang and Junho, Carolina Victoria Cruz and Schieren, Luisa and Wollenhaupt, Julia and Sluimer, Judith C. and van der Vorst, Emiel Petrus Carla and Noels, Heidi},
  title        = {Cellular metabolism changes in atherosclerosis and the impact of comorbidities},
  journaltitle = {Frontiers in cell and developmental biology},
  year         = {2024},
  doi          = {10.3389/fcell.2024.1446964},
  keywords     = {,CRC1382-Project A04},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1446964},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:39188527},
  reportid     = {RWTH-2024-08002},
  url          = {https://publications.rwth-aachen.de/record/992092},
  volume       = {12},
}

@article{Diab:1012466,
  author    = {Diab, Nour and Stange, Eva-Lena and Huei, Yong Chiun and Deiwick, Jörg and Vucur, Mihael and Lüdde, Tom and Hensel, Michael and Torow, Natalia and Zhang, Kaiyi and Hornef, Mathias W.},
  title     = {Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB},
  year      = {2024},
  doi       = {10.1101/2024.09.02.610793},
  keywords  = {,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project A01},
  location  = {Cold Spring Harbor},
  note      = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages     = {31 Seiten},
  publisher = {Cold Spring Harbor Laboratory, NY},
  reportid  = {RWTH-2025-05008},
  url       = {https://publications.rwth-aachen.de/record/1012466},
}

@article{Fromme:985619,
  author       = {Fromme, Malin and Hamesch, Karim and Schneider, Carolin Victoria and Mandorfer, Mattias and Pons, Monica and Thorhauge, Katrine H. and Pereira, Vitor and Sperl, Jan and Frankova, Sona and Reichert, Matthias C. and Benini, Federica and Burbaum, Barbara Constanze and Kleinjans, Moritz and Amzou, Samira and Rademacher, Laura and Bewersdorf, Lisa and Verbeek, Jef and Nevens, Frederik and Genesca, Joan and Miravitlles, Marc and Nuñez, Alexa and Schaefer, Benedikt and Zoller, Heinz and Janciauskiene, Sabina and Waern, Johan and Oliveira, António and Maia, Luís and Simões, Carolina and Mahadeva, Ravi and Fraughen, Daniel D. and Trauner, Michael and Krag, Aleksander and Lammert, Frank and Bals, Robert and Gaisa, Nadine and Aigner, Elmar and Griffiths, William J. and Denk, Helmut and Teumer, Alexander and McElvaney, Noel G. and Turner, Alice M. and Trautwein, Christian and Strnad, Pavel},
  title        = {Alpha-1 Antitrypsin Augmentation and the Liver Phenotype of Adults With Alpha-1 Antitrypsin Deficiency (Genotype Pi∗{ZZ})},
  journaltitle = {Clinical gastroenterology and hepatology},
  year         = {2024},
  doi          = {10.1016/j.cgh.2023.08.038},
  keywords     = {,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {283--294.e5},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:37716616},
  reportid     = {RWTH-2024-04692},
  url          = {https://publications.rwth-aachen.de/record/985619},
  volume       = {22},
}

@article{Fromme:991158,
  author       = {Fromme, Malin and Schneider, Carolin Victoria and Guldiken, Nurdan and Amzou, Samira and Luo, Yizhao and Pons, Monica and Genesca, Joan and Miravitlles, Marc and Thorhauge, Katrine H. and Mandorfer, Mattias and Waern, Johan and Schneider, Kai Markus and Sperl, Jan and Frankova, Sona and Bartel, Marc and Zimmer, Holger and Zorn, Markus and Krag, Aleksander and Turner, Alice and Trautwein, Christian and Strnad, Pavel},
  title        = {Alcohol consumption and liver phenotype of individuals with alpha‐1 antitrypsin deficiency},
  journaltitle = {Liver international},
  year         = {2024},
  doi          = {10.1111/liv.16044},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A03,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {2660--2671},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:39031304},
  reportid     = {RWTH-2024-07725},
  url          = {https://publications.rwth-aachen.de/record/991158},
  volume       = {44},
}

@article{Fu:985618,
  author       = {Fu, Lei and Guldiken, Nurdan and Remih, Katharina and Karl, Anna Sophie and Preisinger, Christian and Strnad, Pavel},
  title        = {Serum/Plasma Proteome in Non-Malignant Liver Disease},
  journaltitle = {International journal of molecular sciences},
  year         = {2024},
  doi          = {10.3390/ijms25042008},
  keywords     = {,CRC1382-Project A03,CRC1382-Project A03},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {2008},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:38396688},
  reportid     = {RWTH-2024-04691},
  url          = {https://publications.rwth-aachen.de/record/985618},
  volume       = {25},
}

@article{Gao:1010378,
  author       = {Gao, Jinhang and Lan, Tian and Kostallari, Enis and Guo, Yangkun and Lai, Enjiang and Guillot, Adrien and Ding, Bisen and Tacke, Frank and Tang, Chengwei and Shah, Vijay H.},
  title        = {Angiocrine signaling in sinusoidal homeostasis and liver diseases},
  journaltitle = {Journal of hepatology},
  year         = {2024},
  doi          = {10.1016/j.jhep.2024.05.014},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {543--561},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:38763358},
  reportid     = {RWTH-2025-04060},
  url          = {https://publications.rwth-aachen.de/record/1010378},
  volume       = {81},
}

@article{Guillot:1010379,
  author       = {Guillot, Adrien and Tacke, Frank},
  title        = {Liver macrophages revisited: The expanding universe of versatile responses in a spatiotemporal context},
  journaltitle = {Hepatology communications},
  year         = {2024},
  doi          = {10.1097/HC9.0000000000000491},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {e0491},
  publisher    = {Wolters Kluwer Health},
  pubmed       = {pmid:38967563},
  reportid     = {RWTH-2025-04061},
  url          = {https://publications.rwth-aachen.de/record/1010379},
  volume       = {8},
}

@article{Hgele:1010380,
  author       = {Hägele, Miriam and Eschrich, Johannes and Ruff, Lukas and Alber, Maximilian and Schallenberg, Simon and Guillot, Adrien and Roderburg, Christoph and Tacke, Frank and Klauschen, Frederick},
  title        = {Leveraging weak complementary labels enhances semantic segmentation of hepatocellular carcinoma and intrahepatic cholangiocarcinoma},
  journaltitle = {Scientific reports},
  year         = {2024},
  doi          = {10.1038/s41598-024-75256-w},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {24988},
  publisher    = {Springer Nature},
  pubmed       = {pmid:39443575},
  reportid     = {RWTH-2025-04062},
  url          = {https://publications.rwth-aachen.de/record/1010380},
  volume       = {14},
}

@article{Harlacher:990132,
  author       = {Harlacher, Eva and Schulte, Corinna and Vondenhoff, Sonja and Schmitt-Kopplin, Philippe and Diederich, Philippe and Hemmers, Christian and Wollenhaupt, Julia and Wollenhaupt, Julia and Veltrop, Rogier J. A. and Biessen, Erik A. L. and Lehrke, Michael and Peters, Björn and Schlieper, Georg Rainer and Kuppe, Christoph and Flöge, Jürgen and Jankowski, Vera and Marx, Nikolaus and Jankowski, Joachim and Noels, Heidi},
  title        = {Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health},
  journaltitle = {Frontiers in Cardiovascular Medicine},
  year         = {2024},
  doi          = {10.3389/fcvm.2024.1346475},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1346475},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:38510194},
  reportid     = {RWTH-2024-07159},
  url          = {https://publications.rwth-aachen.de/record/990132},
  volume       = {11},
}

@article{Hatten:991909,
  author          = {Hatten, Hannes and Colyn, Leticia and Volkert, Ines and Gaßler, Nikolaus and Lammers, Twan and Hofmann, Ute and Hengstler, Jan G. and Schneider, Kai Markus and Trautwein, Christian},
  title           = {Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease},
  journaltitle    = {Biochimica et biophysica acta},
  year            = {2024},
  doi             = {10.1016/j.bbadis.2024.167321},
  journalsubtitle = {BBA / Molecular basis of disease},
  keywords        = {,CRC1382-Project B09,CRC1382-Project A06,CRC1382-Project A08},
  location        = {Amsterdam},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {7},
  pages           = {167321},
  publisher       = {Elsevier},
  pubmed          = {pmid:38943920},
  reportid        = {RWTH-2024-07969},
  url             = {https://publications.rwth-aachen.de/record/991909},
  volume          = {1870},
}

@article{Hitch:988372,
  author    = {Hitch, Thomas C. A. and Masson, Johannes M. and Pauvert, Charlie and Bosch, Johanna and Nüchtern, Selina and Treichel, Nicole and Baloh, Marko and Razavi, Soheila and Afrizal, Afrizal and Kousetzi, Ntana and Aguirre, Andrea M. and Wylensek, David and Coates, Amy and Jennings, Susan A. V. and Panyot, Atscharah and Viehof, Alina and Schmitz, Matthias and Stuhrmann, Maximilian and Deis, Evelyn C. and Bisdorf, Kevin and Chiotelli, Maria D. and Lissin, Artur and Schober, Isabel and Witte, Julius and Cramer, Thorsten and Riedel, Thomas and Wende, Marie and Winter, Katrin A. and Amend, Lena and Riva, Alessandra and Trinh, Stefanie Nhu-Binh and Mitchell, Laura and Hartman, Jonathan and Berry, David and Seitz, Jochen and Bossert, Lukas C. and Grognot, Marianne and Allers, Thorsten and Strowig, Till and Pester, Michael and Abt, Birte and Reimer, Lorenz C. and Overmann, Jörg and Clavel, Thomas},
  title     = {Broad diversity of human gut bacteria accessible via a traceable strain deposition system},
  year      = {2024},
  doi       = {10.1101/2024.06.20.599854},
  keywords  = {,CRC1382-Project Q04,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A10,CRC1382-Project Q02,CRC1382-Project A05},
  location  = {Cold Spring Harbor},
  note      = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages     = {48 Seiten},
  publisher = {Cold Spring Harbor Laboratory, NY},
  reportid  = {RWTH-2024-06142},
  url       = {https://publications.rwth-aachen.de/record/988372},
}

@article{Hitch:991647,
  author       = {Hitch, Thomas C. A. and Wylensek, David and Bisdorf, Kevin and Buhl, Eva Miriam and Treichel, Nicole and Abt, Birte and Overmann, Jörg and Clavel, Thomas},
  title        = {Harmonious naming across nomenclature codes exemplified by the description of bacterial isolates from the mammalian gut},
  journaltitle = {Systematic and applied microbiology},
  year         = {2024},
  doi          = {10.1016/j.syapm.2024.126543},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project Q02},
  location     = {München},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {126543},
  publisher    = {Elsevier},
  pubmed       = {pmid:39163745},
  reportid     = {RWTH-2024-07772},
  url          = {https://publications.rwth-aachen.de/record/991647},
  volume       = {47},
}

@article{Hohlstein:990053,
  author       = {Hohlstein, Philipp and Schumacher, Eileen and Abu Jhaisha, Samira and Adams, Jule K. and Pollmanns, Maike and Schneider, Carolin Victoria and Hamesch, Karim and Horvathova, Katarina and Wirtz, Theresa and Tacke, Frank and Trautwein, Christian and Weiskirchen, Ralf and Koch, Alexander},
  title        = {Soluble Neuropilin-1 Is Elevated in Sepsis and Correlates with Organ Dysfunction and Long-Term Mortality in Critical Illness},
  journaltitle = {International journal of molecular sciences},
  year         = {2024},
  doi          = {10.3390/ijms25105438},
  keywords     = {,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Basel},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {5438},
  publisher    = {Molecular Diversity Preservation International},
  pubmed       = {pmid:38791476},
  reportid     = {RWTH-2024-07102},
  url          = {https://publications.rwth-aachen.de/record/990053},
  volume       = {25},
}

@article{Horn:1010381,
  author       = {Horn, Paul and Tacke, Frank},
  title        = {Metabolic reprogramming in liver fibrosis},
  journaltitle = {Cell metabolism},
  year         = {2024},
  doi          = {10.1016/j.cmet.2024.05.003},
  keywords     = {,CRC1382-Project B05},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {1439--1455},
  publisher    = {Elsevier},
  pubmed       = {pmid:38823393},
  reportid     = {RWTH-2025-04063},
  url          = {https://publications.rwth-aachen.de/record/1010381},
  volume       = {36},
}

@article{Jennings:983114,
  author       = {Jennings, Susan A. V. and Clavel, Thomas},
  title        = {Synthetic Communities of Gut Microbes for Basic Research and Translational Approaches in Animal Health and Nutrition},
  journaltitle = {Annual review of animal biosciences},
  year         = {2024},
  doi          = {10.1146/annurev-animal-021022-025552},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {283--300},
  pubmed       = {pmid:37963399},
  reportid     = {RWTH-CONV-253177},
  url          = {https://publications.rwth-aachen.de/record/983114},
  volume       = {12},
}

@article{Koelfat:1007626,
  author       = {Koelfat, Kiran V. K. and Schaap, Frank G. and van Mierlo, Kim M. C. and Leníček, Martin and Sauer, Ilka and van der Kroft, Gregory and Röth, Anjali Anna Joy and Bednarsch, Jan and Amygdalos, Iakovos and Lurje, Georg and Dewulf, Maxime J. L. and Lang, Sven and Neumann, Ulf Peter and Olde Damink, Steven W. M.},
  title        = {Partial liver resection alters the bile salt-{FGF}19 axis in patients with perihilar cholangiocarcinoma: Implications for liver regeneration},
  journaltitle = {Hepatology communications},
  year         = {2024},
  doi          = {10.1097/HC9.0000000000000445},
  keywords     = {,CRC1382-Project B08,CRC1382-Project A01,CRC1382-Project A06,CRC1382-Project A07,CRC1382-Project A07},
  location     = {[Alphen aan den Rijn]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {e0445},
  publisher    = {Wolters Kluwer Health},
  pubmed       = {pmid:38836805},
  reportid     = {RWTH-CONV-253987},
  url          = {https://publications.rwth-aachen.de/record/1007626},
  volume       = {8},
}

@article{Koop:989638,
  author       = {Koop, Paul-Henry and Schwenzer, Constanze and Clusmann, Jan Niklas and Vell, Mara and Jaeger, Julius and Gui, Wenfang and Trautwein, Christian and Koch, Alexander and Bruns, Tony and Schneider, Carolin Victoria and Schneider, Kai Markus},
  title        = {Comorbidities, mortality and metabolic profile in individuals with primary biliary cholangitis—A Phenome‐Wide‐Association‐Study},
  journaltitle = {Liver international},
  year         = {2024},
  doi          = {10.1111/liv.15945},
  keywords     = {,CRC1382-Project B07,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {2038--2053},
  publisher    = {Wiley-Blackwell},
  reportid     = {RWTH-2024-06905},
  url          = {https://publications.rwth-aachen.de/record/989638},
  volume       = {44},
}

@article{Kumar:1010382,
  author          = {Kumar, Pavitra and Hassan, Mohsin and Tacke, Frank and Engelmann, Cornelius},
  title           = {Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes},
  journaltitle    = {Cellular and molecular life sciences},
  year            = {2024},
  doi             = {10.1007/s00018-024-05230-2},
  journalsubtitle = {(CMLS)},
  keywords        = {,CRC1382-Project B05},
  location        = {Cham (ZG)},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {1},
  pages           = {200},
  publisher       = {Springer International Publishing AG},
  pubmed          = {pmid:38684535},
  reportid        = {RWTH-2025-04064},
  url             = {https://publications.rwth-aachen.de/record/1010382},
  volume          = {81},
}

@article{Lan:1010384,
  author          = {Lan, Tian and Tacke, Frank},
  title           = {Diagnostics and omics technologies for the detection and prediction of metabolic dysfunction-associated steatotic liver disease-related malignancies},
  journaltitle    = {Metabolism},
  year            = {2024},
  doi             = {10.1016/j.metabol.2024.156015},
  journalsubtitle = {Clinical and experimental},
  keywords        = {,CRC1382-Project B05},
  location        = {Orlando, Fla.},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages           = {156015},
  publisher       = {Elsevier},
  pubmed          = {pmid:39216799},
  reportid        = {RWTH-2025-04066},
  url             = {https://publications.rwth-aachen.de/record/1010384},
  volume          = {161},
}

@article{Liu:1022932,
  author          = {Liu, Hanyang and Lefere, Sander and Guillot, Adrien and Zheng, Ming-Hua and Tacke, Frank},
  title           = {Bariatric surgery for metabolic dysfunction-associated steatotic liver disease ({MASLD}): Current knowledge of mechanisms},
  journaltitle    = {Hepatology},
  year            = {2024},
  doi             = {10.1097/HEP.0000000000001417},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages           = {1--17},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:40445858},
  reportid        = {RWTH-2025-10367},
  url             = {https://publications.rwth-aachen.de/record/1022932},
}

@article{Liu:989201,
  author       = {Liu, Hanyang and Yin, Guo and Kohlhepp, Marlene Sophia and Schumacher, Fabian and Hundertmark, Jana and Abdelwahab Hassan, Mohamed I. and Heymann, Felix and Puengel, Tobias and Kleuser, Burkhard and Mosig, Alexander Sandy and Tacke, Frank and Guillot, Adrien},
  title        = {Dissecting Acute Drug-Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver-On-A-Chip Model},
  journaltitle = {Advanced science},
  year         = {2024},
  doi          = {10.1002/advs.202403516},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Weinheim},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {30},
  pages        = {2403516},
  publisher    = {Wiley-VCH},
  pubmed       = {pmid:38868948},
  reportid     = {RWTH-2024-06646},
  url          = {https://publications.rwth-aachen.de/record/989201},
  volume       = {11},
}

@article{Loosen:1007200,
  author       = {Loosen, Sven H. and Benz, Fabian and Mohr, Raphael and Reuken, Philipp A. and Wirtz, Theresa and Junker, Lioba Cornelia and Jansen, Christian and Meyer, Carsten and Praktiknjo, Michael and Wree, Alexander and Reißing, Johanna and Demir, Münevver and Gu, Wenyi and Vucur, Mihael and Schierwagen, Robert and Stallmach, Andreas and Kunstein, Anselm and Bode, Johannes and Trautwein, Christian and Tacke, Frank and Lüdde, Tom and Bruns, Tony and Trebicka, Jonel and Roderburg, Christoph},
  title        = {Soluble urokinase plasminogen activator receptor levels predict survival in patients with portal hypertension undergoing {TIPS}},
  journaltitle = {JHEP Rep},
  year         = {2024},
  doi          = {10.1016/j.jhepr.2024.101054},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A01,CRC1382-Project A09,CRC1382-Project B05,CRC1382-Project A06,CRC1382-Project A08,CRC1382-Project A09},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {101054},
  publisher    = {Elsevier},
  pubmed       = {pmid:38681861},
  reportid     = {RWTH-CONV-253575},
  url          = {https://publications.rwth-aachen.de/record/1007200},
  volume       = {6},
}

@article{Lurje:1010385,
  author       = {Lurje, Isabella and Tacke, Frank},
  title        = {The Interleukin 33–T Helper 2 Cell Axis Promotes Human Liver Fibrosis},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2024},
  doi          = {10.1016/j.jcmgh.2024.01.004},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {657--659},
  publisher    = {Elsevier},
  pubmed       = {pmid:38290698},
  reportid     = {RWTH-2025-04067},
  shortjournal = {CMGH},
  url          = {https://publications.rwth-aachen.de/record/1010385},
  volume       = {17},
}

@article{Myrmel:991648,
  author       = {Myrmel, Lene Secher and Fjære, Even and Han, Mo and Jensen, Benjamin Anderschou Hollbech and Rolle-Kampczyk, Ulrike and Danneskiold-Samsøe, Niels Banhos and Ho, Quang Tri and Smette, Anita and von Bergen, Martin and Xiao, Liang and Kristiansen, Karsten and Madsen, Lise},
  title        = {The Food Sources in Western Diets Modulate Obesity Development, Insulin Sensitivity, and the Plasma and Cecal Metabolome in Mice},
  journaltitle = {Molecular nutrition \& food research},
  year         = {2024},
  doi          = {10.1002/mnfr.202400246},
  keywords     = {,CRC1382-Project A05},
  location     = {Weinheim},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {16},
  pages        = {2400246},
  publisher    = {Wiley-VCH},
  pubmed       = {pmid:39107912},
  reportid     = {RWTH-2024-07773},
  url          = {https://publications.rwth-aachen.de/record/991648},
  volume       = {68},
}

@article{Niemietz:1007542,
  author          = {Niemietz, Patricia Maria and Peiseler, Moritz and Kohlhepp, Marlene and Horn, Paul and Matchett, Kylie and Wang, Yuting and Haas, Leon and Zhang, Tianjiao and Bruneau, Alix and Guillot, Adrien and Berger, Hilmar and Liepelt, Anke and Warzecha, Klaudia Theresa and Demske, Catharina and Möckel, Diana and Lammers, Twan and Henderson, Neil and Heymann, Felix and Tacke, Frank},
  title           = {C-C chemokine receptor type 7 ({CCR}7) regulates hepatic {CD}8+ T cell homeostasis and response to acute liver injury},
  journaltitle    = {Hepatology},
  year            = {2024},
  doi             = {10.1097/HEP.0000000000000757},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {5},
  pages           = {1104--1119},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:38231043},
  reportid        = {RWTH-CONV-253908},
  url             = {https://publications.rwth-aachen.de/record/1007542},
  volume          = {80},
}

@article{Pabst:983078,
  author       = {Pabst, Oliver and Cerovic, Vuk},
  title        = {Interferon-γ sensing by epithelial cells tames gut inflammation},
  journaltitle = {Nature immunology},
  year         = {2024},
  doi          = {10.1038/s41590-023-01705-9},
  keywords     = {,CRC1382-Project B03,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {9--10},
  publisher    = {Springer Nature Limited},
  pubmed       = {pmid:38168963},
  reportid     = {RWTH-CONV-253156},
  url          = {https://publications.rwth-aachen.de/record/983078},
  volume       = {25},
}

@article{Peiseler:1010369,
  author          = {Peiseler, Moritz and Tacke, Frank},
  title           = {Bile duct-associated macrophages enter the spotlight in inflammatory cholestatic liver disease},
  journaltitle    = {Hepatology},
  year            = {2024},
  doi             = {10.1097/HEP.0000000000000576},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {257--260},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:37607726},
  reportid        = {RWTH-2025-04051},
  url             = {https://publications.rwth-aachen.de/record/1010369},
  volume          = {79},
}

@article{Puengel:978242,
  author       = {Puengel, Tobias and Tacke, Frank},
  title        = {Cell type-specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis},
  journaltitle = {Liver international},
  year         = {2024},
  doi          = {10.1111/liv.15783},
  keywords     = {,CRC1382-Project B05},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {275--278},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:38289588},
  reportid     = {RWTH-2024-01155},
  url          = {https://publications.rwth-aachen.de/record/978242},
  volume       = {44},
}

@article{Puengel:1010386,
  author       = {Puengel, Tobias and Tacke, Frank},
  title        = {Pharmacotherapeutic options for metabolic dysfunction-associated steatotic liver disease: where are we today?},
  journaltitle = {Expert opinion on pharmacotherapy},
  year         = {2024},
  doi          = {10.1080/14656566.2024.2374463},
  keywords     = {,CRC1382-Project B05},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {1249--1263},
  publisher    = {Routledge, Taylor \& Francis},
  pubmed       = {pmid:38954663},
  reportid     = {RWTH-2025-04068},
  url          = {https://publications.rwth-aachen.de/record/1010386},
  volume       = {25},
}

@article{Reiing:1007448,
  author       = {Reißing, Johanna and Berres, Marie-Luise and Strnad, Pavel and Wree, Alexander and Inzaugarat, Maria Eugenia and Trautwein, Christian and Bruns, Tony and Zimmermann, Henning Wolfgang},
  title        = {Th2 Cell Activation in Chronic Liver Disease Is Driven by Local {IL}33 and Contributes to {IL}13-Dependent Fibrogenesis},
  journaltitle = {Cellular and Molecular Gastroenterology and Hepatology},
  year         = {2024},
  doi          = {10.1016/j.jcmgh.2023.12.011},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B07,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {517--538},
  pubmed       = {pmid:38158122},
  reportid     = {RWTH-CONV-253808},
  url          = {https://publications.rwth-aachen.de/record/1007448},
  volume       = {17},
}

@article{Rendel:988239,
  author       = {Rendel, Miriam D. and Vitali, Cecilia and Creasy, Kate Townsend and Zhang, David and Scorletti, Eleonora and Huang, Helen and Seeling, Katharina Sophie and Park, Joseph and Hehl, Leonida and Vell, Mara and Conlon, Donna and Hayat, Sikander and Phillips, Michael C. and Schneider, Kai Markus and Rader, Daniel J. and Schneider, Carolin Victoria},
  title        = {The common p.Ile291Val variant of {ERLIN}1 enhances {TM}6{SF}2 function and is associated with protection against {MASLD}},
  journaltitle = {Med},
  year         = {2024},
  doi          = {10.1016/j.medj.2024.04.010},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {963--980.e5},
  publisher    = {Elsevier},
  reportid     = {RWTH-2024-06105},
  url          = {https://publications.rwth-aachen.de/record/988239},
  volume       = {5},
}

@article{RiveraEsteban:1010388,
  author       = {Rivera-Esteban, Jesús and Muñoz-Martínez, Sergio and Higuera, Mónica and Sena, Elena and Bermúdez-Ramos, María and Bañares, Juan and Martínez-Gomez, María and Cusidó, M. Serra and Jiménez-Masip, Alba and Francque, Sven M. and Tacke, Frank and Minguez, Beatriz and Pericàs, Juan M.},
  title        = {Phenotypes of Metabolic Dysfunction–Associated Steatotic Liver Disease–Associated Hepatocellular Carcinoma},
  journaltitle = {Clinical gastroenterology and hepatology},
  year         = {2024},
  doi          = {10.1016/j.cgh.2024.03.028},
  keywords     = {,CRC1382-Project B05},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {9},
  pages        = {1774--1789.e8},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:38604295},
  reportid     = {RWTH-2025-04070},
  url          = {https://publications.rwth-aachen.de/record/1010388},
  volume       = {22},
}

@article{Rooney:989319,
  author       = {Rooney, Michael and Duduskar, Shivalee N. and Ghait, Mohamed and Reißing, Johanna and Stengel, Sven and Reuken, Philipp A. and Quickert, Stefanie and Zipprich, Alexander and Bauer, Michael and Russo, Ashley J. and Rathinam, Vijay A. and Stallmach, Andreas and Rubio, Ignacio and Bruns, Tony},
  title        = {Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release upon infection},
  journaltitle = {Journal of hepatology},
  year         = {2024},
  doi          = {10.1016/j.jhep.2024.06.019},
  keywords     = {,CRC1382-Project B07},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {971--982},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:38936554},
  reportid     = {RWTH-2024-06722},
  url          = {https://publications.rwth-aachen.de/record/989319},
  volume       = {18},
}

@article{Schfer:990592,
  author       = {Schäfer, Raphael and Nicke, Till and Höfener, Henning and Lange, Annkristin and Merhof, Dorit and Feuerhake, Friedrich and Schulz, Volkmar Adolf and Lotz, Johannes and Kießling, Fabian},
  title        = {Overcoming data scarcity in biomedical imaging with a foundational multi-task model},
  journaltitle = {Nature computational science},
  year         = {2024},
  doi          = {10.1038/s43588-024-00662-z},
  keywords     = {,CRC1382-Project Q01},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {495--509},
  publisher    = {Nature Research},
  pubmed       = {pmid:39030386},
  reportid     = {RWTH-2024-07440},
  url          = {https://publications.rwth-aachen.de/record/990592},
  volume       = {4},
}

@article{Schmitz:995971,
  author   = {Schmitz, Matthias and Dimonaco, Nicholas J. and Clavel, Thomas and Hitch, Thomas C. A.},
  title    = {Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut},
  year     = {2024},
  doi      = {10.1101/2024.05.29.596415},
  keywords = {,CRC1382-Project A05,CRC1382-Project Q02},
  note     = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages    = {30 Seiten},
  reportid = {RWTH-2024-10273},
  url      = {https://publications.rwth-aachen.de/record/995971},
}

@article{Schophaus:990682,
  author       = {Schophaus, Simon and Creasy, Kate Townsend and Koop, Paul-Henry and Clusmann, Jan and Jaeger, Julius and Punnuru, Varnitha and Koch, Alexander and Trautwein, Christian and Loomba, Rohit and Lüdde, Tom and Schneider, Kai Markus and Schneider, Carolin Victoria},
  title        = {Machine learning uncovers manganese as a key nutrient associated with reduced risk of steatotic liver disease},
  journaltitle = {Liver international},
  year         = {2024},
  doi          = {10.1111/liv.16055},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A01,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A06,CRC1382-Project A08},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {2807--2821},
  publisher    = {Wiley-Blackwell},
  reportid     = {RWTH-2024-07496},
  url          = {https://publications.rwth-aachen.de/record/990682},
  volume       = {44},
}

@article{SchulzeSpte:1005836,
  author       = {Schulze-Späte, Ulrike and Wurschi, Ludwig and van der Vorst, Emiel Petrus Carla and Hölzle, Frank and Craveiro, Rogerio B. and Wolf, Michael and Noels, Heidi},
  title        = {Crosstalk between periodontitis and cardiovascular risk},
  journaltitle = {Frontiers in immunology},
  year         = {2024},
  doi          = {10.3389/fimmu.2024.1469077},
  keywords     = {,CRC1382-Project A04},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1469077},
  publisher    = {Frontiers Media},
  pubmed       = {pmid:39717783},
  reportid     = {RWTH-2025-02035},
  url          = {https://publications.rwth-aachen.de/record/1005836},
  volume       = {15},
}

@article{Shevchenko:988763,
  author       = {Shevchenko, Yaroslava and Lurje, Isabella and Tacke, Frank and Hammerich, Linda},
  title        = {Fluorochrome‐dependent specific changes in spectral profiles using different compensation beads or primary cells in full spectrum cytometry},
  journaltitle = {Cytometry / Part A},
  year         = {2024},
  doi          = {10.1002/cyto.a.24836},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {458--463},
  publisher    = {Wiley-Liss},
  pubmed       = {pmid:38511720},
  reportid     = {RWTH-2024-06375},
  url          = {https://publications.rwth-aachen.de/record/988763},
  volume       = {105},
}

@article{Toivola:981980,
  author       = {Toivola, Diana M. and Polari, Lauri and Schwerd, Tobias and Schlegel, Nicolas and Strnad, Pavel},
  title        = {The keratin-desmosome scaffold of internal epithelia in health and disease - The plot is thickening},
  journaltitle = {Current opinion in cell biology},
  year         = {2024},
  doi          = {10.1016/j.ceb.2023.102282},
  keywords     = {,CRC1382-Project A03},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {102282},
  publisher    = {Elsevier},
  pubmed       = {pmid:38000362},
  reportid     = {RWTH-CONV-252043},
  url          = {https://publications.rwth-aachen.de/record/981980},
  volume       = {86},
}

@article{Werner:1010390,
  author       = {Werner, Wiebke and Kuzminskaya, Maria and Lurje, Isabella and Tacke, Frank and Hammerich, Linda},
  title        = {Overcoming Resistance to Immune Checkpoint Blockade in Liver Cancer with Combination Therapy: Stronger Together?},
  journaltitle = {Seminars in liver disease},
  year         = {2024},
  doi          = {10.1055/a-2334-8311},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Stuttgart and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {02},
  pages        = {159--179},
  publisher    = {Thieme},
  pubmed       = {pmid:38806159},
  reportid     = {RWTH-2025-04071},
  url          = {https://publications.rwth-aachen.de/record/1010390},
  volume       = {44},
}

@article{Zhang:983109,
  author       = {Zhang, Kaiyi and Repnik, Urska and Diab, Nour and Friske, Daniel and Pütz, Andreas and Bachmann, Alina Zoe and Gubbi, Narasimha Murthy Keshava Prasad and Hensel, Michael and Förstner, Konrad U. and Westermann, Alexander J. and Dupont, Aline and Hornef, Mathias W.},
  title        = {Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host},
  journaltitle = {Journal of experimental medicine},
  year         = {2024},
  doi          = {10.1084/jem.20231237},
  keywords     = {,CRC1382-Project B01,CRC1382-Project Q03},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {e20231237},
  publisher    = {Rockefeller Univ. Press},
  pubmed       = {pmid:38305765},
  reportid     = {RWTH-CONV-253185},
  shortjournal = {JEM},
  url          = {https://publications.rwth-aachen.de/record/983109},
  volume       = {221},
}

@thesis{Kister:986586,
  author      = {Kister, Bastian Karl},
  title       = {Physiologically-based modeling of bile acid metabolism in mice and human},
  year        = {2024},
  abstract    = {Bile acid (BA) metabolism represents a multifaceted system involving a diverse array of primary and secondary, conjugated and unconjugated BAs that engage in constant enterohepatic circulation (EHC). Disruptions in both BA composition and dynamics have been correlated with various ailments. Nonetheless, a comprehensive understanding of the intricate interplay between altered BA metabolism and associated diseases remains elusive. A range of animal models have been harnessed to explore BA metabolism’s implications in human disease. Among these models, mice take a prominent role; however, disparities between this preclinical model and humans regarding BA composition, recycling mechanisms, gut physiology, and energy homeostasis exist. Given the inherent intricacy of BA metabolism and the necessity for robust cross-species extrapolation strategies, computational modeling serves as a tool to unravel the mechanistic foundations of the complex network governing BA metabolism. This work endeavors to construct physiologically-based models of BA metabolism in both murine and human contexts. These models recapitulate the synthesis, hepatic and microbial transformations, systemic distribution, excretion, and EHC of BAs at the whole-body level. The murine models were applied in assessments of sex-related and species-specific differences in BA metabolism, as well as the effects of pathophysiological scenarios like BA malabsorption and compromised intestinal barrier function. Conversely, the human models reproduced inter-individual variations in BA levels reported in literature, but also proposing conceivable mechanisms explaining elevated BA levels observed in patients with liver-related disorders. The models developed in this thesis constitute a robust framework for conducting model-assisted inquiries into BA metabolism within prospective studies. Their potential contributions align with the principles of the ’3Rs’ (Reduction, Refinement, and Replacement) of animal testing and hold potential to advance patient care by enhancing our understanding and prediction of BA-related dynamics in disease.},
  doi         = {10.18154/RWTH-2024-05286},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project A06,CRC1382-Project A06},
  location    = {Aachen},
  namea       = {Blank, Lars Mathias and Küpfer, Lars},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2024-05286},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/986586},
}

@thesis{Verwaayen:1000472,
  author      = {Verwaayen, Anna},
  title       = {Differential role of the cell cycle regulators Cyclin E1 and Cyclin E2 for intestinal homeostasis},
  year        = {2024},
  abstract    = {Destruction of the intestinal epithelium affect gut homeostasis causing not only pathological alterations of the gut, but also of the liver due to their close connection via the gut-liver axis. Therefore, maintenance of the intestinal epithelium and gut homeostasis needs to be precisely regulated and consequently strongly depends on a strictly controlled cell cycle. One critical step during cell cycle progression is the transition into the S-phase of the cell cycle. This process is typically controlled by the Cyclin-dependent kinase 2 (CDK2) and their associated E-type Cyclins Cyclin E1 and E2. The present study aimed to elucidate the so far unknown role of the Cyclin E/CDK2 complex for gut homeostasis. Thereby, the differential role of Cyclin E1 and Cyclin E2 under basal and pathological conditions were investigated. For the analysis under basal conditions, mice deficient for the whole Cyclin E/CDK2 complex (i.e. Ccne1, Ccne2, and Cdk2, referred to as TKO mice) in intestinal epithelial cells (IECs) were generated. Mice only deficient for Cyclin E1 in IECs were chronically exposed to alcohol containing liquid diet for eight weeks. TKO mice at the age of twelve weeks as well as alcohol-treated mice were analysed for intestinal proliferation, gut barrier function, microbiota profiles and liver homeostasis. To investigate the role of Cyclin E1 during colorectal cancer (CRC) and colitis development, mice with constitutive deletion of Cyclin E1 were challenged with the AOM/DSS model to induce CRC as well as with acute DSS model leading to experimental colitis. The study identified three key findings. First, mice lacking Cyclin E2 expression unexpectedly revealed an elevated cell cycle activity in the colon and an enhanced intestinal barrier, which was associated with elevated expression of the tight junction protein ZO-1. Second, Cyclin E1 was shown to be involved in controlling the length of the small intestine both under basal conditions but also after chronic ethanol exposure. Finally, mice with constitutive deletion of Cyclin E1 were protected from severe acute DSS-mediated colitis, which was associated with an improved inflammatory phenotype and an altered microbial composition. In summary, the present study revealed that the Cyclin E/CDK2 complex is general dispensable for the renewal of the intestinal epithelium. However, a differential role of Cyclin E1 and Cyclin E2 for maintenance of gut homeostasis could be demonstrated. While Cyclin E2 is mainly involved in colon homeostasis under basal conditions, Cyclin E1 was identified as important novel factor during elongation of the small intestine. Additionally, this study provided strong evidence for a pro-inflammatory role of Cyclin E1 in acute experimental colitis.},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project Q03},
  location    = {Aachen},
  namea       = {Liedtke, Christian and Hornef, Mathias W. and Spehr, Marc},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {125 Seiten : Illustrationen},
  reportid    = {RWTH-2025-00384},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1000472},
}

@article{Balcar:1019325,
  author       = {Balcar, Lorenz and Fromme, Malin and Kappe, Naomi and Schaefer, Benedikt and Fraňková, Soňa and van Melkebeke, Lukas and Stolk, Jan and Jachs, Mathias and Semmler, Georg and Hofer, Benedikt S. and Tergast, Tammo L. and Rieland, Hannah and Karl, Anna Sophie and Sperl, Jan and Wagner, Martin and Pons, Mònica and Hofer, Harald and Peck-Radosavljevic, Markus and Trauner, Michael and Reiberger, Thomas and Maasoumy, Benjamin and Zoller, Heinz and van Hoek, Bart and Verbeek, Jef and Strnad, Pavel and Mandorfer, Mattias},
  title        = {Severe alpha-1 antitrypsin deficiency is associated with a higher risk of complications after first decompensation than other aetiologies of cirrhosis},
  journaltitle = {JHEP reports},
  year         = {2025},
  doi          = {10.1016/j.jhepr.2025.101398},
  keywords     = {,CRC1382-Project A03},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {101398},
  publisher    = {Elsevier},
  pubmed       = {pmid:40535554},
  reportid     = {RWTH-2025-08336},
  url          = {https://publications.rwth-aachen.de/record/1019325},
  volume       = {7},
}

@article{Benderski:1003271,
  author       = {Benderski, Karina and Schneider, Paul and Kordeves, Panayiotis and Fichter, Michael and Schunke, Jenny and De Lorenzi, Federica and Durak, Feyza and Schrörs, Barbara and Akilli, Özlem and Kießling, Fabian and Bros, Matthias and Diken, Mustafa and Grabbe, Stephan and Schattenberg, Jörn M. and Lammers, Twan and Sofias, Alexandros Marios and Kaps, Leonard},
  title        = {A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing},
  journaltitle = {Pharmacological research},
  year         = {2025},
  doi          = {10.1016/j.phrs.2024.107560},
  keywords     = {,CRC1382-Project Q01},
  location     = {[Amsterdam]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {107560},
  publisher    = {Elsevier},
  pubmed       = {pmid:39730106},
  reportid     = {RWTH-2025-00952},
  url          = {https://publications.rwth-aachen.de/record/1003271},
  volume       = {211},
}

@article{Berger:1026864,
  author       = {Berger, Martin and Kern, Jaana-Sophia and Schulze-Späte, Ulrike and Wolfart, Stefan and Jankowski, Joachim and Wolf, Michael and Marx, Nikolaus and Marx-Schütt, Katharina},
  title        = {Systemic inflammation is a risk factor for oral health: an analysis of data from the {UK} Biobank},
  journaltitle = {Frontiers in immunology},
  year         = {2025},
  doi          = {10.3389/fimmu.2025.1651947},
  keywords     = {,CRC1382-Project A04},
  location     = {Lausanne},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {1651947},
  publisher    = {Frontiers Media},
  reportid     = {RWTH-2026-01020},
  url          = {https://publications.rwth-aachen.de/record/1026864},
  volume       = {16},
}

@article{Bruneau:1003532,
  author       = {Bruneau, Alix and Shevchenko, Yaroslava and Tacke, Frank and Hammerich, Linda},
  title        = {A comprehensive 26‐color immunophenotyping panel to study the role of the gut‐liver axis in chronic liver diseases},
  journaltitle = {Cytometry / Part B},
  year         = {2025},
  doi          = {10.1002/cyto.b.22203},
  keywords     = {,CRC1382-Project B05,CRC1382-Project B05},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {15--22},
  publisher    = {Wiley-Liss},
  pubmed       = {pmid:39252408},
  reportid     = {RWTH-2025-01104},
  url          = {https://publications.rwth-aachen.de/record/1003532},
  volume       = {108},
}

@article{Chen:1015938,
  author       = {Chen, Yazhou and Laevens, Benjamin P. M. and Lemainque, Teresa and Müller-Franzes, Gustav Anton and Seibel, Tobias and Dlugosch, Carola and Clusmann, Jan and Koop, Paul-Henry and Gong, Rongpeng and Liu, Yuanyuan and Jakhar, Niharika and Cao, Feng and Schophaus, Simon and Raju, Thriveni Basavanapura and Raptis, Anastasia Artemis and van Haag, Felix and Joy, Joel and Loomba, Rohit and Valenti, Luca and Kather, Jakob Nikolas and Brinker, Titus J. and Herzog, Moritz and Costa, Ivan G. and Hernando, Diego and Schneider, Kai Markus and Truhn, Daniel and Schneider, Carolin Victoria},
  title        = {Deep Learning Reveals Liver {MRI} Features Associated With {PNPLA}3 I148M in Steatotic Liver Disease},
  journaltitle = {Liver international},
  year         = {2025},
  doi          = {10.1111/liv.70164},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {7},
  pages        = {e70164},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:40478199},
  reportid     = {RWTH-2025-06652},
  url          = {https://publications.rwth-aachen.de/record/1015938},
  volume       = {45},
}

@article{Clark:1019328,
  author       = {Clark, Virginia C. and Price, Mark A. and Russo, Jon and Loomba, Rohit and Turner, Alice M. and Strnad, Pavel},
  title        = {Diagnosis and Monitoring Pathways Using Non-Invasive Tests in Patients With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease: Results From an Expert Delphi Panel},
  journaltitle = {United european gastroenterology journal},
  year         = {2025},
  doi          = {10.1002/ueg2.70009},
  keywords     = {,CRC1382-Project A03},
  location     = {Hoboken, NJ},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1446--1455},
  publisher    = {Wiley},
  pubmed       = {pmid:40072894},
  reportid     = {RWTH-2025-08338},
  url          = {https://publications.rwth-aachen.de/record/1019328},
  volume       = {13},
}

@article{Eswaran:1015383,
  author       = {Eswaran, Sreepradha and Gebert, Laura and Schraven, Sarah and Treichel, Nicole and Ritz, Thomas and Hamm, Sabine and Seeger, Agnes and Kießling, Fabian and Clavel, Thomas and Dreschers, Stephan and Wagner, Norbert and Schippers, Angela},
  title        = {Intercellular adhesion molecule-1 protects against adipose tissue inflammation and insulin resistance but promotes liver disease activity in western-diet fed mice},
  journaltitle = {Scientific reports},
  year         = {2025},
  doi          = {10.1038/s41598-025-11555-0},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B02,CRC1382-Project Q01,CRC1382-Project B02,CRC1382-Project Q02,CRC1382-Project B02},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {25884},
  publisher    = {Springer Nature},
  pubmed       = {pmid:40670579},
  reportid     = {RWTH-2025-06357},
  url          = {https://publications.rwth-aachen.de/record/1015383},
  volume       = {15},
}

@article{Fromme:998261,
  author          = {Fromme, Malin and Payancé, Audrey and Mandorfer, Mattias and Thorhauge, Katrine H. and Pons, Monica and Miravitlles, Marc and Stolk, Jan and van Hoek, Bart and Stirnimann, Guido and Frankova, Sona and Sperl, Jan and Kremer, Andreas E. and Burbaum, Barbara Constanze and Schrader, Christina and Kadioglu, Amine and Walkenhaus, Michelle and Schneider, Carolin Victoria and Klebingat, Fabienne and Balcar, Lorenz and Kappe, Naomi N. and Schaefer, Benedikt and Chorostowska-Wynimko, Joanna and Aigner, Elmar and Gensluckner, Sophie and Striedl, Philipp and Roger, Pauline and Ryan, John and Roche, Suzanne and Vögelin, Marius and Ala, Aftab and Bantel, Heike and Verbeek, Jef and Mariño, Zoe and Praktiknjo, Michael and Gevers, Tom J. G. and Reuken, Philipp A. and Berg, Thomas and George, Jacob and Demir, Münevver and Bruns, Tony and Trautwein, Christian and Zoller, Heinz and Trauner, Michael and Genesca, Joan and Griffiths, William J. and Clark, Virginia and Krag, Aleksander and Turner, Alice M. and McElvaney, Noel G. and Strnad, Pavel},
  title           = {Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗{ZZ} Genotype)},
  journaltitle    = {Gastroenterology},
  year            = {2025},
  doi             = {10.1053/j.gastro.2024.10.010},
  journalsubtitle = {Official publication of the American Gastroenterological Association},
  keywords        = {,CRC1382-Project B07,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03,CRC1382-Project A06,CRC1382-Project A08},
  location        = {New York, NY},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {2},
  pages           = {367--381},
  publisher       = {Elsevier},
  reportid        = {RWTH-2024-11254},
  url             = {https://publications.rwth-aachen.de/record/998261},
  volume          = {168},
}

@article{Haedge:1010306,
  author       = {Haedge, Frederic and Bruns, Tony},
  title        = {Antibiotics in decompensated liver disease – who, when and for how long?},
  journaltitle = {Expert review of gastroenterology \& hepatology},
  year         = {2025},
  doi          = {10.1080/17474124.2025.2464044},
  keywords     = {,CRC1382-Project B07},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {111--130},
  publisher    = {Taylor \& Francis},
  pubmed       = {pmid:39921440},
  reportid     = {RWTH-2025-04002},
  url          = {https://publications.rwth-aachen.de/record/1010306},
  volume       = {19},
}

@article{Haedge:1015851,
  author       = {Haedge, Frederic and Reuken, Philipp A. and Reißing, Johanna and Große, Karsten and Frissen, Mick and El-Hassani, Majda and Aschenbach, Rene and Teichgräber, Ulf and Stallmach, Andreas and Bruns, Tony},
  title        = {Surrogate Markers of Intestinal Permeability, Bacterial Translocation and Gut–Vascular Barrier Damage Across Stages of Cirrhosis},
  journaltitle = {Liver international},
  year         = {2025},
  doi          = {10.1111/liv.70119},
  keywords     = {,CRC1382-Project B07},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {e70119},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:40317887},
  reportid     = {RWTH-2025-06583},
  url          = {https://publications.rwth-aachen.de/record/1015851},
  volume       = {45},
}

@article{Hager:1019760,
  author       = {Hager, Fabian Tobias and Nguyen, Trong-Hieu and Laouina, Asmae and Kopplin, Lydia and Andrusaite, Anna and Jennings, Susan A. V. and Simons, Britta and Leufgen, Andrea and Clavel, Thomas and Milling, Simon and Prinz, Immo and Förster, Reinhold and Stiehl, Thomas Peter and Pabst, Oliver and Cerovic, Vuk},
  title        = {Progressive changes in phenotype, transcriptome and proliferation capacity characterise continued maturation and migration of intestinal c{DC}s in homeostasis},
  journaltitle = {Nature Communications},
  year         = {2025},
  doi          = {10.1038/s41467-025-63559-z},
  keywords     = {,CRC1382-Project B03,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {8204},
  publisher    = {Springer Nature},
  reportid     = {RWTH-2025-08517},
  url          = {https://publications.rwth-aachen.de/record/1019760},
  volume       = {16},
}

@article{Hitch:1011756,
  author       = {Hitch, Thomas C. A. and Masson, Johannes M. and Pauvert, Charlie and Bosch, Johanna and Nüchtern, Selina and Treichel, Nicole and Baloh, Marko and Razavi, Soheila and Afrizal, Afrizal and Kousetzi, Ntana and Aguirre, Andrea M. and Wylensek, David and Coates, Amy and Jennings, Susan A. V. and Panyot, Atscharah and Viehof, Alina and Schmitz, Matthias and Stuhrmann, Maximilian and Deis, Evelyn C. and Bisdorf, Kevin and Chiotelli, Maria D. and Lissin, Artur and Schober, Isabel and Witte, Julius and Cramer, Thorsten and Riedel, Thomas and Wende, Marie and Winter, Katrin A. and Amend, Lena and Riva, Alessandra and Trinh, Stefanie Nhu-Binh and Mitchell, Laura and Hartman, Jonathan Aron and Berry, David and Seitz, Jochen and Bossert, Lukas C. and Grognot, Marianne and Allers, Thorsten and Strowig, Till and Pester, Michael and Abt, Birte and Reimer, Lorenz C. and Overmann, Jörg and Clavel, Thomas},
  title        = {Hi{BC}: a publicly available collection of bacterial strains isolated from the human gut},
  journaltitle = {Nature Communications},
  year         = {2025},
  doi          = {10.1038/s41467-025-59229-9},
  keywords     = {,CRC1382-Project Q04,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A10,CRC1382-Project Q02,CRC1382-Project A05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {4203},
  publisher    = {Springer Nature},
  pubmed       = {pmid:40328737},
  reportid     = {RWTH-2025-04705},
  url          = {https://publications.rwth-aachen.de/record/1011756},
  volume       = {16},
}

@article{IbidapoObe:1023765,
  author       = {Ibidapo-Obe, Oluwatomi and Rooney, Michael D. and Bruns, Tony},
  title        = {Peritoneal immunity in decompensated cirrhosis},
  journaltitle = {Expert review of clinical immunology},
  year         = {2025},
  doi          = {10.1080/1744666X.2025.2565670},
  keywords     = {,CRC1382-Project B07},
  location     = {Abingdon, Oxon},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {10},
  pages        = {1355--1371},
  publisher    = {Taylor \& Francis},
  pubmed       = {pmid:41017754},
  reportid     = {RWTH-2025-10726},
  url          = {https://publications.rwth-aachen.de/record/1023765},
  volume       = {21},
}

@article{IbidapoObe:1010315,
  author       = {Ibidapo-Obe, Oluwatomi and Stengel, Sven and Frissen, Mick and Reißing, Johanna and Große, Karsten and Rooney, Michael and Quickert, Stefanie and Nguyen, Trong-Hieu and Baumgart, Sabine and Leal-Lassalle, Hector and Benedé-Ubieto, Raquel and Nevzorova, Yulia A. and Bruns, Tony},
  title        = {Macrophage-derived {IL}-15 Imprints Peritoneal {TRM}-like {CD}8 T Cells in Cirrhosis and Spontaneous Bacterial Peritonitis},
  journaltitle = {JHEP reports},
  year         = {2025},
  doi          = {10.1016/j.jhepr.2025.101381},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A02},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {101381},
  publisher    = {Elsevier},
  reportid     = {RWTH-2025-04010},
  url          = {https://publications.rwth-aachen.de/record/1010315},
  volume       = {7},
}

@article{Kaesler:1012732,
  author       = {Kaesler, Nadine and Kaushik, Suresh and Frisch, Janina and Ziegler, Susanne and Grommes, Jochen and Gombert, Alexander and Roma, Leticia Prates and Kuppe, Christoph and Jankowski, Joachim and Flöge, Jürgen and de la Puente-Secades, Sofía and Kramann, Rafael and Jankowski, Vera},
  title        = {Vitamin K preserves gamma-glutamyl carboxylase activity against carbamylations in uremia: Implications for vascular calcification and adjunct therapies},
  journaltitle = {Acta physiologica},
  year         = {2025},
  doi          = {10.1111/apha.70040},
  keywords     = {,CRC1382-Project A04},
  location     = {Oxford and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {e70040},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:40202064},
  reportid     = {RWTH-2025-05140},
  url          = {https://publications.rwth-aachen.de/record/1012732},
  volume       = {241},
}

@article{Kappe:1019323,
  author       = {Kappe, Naomi N. and Fromme, Malin and Stolk, Jan and Ferrarotti, Ilaria and Strnad, Pavel and van Hoek, Bart},
  title        = {Performance of enhanced liver fibrosis test and indirect serum fibrosis markers for exclusion of advanced liver fibrosis in alpha-1 antitrypsin deficiency},
  journaltitle = {European journal of internal medicine},
  year         = {2025},
  doi          = {10.1016/j.ejim.2025.07.019},
  keywords     = {,CRC1382-Project A03},
  location     = {Amsterdam and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {106423},
  publisher    = {Elsevier Science},
  pubmed       = {pmid:40713254},
  reportid     = {RWTH-2025-08335},
  url          = {https://publications.rwth-aachen.de/record/1019323},
}

@article{Lauxen:1012225,
  author       = {Lauxen, Jane Sophie and Vondenhoff, Sonja and Junho, Carolina Victoria Cruz and Martin, Philipp and Fleig, Susanne and Schütt, Katharina and Schulze-Späte, Ulrike and Soehnlein, Oliver and Prates-Roma, Leticia and Döring, Yvonne and Baaten, Constance C. F. M. J. and Noels, Heidi},
  title        = {Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta‐Analysis},
  journaltitle = {Acta physiologica},
  year         = {2025},
  doi          = {10.1111/apha.70057},
  keywords     = {,CRC1382-Project A04},
  location     = {Oxford and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {6},
  pages        = {e70057},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:40411205},
  reportid     = {RWTH-2025-04927},
  url          = {https://publications.rwth-aachen.de/record/1012225},
  volume       = {241},
}

@article{Liu:1010392,
  author          = {Liu, Hanyang and Yin, Guo and Franco Leonardi, Bianca and Lan, Tian and Ait Ahmed, Yeni and Berger, Hilmar and Kohlhepp, Marlene Sophia and Amiridze, Natalja and Martagón Calderón, Natalia and Frau, Carla and Vallier, Ludovic and Rezvani, Milad and Tacke, Frank and Guillot, Adrien},
  title           = {Reactive cholangiocyte-derived {ORM}2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming},
  journaltitle    = {Gut},
  year            = {2025},
  doi             = {10.1136/gutjnl-2024-334425},
  journalsubtitle = {An international journal of gastroenterology and hepatology},
  keywords        = {,CRC1382-Project B05,CRC1382-Project B05},
  location        = {London},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {10},
  pages           = {1694--1710},
  publisher       = {BMJ Publishing Group},
  pubmed          = {pmid:40199572},
  reportid        = {RWTH-2025-04073},
  url             = {https://publications.rwth-aachen.de/record/1010392},
  volume          = {74},
}

@article{Loosen:1020579,
  author       = {Loosen, Sven H. and Hansen, Frederik J. and Schatilow, Denis and Wirtz, Theresa and Reuken, Philipp A. and Bode, Johannes and Kunstein, Anselm and Vucur, Mihael and Reißing, Johanna and Flügen, Georg and Castoldi, Mirco and Stallmach, Andreas and Lüdde, Tom and Bruns, Tony and Roderburg, Christoph},
  title        = {Circulating extracellular vesicles predict outcome in patient undergoing transjugular intrahepatic portosystemic shunt ({TIPS}) placement},
  journaltitle = {Scientific reports},
  year         = {2025},
  doi          = {10.1038/s41598-025-20562-0},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A01},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {35015},
  publisher    = {Springer Nature},
  reportid     = {RWTH-2025-09099},
  url          = {https://publications.rwth-aachen.de/record/1020579},
  volume       = {15},
}

@article{Murad:1023766,
  author       = {Murad, Mohamad and Reuken, Philipp A. and Schubert, Kristin and Reißing, Johanna and Ibidapo-Obe, Oluwatomi and Große, Karsten and Frissen, Mick and Haedge, Frederic and El-Hassani, Majda and von Bergen, Martin and Bruns, Tony},
  title        = {The prognostic significance of {HDL}-associated apolipoproteins in ascitic fluid from patients with cirrhosis and spontaneous bacterial peritonitis},
  journaltitle = {Scientific reports},
  year         = {2025},
  doi          = {10.1038/s41598-025-08238-1},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A05},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {25714},
  publisher    = {Springer Nature},
  pubmed       = {pmid:40670426},
  reportid     = {RWTH-2025-10727},
  url          = {https://publications.rwth-aachen.de/record/1023766},
  volume       = {15},
}

@article{Noels:1012226,
  author       = {Noels, Heidi and van der Vorst, Emiel Petrus Carla and Rubin, Sébastien and Emmett, Amber and Marx, Nikolaus and Tomaszewski, Maciej and Jankowski, Joachim},
  title        = {Renal-Cardiac Crosstalk in the Pathogenesis and Progression of Heart Failure},
  journaltitle = {Circulation research},
  year         = {2025},
  doi          = {10.1161/CIRCRESAHA.124.325488},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {11},
  pages        = {1306--1334},
  publisher    = {American Heart Association},
  pubmed       = {pmid:40403103},
  reportid     = {RWTH-2025-04928},
  url          = {https://publications.rwth-aachen.de/record/1012226},
  volume       = {136},
}

@article{zdirik:1010391,
  author       = {Özdirik, Burcin and Berger, Hilmar and Tonetti, Fernanda Raya and Cabré, Noemí and Treichel, Nicole and Clavel, Thomas and Tacke, Frank and Sigal, Michael and Schnabl, Bernd},
  title        = {Faecal Cytolysin is Associated With Worse Survival in Patients With Primary Sclerosing Cholangitis},
  journaltitle = {Liver international},
  year         = {2025},
  doi          = {10.1111/liv.16181},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B05,CRC1382-Project Q02},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {4},
  pages        = {e16181},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:40083245},
  reportid     = {RWTH-2025-04072},
  url          = {https://publications.rwth-aachen.de/record/1010391},
  volume       = {45},
}

@article{Peters:1011653,
  author       = {Peters, Linsey Jeanette Francine and Rakateli, Leonida and Huchzermeier, Rosanna and Bonnin Marquez, Andrea and Maas, Sanne L. and Lin, Cheng and Jans, Alexander and Geng, Yana and Gorter, Alan and Gijbels, Marion and Rensen, Sander and Olinga, Peter and Hendrikx, Tim and Krawczyk, Marcin and Brisbois, Malvina and Jankowski, Joachim and Bidzhekov, Kiril and Weber, Christian and Biessen, Erik A. L. and Shiri-Sverdlov, Ronit and Houben, Tom and Doering, Yvonne and Bartneck, Matthias and van der Vorst, Emiel Petrus Carla},
  title        = {Micro{RNA}-26b protects against {MASH} development in mice and can be efficiently targeted with lipid nanoparticles},
  journaltitle = {eLife},
  year         = {2025},
  doi          = {10.7554/eLife.97165},
  keywords     = {,CRC1382-Project A04},
  location     = {Cambridge},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {RP97165},
  publisher    = {eLife Sciences Publications},
  pubmed       = {pmid:40261813},
  reportid     = {RWTH-2025-04640},
  url          = {https://publications.rwth-aachen.de/record/1011653},
  volume       = {13},
}

@article{delaPuenteSecades:1005964,
  author       = {de la Puente-Secades, Sofía and Mikolajetz, Dustin and Gayrard, Nathalie and Hermann, Juliane and Jankowski, Vera and Bhargava, Shruti and Meyer, Amina and Argilés, Àngel and Saritas, Turgay and van der Vorst, Emiel Petrus Carla and Wu, Zhuojun and Noels, Heidi and Tepel, Martin and Alghamdi, Khaleda and Ward, Donald and Zidek, Walter and Wolf, Michael and Flöge, Jürgen and Schurgers, Leon J. and Orth-Alampour, Setareh and Jankowski, Joachim},
  title        = {Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor},
  journaltitle = {Cardiovascular research},
  year         = {2025},
  doi          = {10.1093/cvr/cvaf016},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {3},
  pages        = {507--521},
  publisher    = {Oxford University Press},
  pubmed       = {pmid:40042167},
  reportid     = {RWTH-2025-02137},
  url          = {https://publications.rwth-aachen.de/record/1005964},
  volume       = {121},
}

@article{Ramachandran:1010387,
  author          = {Ramachandran, Prakash and Tacke, Frank},
  title           = {Exploring the role of macrophages in the pathogenesis of alcohol-associated liver disease},
  journaltitle    = {Hepatology},
  year            = {2025},
  doi             = {10.1097/HEP.0000000000000976},
  journalsubtitle = {Official journal of the American Association for the Study of Liver Diseases},
  keywords        = {,CRC1382-Project B05},
  location        = {[Alphen aan den Rijn]},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {3},
  pages           = {762--764},
  publisher       = {Wolters Kluwer Health},
  pubmed          = {pmid:38889088},
  reportid        = {RWTH-2025-04069},
  url             = {https://publications.rwth-aachen.de/record/1010387},
  volume          = {81},
}

@article{Remih:1008861,
  author       = {Remih, Katharina and Hufnagel, Franziska-Maria and Karl, Anna Sophie and Durkalski-Mauldin, Valerie and Lee, William Martens and Karvellas, Constantine J. and Su, Zemin and Rule, Jody A. and Tomanová, Petra and Krieg, Laura and Karkossa, Isabel and Schubert, Kristin and von Bergen, Martin and Tacke, Frank and Luckhardt, Sonja and Ziegler, Nicole and Kannt, Aimo and Engel, Bastian and Taubert, Richard and Fontana, Robert John and Strnad, Pavel},
  title        = {Serum proteomics of adults with Acute Liver Failure provide mechanistic insights and attractive prognostic biomarkers},
  journaltitle = {JHEP reports},
  year         = {2025},
  doi          = {10.1016/j.jhepr.2025.101338},
  keywords     = {,CRC1382-Project A03,CRC1382-Project B05,CRC1382-Project A05},
  location     = {Amsterdam},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {5},
  pages        = {101338},
  publisher    = {Elsevier},
  pubmed       = {pmid:40242314},
  reportid     = {RWTH-2025-03202},
  url          = {https://publications.rwth-aachen.de/record/1008861},
  volume       = {7},
}

@article{Rosenberger:1019326,
  author          = {Rosenberger, Florian A. and Mädler, Sophia C. and Thorhauge, Katrine Holtz and Steigerwald, Sophia and Fromme, Malin and Lebedev, Mikhail and Weiss, Caroline A. M. and Oeller, Marc and Wahle, Maria and Metousis, Andreas and Zwiebel, Maximilian and Schmacke, Niklas A. and Detlefsen, Sönke and Boor, Peter and Fabián, Ondřej and Fraňková, Soňa and Krag, Aleksander and Strnad, Pavel and Mann, Matthias},
  title           = {Deep Visual Proteomics maps proteotoxicity in a genetic liver disease},
  journaltitle    = {Nature},
  year            = {2025},
  doi             = {10.1038/s41586-025-08885-4},
  journalsubtitle = {International weekly journal of science},
  keywords        = {,CRC1382-Project A03},
  location        = {London and others},
  note            = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number          = {8067},
  pages           = {484--491},
  publisher       = {Nature Publ. Group},
  pubmed          = {pmid:40240610},
  reportid        = {RWTH-2025-08337},
  url             = {https://publications.rwth-aachen.de/record/1019326},
  volume          = {642},
}

@article{Schler:1000099,
  author       = {Schlößer, Stefan and Ullrich, Anna-Lena and Modares, Nastaran Fazel and Schmitz, Matthias and Schöneich, Johannes and Zhang, Kaiyi and Richter, Isabel and Robrahn, Laura Marie and Schraven, Sarah and Nagai, James S. and Haange, Sven-Bastiaan and Jennings, Susan A. V. and Clavel, Thomas and Rolle-Kampczyk, Ulrike and Kießling, Fabian and Costa, Ivan G. and Muncan, Vanesa and Repnik, Urska and von Bergen, Martin and Dupont, Aline and Hornef, Mathias W.},
  title        = {Salmonella infection accelerates postnatal maturation of the intestinal epithelium},
  journaltitle = {Proceedings of the National Academy of Sciences of the United States of America},
  year         = {2025},
  doi          = {10.1073/pnas.2403344122},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project Q01,CRC1382-Project B01,CRC1382-Project A05},
  location     = {Washington, DC},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {e2403344122},
  publisher    = {National Acad. of Sciences},
  pubmed       = {pmid:39793046},
  reportid     = {RWTH-2025-00159},
  url          = {https://publications.rwth-aachen.de/record/1000099},
  volume       = {122},
}

@article{Schmitz:1011733,
  author       = {Schmitz, Matthias and Dimonaco, Nicholas J. and Clavel, Thomas and Hitch, Thomas C. A.},
  title        = {Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut},
  journaltitle = {Nature Communications},
  year         = {2025},
  doi          = {10.1038/s41467-025-58442-w},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {[London]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {3204},
  publisher    = {Springer Nature},
  pubmed       = {pmid:40180917},
  reportid     = {RWTH-2025-04683},
  url          = {https://publications.rwth-aachen.de/record/1011733},
  volume       = {16},
}

@article{Schneider:1013796,
  author       = {Schneider, Carolin Victoria and Gross, Stefan and Balasubramani, Sriram and Tomanová, Petra and Schrader, Christina and Fromme, Malin and Mandorfer, Mattias and Guldiken, Nurdan and Schneider, Kai Markus and Lurje, Georg and Raptis, Anastasia and Huang, Helen Ye Rim and Mueller, Sebastian and Reiberger, Thomas and Nahon, Pierre and Anstee, Quentin M. and Daly, Ann K. and Govaere, Olivier and Strnad, Pavel},
  title        = {Insulin-like Growth Factor-1 Reflects Liver Disease Stage and Improves Prediction of Liver-related Mortality},
  journaltitle = {Clinical gastroenterology and hepatology},
  year         = {2025},
  doi          = {10.1016/j.cgh.2025.02.030},
  keywords     = {,CRC1382-Project B09,CRC1382-Project A03,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A03},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {13},
  pages        = {2559--2569},
  publisher    = {Elsevier Science},
  reportid     = {RWTH-2025-05708},
  url          = {https://publications.rwth-aachen.de/record/1013796},
  volume       = {23},
}

@article{Schneider:1012647,
  author       = {Schneider, Kai Markus and Cao, Feng and Huang, Helen Ye Rim and Chen, Lanlan and Chen, Yazhou and Gong, Rongpeng and Raptis, Anastasia and Creasy, Kate Townsend and Clusmann, Jan Niklas and van Haag, Felix and Koop, Paul-Henry and Guillot, Adrien and Lüdde, Tom and Loomba, Rohit and Francque, Sven and Schneider, Carolin Victoria},
  title        = {The Lipidomic Profile Discriminates Between {MASLD} and Met{ALD}},
  journaltitle = {Alimentary pharmacology \& therapeutics},
  year         = {2025},
  doi          = {10.1111/apt.70012},
  keywords     = {,CRC1382-Project B09,CRC1382-Project B05,CRC1382-Project A01,CRC1382-Project A11,CRC1382-Project A11,CRC1382-Project A11},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {8},
  pages        = {1357--1371},
  publisher    = {Blackwell Science},
  reportid     = {RWTH-2025-05077},
  url          = {https://publications.rwth-aachen.de/record/1012647},
  volume       = {61},
}

@article{Schneich:1012467,
  author   = {Schöneich, Johannes and Dupont, Aline and Schlößer, Stefan and Schmitz, Matthias and Richter, Isabel and Gubbi, Narasimha Murthy Keshava Prasad and Cheng, Mingbo and Maié, Tiago and Jäverfelt, Sofia and Imdahl, Fabian and Toussaint, Christophe and Saliba, Antoine-Emmanuel and Kuppe, Christoph and Pelaseyed, Thaher and Costa, Ivan G. and Hornef, Mathias W.},
  title    = {Developmental factors drive the compartmentalised and discontinuous maturation of the small intestinal epithelium during the early postnatal period},
  year     = {2025},
  doi      = {10.1101/2025.05.15.654215},
  keywords = {,CRC1382-Project B01,CRC1382-Project Q03,CRC1382-Project B01},
  note     = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages    = {43 Seiten},
  reportid = {RWTH-2025-05009},
  url      = {https://publications.rwth-aachen.de/record/1012467},
}

@article{Simons:1022821,
  author       = {Simons, Britta and Nguyen, Hieu Trong and Panyot, Atscharah and Hager, Fabian Tobias and Kabbert, Johanna and Laouina, Asmae and Schreiber, Jonathan and Kopplin, Lydia and Rollenske, Tim and Clavel, Thomas and Pabst, Oliver},
  title        = {Clonal persistence dominates homeostatic intestinal IgA responses},
  journaltitle = {Immunity},
  year         = {2025},
  doi          = {10.1016/j.immuni.2025.11.005},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project B06,CRC1382-Project B06,CRC1382-Project Q04},
  location     = {[Cambridge, Mass.]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {3061--3074.e5},
  publisher    = {Cell Press},
  pubmed       = {pmid:41330367},
  reportid     = {RWTH-2025-10290},
  url          = {https://publications.rwth-aachen.de/record/1022821},
  volume       = {58},
}

@article{Spivak:1000158,
  author       = {Spivak, Igor and Guldiken, Nurdan and Usachov, Valentyn and Schaap, Frank G. and Olde Damink, Steven W. M. and Bouchecareilh, Marion and Lehmann, Alexandra and Fu, Lei and Mo, Fa-Rong and Kobazi Ensari, Gökce and Hufnagel, Franziska and Fromme, Malin and Preisinger, Christian and Strnad, Pavel},
  title        = {Alpha‐1 Antitrypsin Inclusions Sequester {GRP}78 in a Bile Acid–Inducible Manner},
  journaltitle = {Liver international},
  year         = {2025},
  doi          = {10.1111/liv.16207},
  keywords     = {,CRC1382-Project A03,CRC1382-Project A07,CRC1382-Project A07,CRC1382-Project A03},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {e16207},
  publisher    = {Wiley-Blackwell},
  pubmed       = {pmid:39665869},
  reportid     = {RWTH-2025-00202},
  url          = {https://publications.rwth-aachen.de/record/1000158},
  volume       = {45},
}

@article{Tulessin:1030355,
  author       = {Tulessin, Margaret and Beer, Ludwig and Roessler, Stephanie and Beckers, Anika and Castven, Darko and Calvisi, Diego Francesco and Chen, Xin and Lange, Sebastian and Pfarr, Nicole and Marquardt, Jens and Wirtz, Theresa and Berres, Marie-Luise and Steiger, Katja and Groll, Tanja and Mogler, Carolin},
  title        = {Detailed Characterization and Comparison of Mouse Models for Cholangiocarcinoma},
  journaltitle = {Laboratory investigation},
  year         = {2025},
  doi          = {10.1016/j.labinv.2025.104242},
  keywords     = {,CRC1382-Project B04,CRC1382-Project B04},
  location     = {London and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {12},
  pages        = {104242},
  publisher    = {Nature Publ. Group},
  reportid     = {RWTH-2026-02953},
  url          = {https://publications.rwth-aachen.de/record/1030355},
  volume       = {105},
}

@article{Xiong:1010310,
  author       = {Xiong, Ling and Beyer, Dustin and Liu, Na and Lehmann, Tina and Neugebauer, Sophie and Schaeuble, Sascha and Sommerfeld, Oliver and Ernst, Philipp and Svensson, Carl-Magnus and Nietzsche, Sandor and Scholl, Sebastian and Bruns, Tony and Gaßler, Nikolaus and Gräler, Markus H. and Figge, Marc Thilo and Panagiotou, Gianni and Bauer, Michael and Press, Adrian T.},
  title        = {Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models},
  journaltitle = {Pharmacological research},
  year         = {2025},
  doi          = {10.1016/j.phrs.2025.107581},
  keywords     = {,CRC1382-Project B07},
  location     = {[Amsterdam]},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {107581},
  publisher    = {Elsevier},
  pubmed       = {pmid:39761839},
  reportid     = {RWTH-2025-04006},
  url          = {https://publications.rwth-aachen.de/record/1010310},
  volume       = {212},
}

@inproceedings{Dukkart:1020040,
  author       = {Dukkart, Kseniia and Gonzalez, Catherine Esther and Parks, Nicole Andrea},
  title        = {Coscine and Data Stewardship},
  year         = {2025},
  doi          = {10.11588/heidok.00036358},
  location     = {Heidelberg},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  organization = {E-Science-Tage 2025, Heidelberg (Germany), 12 Mar 2025 - 14 Mar 2025},
  publisher    = {Heidelberg University Library},
  reportid     = {RWTH-2025-08741},
  url          = {https://publications.rwth-aachen.de/record/1020040},
}

@thesis{Ay:1008893,
  author      = {Ay, Ümran},
  title       = {Enterohepatic circulation of microbial bile salt conjugates and their interaction with human bile salt receptors},
  year        = {2025},
  abstract    = {Microbes in the gut communicate with the host through bile salts and host bile salt receptors like farnesoid X receptor (FXR) and Takeda G protein-coupled receptor 5 (TGR5). Recent research has uncovered thousands of microbial bile acid metabolites with potential to modulate these and other bile salt receptors. Structural variations in bile salts can influence their interaction with TGR5 and FXR, impacting their activation. While three microbially conjugated bile salts (MBSCs) were identified initially, over 100 different MBSCs have been reported since. The fate of these MBSCs in the host circulation and their effect on host signaling are only beginning to be explored. In this thesis, 6 different MBSCs were studied for their potential to activate FXR and TGR5 and act as substrates for intestinal and hepatic transporters taking up bile salt. The affinity of MBSCs for FXR and TGR5 was similar to, but not higher than, deconjugated bile salts and species conjugated in the liver. Only in the presence of a bile salt transporter (i.e. ASBT, OSTα/β or NTCP), MBSCs activated FXRα2 and FXRα4. To determine whether MBSCs can be absorbed and undergo enterohepatic circulation, mesenteric venous and portal blood collected during abdominal surgery was examined. In general, the studied MBSCs were below detection limits in these vessels but could be detected and quantified in bile of these patients. To test whether low levels of MBSCs in the circulation were due to luminal degradation by bacterial or host enzymes, an in vitro assay was performed. This test showed that L-amino acid containing MBSCs were readily cleaved by pancreatic carboxypeptidases and bacterial bile salt hydrolase. In contrast, the D-enantiomer of TyrC(DC)A was resistant to degradation by these enzymes. This suggests that enzymatic degradation in the intestinal lumen causes MBSCs to enter the host circulation in only minimal amounts that lie below analytical detection limits. This notion was supported by a pilot experiment in mice receiving D- or L-TyrCA by gavage, with a plasma response only observed after D-TyrCA administration. D-TyrCA was recovered in bile in notable amounts, implying that this MBSC undergoes efficient portal extraction and hepatobiliary secretion, and potentially recirculates like ‘regular’ bile salts. Other MBSCs, such as LeuCA and PheCA, were also detected, albeit at markedly lower levels, in bile of mice of either group. Although MBSCs are substrates for ASBT and OSTα/β, they do not seem to be absorbed in substantial amounts, with portal levels presumably in the subnanomolar range. It is unlikely that the tested MBSCs contribute to host bile salt signaling via TGR5 and FXR, as the affinity for these receptors is not higher than that of other, way more abundant bile salt species. Other bile salt receptors may be targeted more specifically by MBSCs. However, the current findings imply that the main role of the MBSCs may be restricted to an ecological function in the gut lumen rather. The initially discovered MBSCs are expected to behave as classical monovalent bile salt anions, but amidation with acidic or basic amino acids will lead to divalent or zwitterionic species with an influence on host signaling.In the second part of the thesis, the effect of other microbial modifications of bile salts, viz. oxidized (keto) bile salts and C3 (iso) and C5 (allo) epimers, on activation of TGR5 and FXR was investigated. TGR5 activation by lithocholic acid (LCA) was maintained after oxidation (3ketoLCA) or epimerization of C3 (isoLCA) but was abolished in case of the C5 epimers alloLCA and isoalloLCA. For deoxycholic acid (DCA), epimerization of C3 (isoDCA) and oxidation of C3 or C12 retained TGR5 activating properties. In contrast, epimerizing C3 in chenodeoxycholic acid (isoCDCA) abolished TGR5 agonism, whereas oxidation of C3 or C7 maintained agonistic activity. In general, trans-(allo) bile salts lost the ability to activate TGR5. The activation of FXR by DCA was independent of the presence of a bile salt transporter (ASBT or NTCP), while the oxidation of C3 (3ketoDCA) required an importer in order to activate FXR. For CDCA, FXR activation was abolished by oxidation of C7 (7ketoCDCA), whereas FXR agonism was not affected by modifications at C3. CDCA and its agonistic variants, activated FXR in a transporter-dependent manner. In summary, microbial modifications of bile salts on positions C3, C5, C7 and C12, can influence their capacity to activate TGR5 and FXR, with seemingly subtle modifications leading to loss of receptor agonism. Structural changes may also affect their cellular import via ASBT and NTCP, obscuring interpretation of loss of activation in case of FXR. In summary, MBSCs activated FXR and TGR5 and were substrates for the bile salt transporters ASBT, OSTα/β, and NTCP. However, the affinity of MBSCs for FXR and TGR5 was similar to, but not greater than, deconjugated bile salts and host-conjugated species. The studied MBSCs were quantified in the bile of patients with pancreatic head cancer, but MBSCs were not detected in the blood of systemic circulation of these patients. MBSCs did not enter the host circulation in an intact form, probably due to enzymatic degradation in the intestinal lumen. The pilot experiment in which mice received D- or L- TyrCA by gavage, shows that only MBSCs resistant to cleavage by host and bacterial enzymes (here D-TyrCA), potentially recirculate. Although MBSCs are substrates for bile acid transporters and agonists of TGR5 and FXR, their relative low levels in portal or systemic blood make a major contribution of MBSCs to signaling via these bile salt receptors unlikely. Whether MBSCs modulate the activity of other bile salt receptors remains to be tested. However, the current results suggest that the primary role of MBSC may not be to modulate host signaling and may be limited to an ecological function within the intestinal lumen. Future research should focus on characterizing the quantities of the MBSCs and the affinity of isolated MBSCs or mixtures for the diverse potential bile acid receptors. For the former, an improved analytical methodology is needed to determine subnanomolar amounts.},
  doi         = {10.18154/RWTH-2025-03224},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project A07,CRC1382-Project A06,CRC1382-Project B01,CRC1382-Project Q03},
  location    = {Aachen},
  namea       = {Blank, Lars Mathias and Hornef, Mathias W.},
  nameatype   = {supervisor},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-03224},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1008893},
}

@thesis{Beckers:1019294,
  author      = {Beckers, Anika},
  title       = {Dendritic cells as cellular targets of gut-liver communication in chronic liver disease and hepatocellular carcinogenesis},
  year        = {2025},
  abstract    = {The liver is continuously exposed to gut derived factors via the portal vein which shapes a highly specialized immune-tolerant environment. Dendritic cells (DCs) play a crucial role in maintaining immune balance by preventing excessive activation while preserving immune surveillance. However, this delicate balance can be disrupted in chronic liver disease (CLD). In this condition, the gut-liver axis, driven by portal hypertension and increased intestinal permeability, facilitates microbial translocation and inflammatory signaling from the gut to the liver, potentially impairing the DCs to function and to contribute to immune dysregulation and hepatocellular carcinoma (HCC) progression. This thesis analyses how the gut-liver axis modulates conventional DCs subsets in CLD and HCC in an etiology-dependent manner. Our findings show that gut permeability and microbial translocation differentially shape intrahepatic DC subsets phenotype and function based on disease context. We demonstrate that cDC1s are associated with improved overall survival, while cDC2 expansion correlates with disease progression in an etiology-dependent manner. By analyzing experimental mouse models of toxic liver injury and HCC alongside human liver tissue samples from nonalcoholic steatohepatitis (NASH) and NASH-associated HCC patients, we observed a consistent shift from cDC1 to cDC2 dominance, independent of CLD etiology. Across all conditions, cDC1s exhibited reduced activation and increased programmed cell death ligand 1 (PD-L1) expression, suggesting an impaired immune responsiveness. Although cDC2s showed reduced activation, its PD-L1 expression varied by etiology, indicating the existence of distinct immunosuppressive mechanisms.Using the Dendra2 photoconvertible mouse model, we tracked gut derived DCs and confirmed their contribution to the intrahepatic immune landscape. This reinforces the gut-liver axis as a key determinant of hepatic immune regulation. Further analysis in the chronic gut-leakage JAM-A mouse model showed that CLD-associated gut permeability differentially affects the intrahepatic cDC functioning. In our toxin-induced CLD model, cDC activation was suppressed, while in the metabolic liver injury model, cDCs appeared to adopt a more immunogenic yet tolerogenic phenotype. Additionally, analysis of circulating cDC from the portal, hepatic, and peripheral veins in CLD patients revealed distinct subset distributions, highlighting their differential contributions to hepatic immunity. Cellular indexing of transcriptomes and epitopes by sequencing identified distinct cDC1, cDC2, and DC3 subsets, showing that these cells undergo pre-hepatic activation and acquire a mature DC phenotype enriched with immunoregulatory molecules (mregDC) in the intestinal microvasculature before reaching the liver. Notably, mregDC1s exhibited a highly activated inflammatory profile alongside elevated PD-L1 expression. These findings suggest that mregDC1 levels may serve as a predictive marker for immune checkpoint therapy response, potentially explaining their association with improved overall survival. This underscores the role of gut-liver immune interactions in preconditioning DC function and shaping intrahepatic immunity. In conclusion, this study highlights the gut-liver axis as a critical regulator of intrahepatic DC function, linking gut-derived immune modulation to CLD progression and HCC development. These insights indicate cDC subsets as potential prognostic markers and therapeutic targets, offering new opportunities for immune-based interventions in CLD and HCC.},
  doi         = {10.18154/RWTH-2025-08313},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project B04,CRC1382-Project B04},
  location    = {Aachen},
  namea       = {Panstruga, Ralph and Berres, Marie-Luise},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-08313},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1019294},
}

@thesis{Bharadwaj:1020150,
  author      = {Bharadwaj, Sraddha S},
  title       = {Early intestinal neoplasia induces a local immunosuppressive environment through macrophage-regulatory T cell interactions},
  year        = {2025},
  abstract    = {Colorectal cancer (CRC) develops through a stepwise process beginning with early epithelial transformation and immune reprogramming. However, the immunological events that define this initial phase remain poorly understood. Using a genetically engineered mouse model in which continuous Wnt signaling drives early intestinalneoplasia, we investigated how localized tumoral changes reshape immune cell populations within the intestine and the liver. Particularly, we wanted to focus on how tumor regulatory T cells (Tregs) modulate CD8+ T cells and which immune cells control tumor Tregs in the intestine. We also investigated alterations in the immune cellpopulation in the liver upon intestinal neoplasia. We observed that tumor Tregs control the accumulation of activated CD8+ T cells, since we observed increased frequencies of activated CD8+ T cells when tumor Tregs did not accumulate in a model of MC38 tumor cell transplantation. Additionally, single-cell RNA sequencing showed that macrophages and dendritic cells (DCs) strongly respond to neoplasia, while flow cytometry demonstrated a parallel accumulation of these cells in the intestine. Multiplex immunofluorescence images suggested that macrophages and tumor Tregs interact with each other, and bone marrow chimeras revealed a role for antigen presentation by macrophages in promoting tumor Treg accumulation. On the other hand, tumor Treg frequencies were also increased in the mesenteric lymph node, however, the contribution of DCs in tumor Treg accumulation appeared to be minimal. Re-analysis of the transcriptomic data from macrophages and DCs revealed that upon neoplasia, both cell types express higher levels of Plet1, which has been previously linked to tissue repair. Anearly immune response was also observed in the liver since we observed infiltration of hepatic monocytes upon intestinal neoplasia. Our results suggest that tumor Treg-myeloid cell interaction controls inflammatory responses during intestinal neoplasia. This was also accompanied by changes in the liver, which indicate potential priming forfuture tumor cell seeding. Collectively, these findings shed light on the immune changes that occur in the earliest stages of colorectal cancer and may be useful in the development of therapeutic strategies aimed at intercepting tumor progression along the gut-liver axis even before it is fully established.},
  doi         = {10.18154/RWTH-2025-08803},
  institution = {RWTH Aachen University},
  location    = {Aachen},
  namea       = {Pabst, Oliver and Zenke, Martin},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-08803},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1020150},
}

@thesis{Haque:1022918,
  author      = {Haque, Madhuri},
  title       = {{PNPLA}3I148M-associated {MASLD} susceptibility},
  year        = {2025},
  abstract    = {Rationale: The PNPLA3I148M variant is a major genetic risk factor for MASLD, yet its variable penetrance suggests additional environmental triggers. Gut microbial dysbiosis is implicated in MASLD pathogenesis, yet its interaction with PNPLA3I148M remains uncertain. This study explores how dysbiosis synergizes with PNPLA3I148M to drive metabolic dysfunction and MASLD progression. Methods: Gut microbiota profiles from 146 MASLD patients were analyzed. To mechanistically model the gene-diet-microbiome interaction, a murine “dual-hit” model combining Pnpla3I148M and Nlrp6 deficiency was developed. Mice were fed a CHOW or HFD, and subsequently subjected to metabolic, lipidomic, and microbial profiling. Interventions included antibiotic treatment, fecal microbiota transplantation, and Akkermansia muciniphila supplementation. Results: In MASLD patients, gut dysbiosis significantly correlated with metabolic variance in PNPLA3I148M-carriers, manifesting as an adiposity-dependent rise in serum triglycerides. In mice, Pnpla3I148M alone caused mild steatosis under obesogenic conditions, whereas combined with Nlrp6 deficiency it induced spontaneous MASLD even on CHOW diet, worsened by HFD. This phenotype featured gut barrier dysfunction, dysbiosis, hepatic lipid remodeling, and mitochondrial impairment. Mechanistically, dysbiosis enriched bile acid-transforming and ceramide-producing bacteria signature (e.g., Clostridium scindens, Alistipes finegoldii, Oscillibacter), elevating hydrophobic secondary bile acids and ceramides in portal circulation. These metabolites impaired hepatic mitochondrial oxidative phosphorylation, increased ROS, suppressed bile acid synthesis (Cyp7a1, Cyp27a1), and activated lipid uptake pathways (Srebf2/Ldlr, Cd36). Upregulation of ceramide synthase 6 (CerS6) and lipid droplet stabilizers (Plin2, Lipa) promoted intracellular lipid retention, establishing a self-amplifying gut–liver metabolic loop. Antibiotic depletion disrupted this axis, reversing metabolic dysfunction. Dysbiotic FMT transferred pathology to healthy mice, while complete microbiome restoration robustly improved metabolic health; single-strain Akkermansia treatment was partially effective. Conclusion: My findings establish PNPLA3I148M and dysbiosis as synergistic drivers of MASLD, with microbial dysregulation exacerbating genetic susceptibility through gut-liver axis disruption. Therapeutic modulation of the microbiome may offer a targeted strategy for high-risk PNPLA3I148M-carriers.},
  doi         = {10.18154/RWTH-2025-10356},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project A06,CRC1382-Project B09,CRC1382-Project A08},
  location    = {Aachen},
  namea       = {Blank, Lars Mathias and Schneider, Kai Markus},
  nameatype   = {supervisor},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-10356},
  subtitle    = {The pivotal role of microbiota-driven metabolic dysregulation},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1022918},
}

@thesis{Schraven:1002480,
  author      = {Schraven, Sarah},
  title       = {Characterization of the gut-liver axis using fluorescence-based hybrid imaging techniques},
  year        = {2025},
  abstract    = {Fluorescence imaging can longitudinally monitor the biodistribution of fluorophore-labeled drugs, nanoparticles, and antibodies. In this context, fluorescent dyes in biomedical imaging and the accuracy of tracking and characterizing biological processes in the body were investigated. While the interaction of dye labels with transporters is known, its impact on biodistribution was hardly studied. This study compared tumor cell uptake and biodistribution of four near-infrared fluorescent dyes and dye-labeled nanocarriers in A431 tumor-bearing mice. Hydrophobicity of the dyes influenced tumor cell uptake and elimination of free dyes, while dye labeling significantly influenced tumor accumulation and biodistribution of nanocarriers. This study highlights the need for low-interference dyes and further investigation of dye labels to achieve the most unbiased results possible. In our evaluation, AF750 and IRDye750 best qualified for labeling hydrophilic nanocarriers. Therefore, in the following study immunoglobulins were labeled with AF750, which aimed at improving technically the accuracy of optical imaging. CT in fluorescence imaging provides anatomical information for generating scattering and absorption maps aiding fluorescence tomography (FLT) reconstruction. However, its limited soft tissue contrast could lead to inaccurate FLT reconstruction and quantification. Therefore, a hybrid imaging approach using MRI was established and compared to the state-of-the-art (CT-FLT). The study found comparable dye quantification for Cy7 inserts and organs containing fluorescent immunoglobulins for FLT reconstructions aided by CT, MRI or CT-MRI, with or without extending scattering maps. MRI enabled the visualization of specific organs and improved segmentation, allowing more accurate fluorescence signal assignments. The novel trimodal CT-MRI-FLT whole-body imaging approach facilitated more nuanced pharmacokinetic analyses with the option for tissue characterization. In conclusion, this research investigated and optimized both the selection of dyes for biodistribution analyses and the anatomical modality for whole-body FLT in a preclinical setting.},
  doi         = {10.18154/RWTH-2025-00559},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project Q01},
  location    = {Aachen},
  namea       = {Kießling, Fabian and Pabst, Oliver},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-00559},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1002480},
}

@thesis{Schtz:1023245,
  author      = {Schütz, Monika},
  title       = {B-cell phenotypes and {BCR} clonality in the human gut-liver axis},
  year        = {2025},
  abstract    = {The gastrointestinal tract is constantly exposed to enormous amounts of potentially harmful antigens through dietary intake and the microbiota. Therefore the immune response of the gut in precise coordination with the liver is critical to prevent pathogens from entering the systemic circulation. B-cells play an important role in this defense, and although the intestinal B-cell properties has been studied to some extent, only limited information is available on the human hepatic B-cell compartment. To obtain a complete picture, we performed an in-depth phenotypic and repertoire analysis of B-cells in the human gut-liver axis, both under normal conditions and in diseases known to involve interactions between these two organs. Our analysis revealed that the distribution of B-cell subsets and the expression of markers associated with cell migration, particularly CCR9 and integrin beta 1, differed in hepatic B-cells from their intestinal and blood counterparts. In addition, we found that plasma cells of the liver and intestine did not exhibit clonal sharing. By extending the analysis to non-alcoholic fatty liver disease (NAFLD), we observed no major differences in both the phenotype and repertoire of intestinal B-cells at different disease stages. Finally, we confirmed the impairment of the B-cell compartment with a reduction of memory B-cells in patients with liver cirrhosis. We extended these observations to the B-cells of the peritoneal cavity and demonstrated that these alterations were more pronounced in patients with poor clinical outcome. In addition, we found a decreased expression of the B-cell-activating factor receptor (BAFFR) in diseased patients. Our results thus provide new insights into B-cells in the human gut and liver. We suggest that hepatic plasma cells represent a small but tissue-specific population that potentially performs specific functions in the gut-liver axis. Although we showed that there is no significant phenotypic or repertoire difference in the different stages of NAFLD, our analysis cannot exclude the role of intestinal B-cells in the development and progression. Finally, we were able to confirm the alterations in the B-cell subsets in cirrhotic patients. Our observation of decreased expression of BAFFR could also help to determine the reason for the decreased memory B-cell population. In conclusion, our detailed characterization of B-cells in the human gut-liver axis contributes to a deeper understanding of the interaction of these two organs, both in a healthy immune response and under dysregulated conditions associated with chronic liver disease, and thus provides new approaches for further studies.},
  doi         = {10.18154/RWTH-2025-10597},
  institution = {RWTH Aachen University},
  keywords    = {,CRC1382-Project B07},
  location    = {Aachen},
  namea       = {Pabst, Oliver and Bruns, Tony},
  nameatype   = {supervisor},
  note        = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages       = {1 Online--Ressource : Illustrationen},
  publisher   = {RWTH Aachen University},
  reportid    = {RWTH-2025-10597},
  subtitle    = {A tissue-specific analysis},
  type        = {phdthesis},
  url         = {https://publications.rwth-aachen.de/record/1023245},
}

@article{BenedUbieto:1030183,
  author       = {Benedé-Ubieto, Raquel and Estévez-Vázquez, Olga and Acar, Rana and Leal-Lassalle, Hector and Gutierrez, Alejandro H. and Redondo-Urzainqui, Ana and Iborra, Salvador and Odintsova, Vera E. and Tyakht, Alexander and Herranz, José María and Firat, Zehra and Basol, Merve and Korkmaz, Busra and Sanz-García, Carlos and Juanola, Oriol and Caparrós, Esther and Francés, Rubén and Ciudin, Andreea and Pericàs, Juan M. and Gómez-Santos, Beatriz and Aspichueta, Patricia and Treichel, Nicole and Clavel, Thomas and Reißing, Johanna and Bruns, Tony and Bartneck, Matthias and Mazariegos, Marina S. and Wolters, Justina Clarinda and Jorquera, Gonzalo and Liedtke, Christian and Vaquero, Javier and Bañares, Rafael and Cakan-Akdogan, Gulcin and Ávila, Matías A. and Konu, Ozlen and Cubero, Francisco Javier and Nevzorova, Yulia A.},
  title        = {Alcohol consumption in metabolic dysfunction-associated steatotic liver disease ({MASLD}): understanding the gut–liver crosstalk for clinical translation},
  journaltitle = {Gut microbes},
  year         = {2026},
  doi          = {10.1080/19490976.2026.2631834},
  keywords     = {,CRC1382-Project B07,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project A02,CRC1382-Project Q02},
  location     = {Austin, Tex.},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {2631834},
  publisher    = {Landes Bioscience},
  reportid     = {RWTH-2026-02823},
  url          = {https://publications.rwth-aachen.de/record/1030183},
  volume       = {18},
}

@article{Bhargava:1022941,
  author       = {Bhargava, Shruti and Rao, Zhuangting and Vanholder, Raymond and Tacke, Frank and Noels, Heidi and Jankowski, Vera and Hermann, Juliane and Jankowski, Joachim},
  title        = {The impact of gut-liver-derived mediators on the organ crosstalk with brain, heart, and kidney: A systematic review},
  journaltitle = {Molecular metabolism},
  year         = {2026},
  doi          = {10.1016/j.molmet.2025.102295},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04,CRC1382-Project B05},
  location     = {Oxford and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages        = {102295},
  publisher    = {Elsevier},
  pubmed       = {pmid:41325840},
  reportid     = {RWTH-2025-10376},
  url          = {https://publications.rwth-aachen.de/record/1022941},
  volume       = {103},
}

@article{Erdem:1030180,
  author    = {Erdem, Merve and Roth, Johanna and Knobloch, Jana and Nolting, Jochen and Hatten, Hannes and Sahin, Eray and Schön, Felix and Halbfeld, Sandra and Treichel, Nicole and Clavel, Thomas and Bülow, Roman David and Liedtke, Christian and Cramer, Thorsten},
  title     = {A mixture of plant polyphenols unexpectedly aggravates liver metastasis of colorectal cancer in mice},
  year      = {2026},
  doi       = {10.64898/2026.02.15.703962},
  keywords  = {,CRC1382-Project A05,CRC1382-Project Q02,CRC1382-Project A02,CRC1382-Project Q03,CRC1382-Project Q02},
  location  = {Cold Spring Harbor},
  note      = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  pages     = {41 Seiten},
  publisher = {Cold Spring Harbor Laboratory, NY},
  reportid  = {RWTH-2026-02820},
  url       = {https://publications.rwth-aachen.de/record/1030180},
}

@article{Lee:1028390,
  author       = {Lee, Chi-Hsien and Bui, Thi Phuong Nam and Petitfils, Camille and Jian, Ching and Wong, Giselle C. and Puel, Anthony and Le Roy, Tiphaine and Bellais, Samuel and Ben Abdallah, Bouthaina and Nehlich, Mélanie and Leicht, Thomas and Jia, Manyi and Hoyles, Lesley and Federici, Massimo and Fernández-Real, Jose Manuel and Burcelin, Remy and Dumas, Marc-Emmanuel and Delzenne, Nathalie M. and Clavel, Thomas and Boeren, Sjef and Troise, Antonio Dario and Scaloni, Andrea and Muccioli, Giulio G. and De Vos, Willem M. and Van Hul, Matthias and Cani, Patrice D.},
  title        = {Novel myo -inositol to butyrate fermentation pathway in the prevalent human gut species Dysosmobacter welbionis, a bacterium associated with improved metabolic and liver health},
  journaltitle = {Gut},
  year         = {2026},
  doi          = {10.1136/gutjnl-2025-336617},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  publisher    = {BMJ Publishing Group},
  reportid     = {RWTH-2026-01604},
  url          = {https://publications.rwth-aachen.de/record/1028390},
}

@article{Mikolajetz:1032436,
  author       = {Mikolajetz, Dustin and Kalim, Sahir and Noels, Heidi and Wu, Zhuojun and Jankowski, Vera and Jankowski, Joachim and de la Puente-Secades, Sofía},
  title        = {Impact of amino acid supplementation on cardiovascular and chronic kidney diseases: a systematic review},
  journaltitle = {Cardiovascular research},
  year         = {2026},
  doi          = {10.1093/cvr/cvag007},
  keywords     = {,CRC1382-Project A04,CRC1382-Project A04},
  location     = {Oxford},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {178--194},
  publisher    = {Oxford University Press},
  reportid     = {RWTH-2026-03524},
  url          = {https://publications.rwth-aachen.de/record/1032436},
  volume       = {122},
}

@article{Muschaweck:1029383,
  author       = {Muschaweck, Moritz and Gutbier, Christian and Sellge, Gernot and Pappa, Angeliki and Wenzl, Tobias Gregor and Hamesch, Karim and Wagner, Norbert and Schippers, Angela},
  title        = {Soluble mucosal addressin cell adhesion molecule 1 is a biomarker for pediatric ulcerative colitis},
  journaltitle = {Molecular and Cellular Pediatrics},
  year         = {2026},
  doi          = {10.1186/s40348-026-00221-8},
  keywords     = {,CRC1382-Project B02,CRC1382-Project B02},
  location     = {Berlin and Heidelberg and others},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {1},
  pages        = {8},
  publisher    = {SpringerOpen},
  reportid     = {RWTH-2026-02276},
  url          = {https://publications.rwth-aachen.de/record/1029383},
  volume       = {13},
}

@article{Thelen:1020793,
  author       = {Thelen, Anne Carina and Andreani, N. and Korten, Nele and Neumann, M. and Verspohl, Valerie and van Egmond, M. and Kneisel, Lilly and Voelz, Clara and Blischke, Larissa and Baines, J. F. and Baier, Jasmin and Schumacher, Jan and Kießling, Fabian and Herpertz-Dahlmann, Beate and Beyer, Cordian and Keller, L. and Seitz, J. and Trinh, Stefanie Nhu-Binh},
  title        = {The Influence of Omega‐3 Fatty Acids and Probiotics on Hippocampal Inflammation and Glial Cells in a Chronic Anorexia Nervosa Rat Model},
  journaltitle = {The international journal of eating disorders},
  year         = {2026},
  doi          = {10.1002/eat.24574},
  keywords     = {,CRC1382-Project Q01},
  location     = {New York, NY},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {260--275},
  publisher    = {Wiley},
  reportid     = {RWTH-2025-09242},
  url          = {https://publications.rwth-aachen.de/record/1020793},
  volume       = {59},
}

@article{Young:1028389,
  author       = {Young, Veronika and Dohai, Bushra and Halder, Hridi and Fernandez-Macgregor, Jaime and van Heusden, Niels S. and Hitch, Thomas C. A. and Weller, Benjamin and Hyden, Patrick and Saha, Deeya and Pieren, Daan K. J. and Rittchen, Sonja and Lambourne, Luke and Maseko, Sibusiso B. and Lin, Chung-Wen and Tun, Ye Min and Bibus, Jonas and Pletschacher, Luisa and Boujeant, Mégane and Choteau, Sébastien A. and Bergogne, Lou and Perrin, Jérémie and Ober, Franziska and Schwehn, Patrick and Rothballer, Simin T. and Altmann, Melina and Altmann, Stefan and Strobel, Alexandra and Rothballer, Michael and Tofaute, Marie and Kotlarz, Daniel and Heinig, Matthias and Clavel, Thomas and Calderwood, Michael A. and Vidal, Marc and Twizere, Jean-Claude and Vincentelli, Renaud and Krappmann, Daniel and Boes, Marianne and Falter, Claudia and Rattei, Thomas and Brun, Christine and Zanzoni, Andreas and Falter-Braun, Pascal},
  title        = {Effector–host interactome map links type {III} secretion systems in healthy gut microbiomes to immune modulation},
  journaltitle = {Nature microbiology},
  year         = {2026},
  doi          = {10.1038/s41564-025-02241-y},
  keywords     = {,CRC1382-Project A05,CRC1382-Project Q02},
  location     = {London},
  note         = {SFB 1382: Die Darm-Leber-Achse -- Funktionelle Zusammenhänge und therapeutische Strategien (403224013)},
  number       = {2},
  pages        = {442--460},
  publisher    = {Nature Publishing Group},
  reportid     = {RWTH-2026-01603},
  url          = {https://publications.rwth-aachen.de/record/1028389},
  volume       = {11},
}